| CAS: | 97627-24-2 | |
| 分子式: | C13H12ClN3O | |
| 分子量: | 261.71 | |
| 中文名称: |
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| 用途: | N-[(1R)-4-[(Aminoiminomethyl)amino]-1-[[[(1R)-1-(4-hydroxyphenyl)ethyl]amino]carbonyl]butyl]-α-phenylbenzeneacetamide is an anticonvulsant agent with potential for the treatment of generalized tonic-c |
| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | |||
| N911651 | MACKLIN | N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea | 98% | 2162元/5mg; 3240元/10mg; 5511元/25mg; | 咨询 | ||
储存：-20°C，密闭，干燥 | |||||||
| HY-101708 | MCE | N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea,97627-24-2_MCE(MedChemExpress) | 429元/10 mM * 1 mL in DMSO; 160元/1 mg; 390元/5 mg; 652元/10 mg; 1287元/25 mg; 2075元/50 mg; 2912元/100 mg; | 咨询 | |||
MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。 N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylureaMCE 国际站：N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea 品牌：MedChemExpress (MCE) 货号：HY-101708 CAS 号：97627-24-2 生物活性： N-(2-氯-6-甲基苯基)-N'-4-吡啶基脲是一种抗惊厥药，具有治疗全身强直-阵挛性癫痫和部分性癫痫的潜力。 体内研究(In Vivo)：Compound shows anticonvulsant activity at 30 mg/kg in the initial tests with no signs of ataxia until 300 mg/kg. The activity seen with 30 mg/kg 37 is still present 4 h postdose. Compound is effective against seizures induced by maximal electroshock but does not protect mice from clonic seizures produced by the convulsant pentylenetetrazol. The overall pharmacological profile suggests that Compound would be of therapeutic use in the treatment of generalized tonic-clonic and partial seizures. Compound is selected for clinical trials[1]. MCE尚未独立确认这些方法的准确性。 仅供参考。 分子量：261.71 Formula：C13H12ClN3O 性状：固体 颜色：White to off-white 运输条件：美国大陆地区的室温；其他地区可能有所不同。 储存方式：粉末 -20°C 3年 Animal Administration [1]：Mice: Five mice are tested at each of three doses (30,100, and 300 mg/kg) and three times (0.5, 2, and 4 h). The mice are subjected to electrical current delivered through ear clips for 0.2 s (90 mA, 1-ms monophasic pulses at 100 Hz). This current strength is approximately 4 times that required to produce seizures in 99% of mice and reliably produce seizures in 100% of control mice. Prevention of tonic hind limb extension is taken as an anticonvulsant effect. Behavioral side effects are measured in mice[1]. MCE尚未独立确认这些方法的准确性。 仅供参考。 提供质量检测报告：Data Sheet、SDS、COA、HNMR、LCMS、产品使用指南 产品活性：N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea 是一种抗惊厥剂，有研究广泛强直和部分性发作挛性的潜质。 相关产品：HP-β-CD | BTTAA | Methyl-β-cyclodextrin | NAI-N3 | Neuromedin C (porcine) | Dansyl glutathione | 2-(Pyridyldithio)ethylamine hydrochloride | 24-Norursodeoxycholic acid | 2-Thio-PAF | Octanoylcarnitine chloride | EC330 | NAI-N3 (Standard) 热门产品线：抑制剂 | 稳定性同位素标记物 | 脂质 | 糖类 Trending products：Inhibitors | Isotope-Labeled Compounds | Lipids | Saccharides MCE 抑制剂: MedChemExpress 信号通路产品覆盖细胞凋亡、自噬、细胞周期与 DNA 损伤、表观遗传、GPCR/G 蛋白、免疫与炎症、JAK/STAT、MAPK/ERK、膜转运体与离子通道、代谢酶与蛋白酶、神经信号、NF-κB、PI3K/Akt/mTOR、PROTAC、蛋白酪氨酸激酶/受体酪氨酸激酶、干细胞/Wnt、TGF-β/Smad 及维生素 D/核受体等研究方向，为肿瘤、感染、炎症与免疫、神经系统疾病、代谢性疾病、心血管疾病和内分泌研究提供多维度的产品选择，助力客户发表文献超 80,000 篇。 相关产品可根据具体情况提供化学结构、作用靶点、生物活性、纯度、溶解度、体内外研究信息、参考文献及质量分析报告 (COA)等资料。 客户发表文献： 参考文献： 品牌介绍:
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