CAS 98079-52-8; 盐酸洛美沙星; Lomefloxacin HCl

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货号

品牌

产品名称

规格

包装、参考价格

L797790

MACKLIN

盐酸洛美沙星

10mM in H2O

185元/1ml;

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储存：-20°C

L812311

MACKLIN

盐酸洛美沙星

98%

32元/1g; 105元/5g; 241元/25g; 873元/100g;

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储存：-20°C
状态：白色到浅黄色粉末

L0216

TCI

Lomefloxacin Hydrochloride

>98.0%(T)(HPLC)

350元/5G; 1650元/25G;

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基本信息

纯度/分析方法	>98.0%(T)(HPLC)
分子式/分子量	C₁₇H₁₉F₂N₃O₃・HCl = 387.81
外观与形状(20℃)	固体
Reaxys-RN	7506829
PubChem物质ID	87560160
Merck Index (14)	5562
MDL编号	MFCD00214312

技术规格

Appearance	White to Orange to Green powder to crystal
Purity(HPLC)	min. 98.0 area%
Purity(Nonaqueous Titration)	min. 98.0 %

安全信息

图形或危害标志
信号词	警告
危险性说明	H302 : 吞咽有害。 H317 : 可能造成皮肤过敏反应。
防范说明	P501 : 将内装物/容器送到批准的废物处理厂处理。 P261 : 避免吸入粉尘/烟/气体/烟雾/蒸气/喷雾。 P272 : 受沾染的工作服不得带出工作场地。 P270 : 使用本产品时不要进食、饮水或吸烟。 P264 : 作业后彻底清洗皮肤。 P280 : 戴防护手套。 P302 + P352 : 如皮肤沾染：用水充分清洗。 P362+P364 : 脱掉沾污的衣服，清洗后方可重新使用。 P333 + P313 : 如发生皮肤刺激或皮疹：求医/就诊。 P301 + P312 + P330 : 如误吞咽：如感觉不适，呼叫急救中心/医生。漱口。

相关法规

RTECS#

VB1997500

363260

J&K

Lomefloxacin Hydrochloride

98%

656元/5G;

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基本信息

分子式	C₁₇H₁₉F₂N₃O₃·HCl
分子量	387.81
熔点	290-300
MDL编码	MFCD00214312
Beilstein	7506829
存储条件	Freezer -20℃

安全信息

图形或危害标志
提示语	Warning
危险说明	H302 H317
防范说明	P261 P264 P270 P272 P280 P301+P312+P330
WGK	3
RTECS	VB1997500

L2906

Sigma-Aldrich

Lomefloxacin Hydrochloride

436.63元/1 G; 2619.62元/10 G;

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产品说明

一般描述

Chemical structure: fluoroquinolone

应用

Lomefloxacin is a fluoroquinolone antibiotic that is commonly used to treat bacterial infections, including bronchitis and urinary tract infections. It is used as a pre-operative prophylactic to prevent urinary tract infection caused by S. pneumoniae, H. influenzae, S. aureus, P. aeruginosa, E. cloacae, P. mirabilis, C. civersus, S. asprphyticus, E. coli, and K. pneumoniae. It is used to induce genomic instability in mice and modification of the kinetics of growth of Gram-negative bacteria.

包装

1, 10 g in poly bottle

生化/生理作用

Lomefloxacin is a bactericidal fluoroquinolone agent that is active against gram-negative and gram-positive organisms. Lomefloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, which are needed for the transcription and replication of bacterial DNA. DNA gyrase is thought to be the primary quinolone target for gram-negative bacteria. Topoisomerase IV is thought to be the primary target in gram-positive organisms. The inhibition of the topoisomerases results in strand breakage of the bacterial chromosome, supercoiling, and resealing. Therefore, DNA replication and transcription is inhibited.

基本信息

经验(实验)分子式	C₁₇H₁₉F₂N₃O₃ · HCl
分子量	387.81
MDL编号	MFCD00214312
PubChem化学物质编号	24278514
NACRES	NA.85

产品性质

质量水平	100
生物来源	synthetic
颜色	white to off-white
作用机制	DNA synthesis \| interferes enzyme \| inhibits
抗生素抗菌谱	Gram-negative bacteria Gram-positive bacteria
储存温度	−20℃
SMILES string	Cl.CCN1C=C(C(O)=O)C(=O)c2cc(F)c(N3CCNC(C)C3)c(F)c12
InChI	1S/C17H19F2N3O3.ClH/c1-3-21-8-11(17(24)25)16(23)10-6-12(18)15(13(19)14(10)21)22-5-4-20-9(2)7-22;/h6,8-9,20H,3-5,7H2,1-2H3,(H,24,25);1H
InChI key	KXEBLAPZMOQCKO-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302
危险分类	Acute Tox. 4 Oral
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves

364353

Fluorochem

Lomefloxacin Hydrochloride

95%

220元/1g; 286元/5g;

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基本信息

CAS Number	98079-52-8
MDL Number	MFCD00214312

安全信息

图形或危害标志
危险性说明	H302: Harmful if swallowed. H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation.
防范说明	P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing P264: Wash hands thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P271: Use only outdoors or in a well-ventilated area. P280: Wear . P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: . P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see . on this label). P330: Rinse mouth. P332 + P313: If skin irritation occurs: Get medical advice/ attention. P337 + P313: If eye irritation persists: Get medical advice/attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362: Take off contaminated clothing and wash before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to local regulations.