CAS 985-12-6; isoquinoline, 1,2,3,4-tetrahydro-6,7-diethoxy-1-((3,4-diethoxyphenyl)methylene)

CAS:

985-12-6

分子式:

C₂₄H₃₁NO₄ • HCl

分子量:

434

英文名称:

isoquinoline, 1,2,3,4-tetrahydro-6,7-diethoxy-1-((3,4-diethoxyphenyl)methylene)

6,7,3',4'-tetraethoxy-1-benzal-1,2,3,4-tetrahydroisoquinoline hydrochloride

drotaverin hydrochloride

drotaverine hydrochloride

drotaverinium chloride

isodihydroperparine hydrochloride

1-(3,4-diethoxybenzylidene)-6,7-diethoxy-1,2,3,4-tetrahydro-isoquinolin

no-spa

no-spa hydrochloride

tetraspasmin-lefa

1,2,3,4-tetrahydro-6,7-diethoxy-1-((3,4-diethoxyphenyl)methylene)-isoquinolinhydrochloride

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用途:

Drotaverine hydrochloride is an alkaloid that has been described as an inhibitor of phosphodiesterase 4 and negative allosteric modulator of L-type Ca2+ channels.

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

详情

D913244

MACKLIN

盐酸屈他维林

98%

3520元/50mg;

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储存：-20°C，密闭，干燥

SML1942

Sigma-Aldrich

Drotaverine hydrochloride

≥95% (HPLC)

973.81元/10 MG; 3943.82元/50 MG;

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产品说明

生化/生理作用

Drotaverine (Drotaverin) is an isoquinoline-based PDE4-selective phosphodiesterase (PDE) inhibitor and an L-type voltage-dependent (voltage-operated) calcium channel (L-VDCC or L-VOCC) blocker that exhibits in vivo antispasmodic efficacy without anticholinergic effects.
It is a benzylisoquinoline derivative. Drotaverine acts as a smooth muscle relaxant.

基本信息

经验(实验)分子式	C₂₄H₃₁NO₄ · HCl
分子量	433.97
MDL编号	MFCD00347721
NACRES	NA.77

产品性质

质量水平	100
测定	≥95% (HPLC)
形式	powder
储存条件	desiccated
颜色	white to beige
溶解性	DMSO: 2 mg/mL, clear (warmed)
储存温度	2-8℃
SMILES string	CCOC1=CC=C(/C=C2C3=C(CCN/2)C=C(OCC)C(OCC)=C3)C=C1OCC.[H]Cl
InChI	1S/C24H31NO4.ClH/c1-5-26-21-10-9-17(14-22(21)27-6-2)13-20-19-16-24(29-8-4)23(28-7-3)15-18(19)11-12-25-20;/h9-10,13-16,25H,5-8,11-12H2,1-4H3;1H/b20-13-;
InChI key	JBFLYOLJRKJYNV-MASIZSFYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302
预防措施声明	P301 + P312 + P330
危险分类	Acute Tox. 4 Oral
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable