CAS 98769-84-7; Reboxetine mesylate hydrate

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CAS:

98769-84-7

分子式:

C₁₉H₂₃NO₃ · CH₃SO₃H · xH₂O

分子量:

409.50 (anhydrous basis)

英文名称:

Reboxetine mesylate hydrate

(2R)-rel-2-[(R)-(2-Ethoxyphenoxy)phenylmethyl]morpholine

用途:

Reboxetine mesylate是一种降低肾上腺素重新吸收的抑制剂，抑制[3H]小鼠下丘脑突触体对碘化钾的吸收量和[3H]5-HT小鼠纹状体突触对碘化钾吸收的Ki值分别为8.2nM和1070nM。

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

详情

R863997

MACKLIN

Reboxetine mesylate

≥99%

551元/10mg;

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储存：2-8°C
状态：白色-棕褐色固体

R794851

MACKLIN

Reboxetine mesylate

10mM in DMSO

367元/1ml;

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储存：-20°C

R6527

Sigma-Aldrich

Reboxetine mesylate hydrate

>96% (HPLC), solid

3446.51元/5 MG; 14795.2元/25 MG;

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产品说明

应用

Reboxetine mesylate hydrate has been used as a selective norepinephrine transport blocker:

to study its effects on the surge of dopamine in the cortex of mice brain
to study its anti-immobility effects on the behavior of mice
to analyze its effects on the probabilistic reversal learning task in rodents

包装

5, 25 mg in glass bottle

生化/生理作用

Reboxetine exhibits anti-depressant activity.
Reboxetine mesylate hydrate is a selective noradrenaline uptake inhibitor.

特点和优势

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式	C₁₉H₂₃NO₃ · CH₃SO₃H · xH₂O
分子量	409.50 (anhydrous basis)
MDL编号	MFCD11046031
PubChem化学物质编号	24724592
NACRES	NA.77

产品性质

质量水平	100
测定	>96% (HPLC)
形式	solid
储存条件	desiccated
颜色	white to tan
溶解性	H₂O: >5 mg/mL at ≤60 ℃
运输	wet ice
储存温度	2-8℃
SMILES string	O.CS(O)(=O)=O.CCOc1ccccc1O[C@@H]([C@H]2CNCCO2)c3ccccc3
InChI	1S/C19H23NO3.CH4O3S.H2O/c1-2-21-16-10-6-7-11-17(16)23-19(15-8-4-3-5-9-15)18-14-20-12-13-22-18;1-5(2,3)4;/h3-11,18-20H,2,12-14H2,1H3;1H3,(H,2,3,4);1H2/t18-,19-;;/m1../s1
InChI key	SZPHEVAYLIVGRC-BAMQSBMESA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)

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