CAS 98625-26-4; s (-)-bay k 8644

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CAS:

98625-26-4

分子式:

C16H15F3N2O4

分子量:

356.30

沸点:

429.2°C at 760 mmHg

英文名称:

s (-)-bay k 8644

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

B891481

MACKLIN

(S)-2,6-二甲基-5-硝基-4-(2-三氟甲基)苯基)-1,4-二氢吡啶-3-甲酸甲酯

98%

328元/5mg; 386元/10mg; 661元/25mg;

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储存：2-8°C，干燥密封
状态：黄色固体

B133

Sigma-Aldrich

(S)-(-)-Bay K8644

≥98% (HPLC), solid

2684.1元/1 MG; 10721.3元/5 MG;

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产品说明

一般描述

(S)-(-)-Bay K8644, a dihydropyridine compound is a Ca²⁺ channel activator. It is an enantiomer of Bay K 8644.

应用

(S)-(-)-Bay K8644 has been used as a L-type calcium channel (LTCC) agonist in the suprachiasmatic nucleus (SCN) slices. It has also been used as a LTCC agonist to induce arrhythmia in rats.

包装

1, 5 mg in glass bottle

生化/生理作用

(S)-(-)-Bay K8644 enhances Ca²⁺ current, whereas the (+)-Bay K 8644 is a weak Ca²⁺ channel antagonist. Bay K 8644 is lipophilic and it effectively scavenges superoxide anions.

特点和优势

This compound is featured on the Calcium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

法律信息

Manufactured and sold with the permission of Bayer AG.

基本信息

经验(实验)分子式	C₁₆H₁₅F₃N₂O₄
分子量	356.30
MDL编号	MFCD00153769
PubChem化学物质编号	24891582
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	solid
颜色	yellow
溶解性	H₂O: slightly soluble ethanol: soluble (Organic solutions are stable for at least 20 days at RT.)
储存温度	2-8℃
SMILES string	COC(=O)C1=C(C)NC(C)=C([C@H]1c2ccccc2C(F)(F)F)[N+]([O-])=O
InChI	1S/C16H15F3N2O4/c1-8-12(15(22)25-3)13(14(21(23)24)9(2)20-8)10-6-4-5-7-11(10)16(17,18)19/h4-7,13,20H,1-3H3/t13-/m0/s1
InChI key	ZFLWDHHVRRZMEI-ZDUSSCGKSA-N
Gene Information	human ... ADORA3(140) rat ... Adora1(29290), Adora2a(25369)

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319
预防措施声明	P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
危险分类	Eye Irrit. 2 - Skin Irrit. 2
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves

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