[登录] [免费注册]
试剂仪器网
位置:首页 > 资料中心 > 化工字典 > 98-96-4
关键词:       仅模糊查询
CAS: 98-96-4
分子式: C5H5N3O
分子量: 123.11
熔点: 188-191℃
中文名称: 
羧酸胺
吡嗪酰胺
英文名称: 
Pyrazine-carboxamide
β-Pyrazine-2-carboxamide
Pyrazine-2-carboxamide(δ-modification)
α-Pyrazinamid
Pyrazinamid
2-carbamyl pyrazine
aldinamid
aldinamide
d-50
eprazin
mk 56
nci-c01785
pyrazinamide
pyrazine carboxamide
pyrazine carboxylamide
pyrazineamide
pyrazinecarboxamide
pyrazinoic acid amide
tebrazid
展开更多英文名
用途: 抗结核病药。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
P822772MACKLIN吡嗪酰胺99%36元/5g;   60元/25g;   172元/100g;   630元/500g;   展开
储存:2~8 ℃
状态:白色结晶粉末
P795440MACKLINPyrazinamide10mM in DMSO428元/1ml;   展开
储存:-20°C
P0633TCIPyrazinamide>98.0%(HPLC)(N)555元/25G;   展开

基本信息

纯度/分析方法>98.0%(HPLC)(N)
分子式/分子量C5H5N3O = 123.12
外观与形状(20℃)固体
Reaxys-RN112306
PubChem物质ID87574793
SDBS (AIST Spectral DB)1084
Merck Index (14)7956
MDL编号MFCD00006132

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(with Total Nitrogen)min. 98.0 %
Melting point187.0 to 192.0 ℃
Solubility in hot Methanolalmost transparency

物性(参考值)

熔点190 ℃

相关法规

RTECS#UQ2275000
529540J&KPyrazinamide99%73元/5G;   155元/25G;   459元/100G;   展开

基本信息

分子式C5H5N3O
分子量123.12
熔点188-191
MDL编码MFCD00006132
Beilstein112306
Merck14,7956
EINECS 编号202-717-6

安全信息

防范说明P260
P262
WGK3
RTECSUQ2275000
TSCA
1585006USPPyrazinamideUnited States Pharmacopeia (USP) Reference Standard3231.47元/200 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C5H5N3O
分子量123.11
Beilstein112306
MDL编号MFCD00006132
PubChem化学物质编号329750868
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
mp189-191 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringNC(=O)c1cnccn1
InChI1S/C5H5N3O/c6-5(9)4-3-7-1-2-8-4/h1-3H,(H2,6,9)
InChI keyIPEHBUMCGVEMRF-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
P4050000PyrazinamideEuropean Pharmacopoeia (EP) Reference Standard1277.32元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 30 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C5H5N3O
分子量123.11
Beilstein112306
MDL编号MFCD00006132
PubChem化学物质编号329820195
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
mp189-191 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringNC(=O)c1cnccn1
InChI1S/C5H5N3O/c6-5(9)4-3-7-1-2-8-4/h1-3H,(H2,6,9)
InChI keyIPEHBUMCGVEMRF-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
P7136Sigma-AldrichPyrazinecarboxamide607.24元/10 G;   938.66元/25 G;   2780.13元/100 G;   展开

产品说明

应用

吡嗪酰胺在治疗上用作抗结核药。吡嗪酰胺用于形成聚合铜络合物,生成吡嗪甲酰胺支架,用作 FXs 抑制剂,以及作为分枝杆菌鉴定试剂盒的组分。用于研究肝脏毒性预防 和抗性机制 。

包装

10, 25, 100 g in poly bottle

生化/生理作用

吡嗪酰胺的活性部分是吡嗪酸(POA)。在 结核分枝杆菌 中,POA 视为在酸性 pH 下破坏膜能量并抑制膜输送功能。铁可增强吡嗪酰胺的抗结核活性 。经验证,吡嗪酰胺及其类似物可抑制纯化 FAS I 的活性。

其他说明

保存于密闭容器内,置于干燥通风处。

基本信息

经验(实验)分子式C5H5N3O
分子量123.11
Beilstein112306
EC 号202-717-6
MDL编号MFCD00006132
PubChem化学物质编号24278648
NACRESNA.85

产品性质

质量水平200
mp189-191 ℃ (lit.)
作用机制cell membrane | interferes
抗生素抗菌谱mycobacteria
SMILES stringNC(=O)c1cnccn1
InChI1S/C5H5N3O/c6-5(9)4-3-7-1-2-8-4/h1-3H,(H2,6,9)
InChI keyIPEHBUMCGVEMRF-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
PHR1576SupelcoPyrazinamidePharmaceutical Secondary Standard; Certified Reference Material1461.17元/500 MG;   展开

产品说明

一般描述

Pyrazinamide is an analog of nicotinamide. It is an antituberculosis drug and plays a vital role in reducing the duration of chemotherapy of tuberculosis.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Pyrazinamide may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography and multivariate spectrophotometry.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA4492 in the slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C5H5N3O
分子量123.11
Beilstein112306
EC 号202-717-6
MDL编号MFCD00006132
PubChem化学物质编号329823484
NACRESNA.24

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
包装pkg of 500 mg
technique(s)HPLC: suitable
gas chromatography (GC): suitable
mp189-191 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to BP 906
traceable to PhEur P4050000
traceable to USP 1585006
储存温度2-30℃
SMILES stringNC(=O)c1cnccn1
InChI1S/C5H5N3O/c6-5(9)4-3-7-1-2-8-4/h1-3H,(H2,6,9)
InChI keyIPEHBUMCGVEMRF-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
BP906PyrazinamideBritish Pharmacopoeia (BP) Reference Standard1870.39元/100 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C5H5N3O
分子量123.11
Beilstein112306
EC 号202-717-6
MDL编号MFCD00006132
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameBP
mp189-191 ℃ (lit.)
格式neat
储存温度2-8℃
SMILES stringNC(=O)c1cnccn1
InChI1S/C5H5N3O/c6-5(9)4-3-7-1-2-8-4/h1-3H,(H2,6,9)
InChI keyIPEHBUMCGVEMRF-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
8.21050Sigma-Aldrich2-Pyrazinecarboxamidefor synthesis559.89元/25 G;   展开

产品说明

分析说明

Assay (HPLC, area%): ≥ 98.0 % (a/a)
Melting range (lower value): ≥ 188 °C
Melting range (upper value): ≤ 191 °C
Identity (IR): passes test

基本信息

经验(实验)分子式C5H5N3O
分子量123.11
MDL编号MFCD00006132
EC索引号202-717-6

产品性质

质量水平200
测定≥98.0% (HPLC)
pH值(酸碱度)7 ( in H2O)
mp188-191 ℃
储存温度2-30℃
InChI1S/C5H5N3O/c6-5(9)4-3-7-1-2-8-4/h1-3H,(H2,6,9)
InChI keyIPEHBUMCGVEMRF-UHFFFAOYSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
068696FluorochemPyrazinamide97%242元/25g;   748元/100g;   6534元/1kg;   展开

基本信息

CAS Number98-96-4
MDL NumberMFCD00006132
Melting Point189-191℃

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
CAS号首数字顺序排列: 1 2 3 4 5 6 7 8 9