CAS 951-77-9; 2'-脱氧胞嘧啶核苷; 2'-deoxy-cytidine

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D806816

MACKLIN

2'-脱氧胞嘧啶核苷,水合物

99%

20元/500mg; 35元/1g; 51元/5g; 251元/25g; 889元/100g;

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储存：室温
状态：白色到灰白色粉末或晶体

D3583

TCI

2'-Deoxycytidine

>98.0%(T)(HPLC)

240元/1G; 915元/5G;

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基本信息

纯度/分析方法	>98.0%(T)(HPLC)
分子式/分子量	C₉H₁₃N₃O₄ = 227.22
外观与形状(20℃)	固体
Reaxys-RN	87567
PubChem物质ID	87559805
MDL编号	MFCD00006547

技术规格

Appearance	White to Almost white powder to crystal
Purity(HPLC)	min. 98.0 area%
Purity(Nonaqueous Titration)	min. 98.0 %
Specific rotation [a]20/D	+56.0 to +61.0 deg(C=1, H2O)

物性(参考值)

熔点	204 ℃
比旋光度 [α]D	59° (C=1,H2O)
水溶性	可溶

相关法规

RTECS#

HA3800000

206550

J&K

2'-Deoxycytidine

98%

126元/500MG; 228元/1g; 846元/5g;

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基本信息

分子式	C₉H₁₃N₃O₄
分子量	227.22
熔点	209-211
MDL编码	MFCD00006547
Beilstein	87567
EINECS 编号	213-454-1

安全信息

防范说明	P262
WGK	3
RTECS	HA3800000

D3897

Sigma-Aldrich

2′-Deoxycytidine

≥99% (HPLC)

684.83元/100 MG; 722.13元/250 MG; 936.63元/500 MG; 1603.19元/1 G; 5441.41元/5 G;

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产品说明

一般描述

2′-Deoxycytidine (deoxyC) is one of the deoxynucleosides containing cytosine as the nucleobase. It is found in the blood, feces, and urine.

应用

2′-Deoxycytidine has been used:

as a substrate for Trypanosoma brucei cytidine deaminase (TbCDA) to measure its activity
as a standard in the isolation and quantification of metabolite levels in murine tumor interstitial fluid by liquid chromatography-mass spectrometry (LC–MS)
to study the role of autophagy in response to oncogenes and DNA replication stress

包装

1, 5 g in poly bottle
100, 250, 500 mg in poly bottle

生化/生理作用

2′-Deoxycytidine (deoxyC) forms dCTP upon phosphorylation which is used to synthesis DNA via various DNA polymerases or reverse transcriptases. DeoxyC is the substrate for deoxycytidine deaminase (EC 3.5.4.14) which converts it into 2′-deoxyuridine. DeoxyC is phosphorylated to the nucleotide dCMP by the enzyme deoxycytidine kinase (DCK). DeoxyC serves as a potential head and neck cancer marker.

基本信息

经验(实验)分子式	C₉H₁₃N₃O₄
分子量	227.22
Beilstein	87567
EC 号	213-454-1
MDL编号	MFCD00006547
PubChem化学物质编号	24893793
NACRES	NA.51

产品性质

质量水平	200
生物来源	synthetic (organic)
测定	≥99% (HPLC)
形式	powder
溶解性	water: 50 mg/mL, clear, colorless to very faintly yellow
储存温度	−20℃
SMILES string	NC1=NC(=O)N(C=C1)[C@H]2C[C@H](O)[C@@H](CO)O2
InChI	1S/C9H13N3O4/c10-7-1-2-12(9(15)11-7)8-3-5(14)6(4-13)16-8/h1-2,5-6,8,13-14H,3-4H2,(H2,10,11,15)/t5-,6+,8+/m0/s1
InChI key	CKTSBUTUHBMZGZ-SHYZEUOFSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)

211296

Fluorochem

4-Amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one

95%

220元/1g; 440元/5g; 748元/10g; 1276元/25g;

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基本信息

CAS Number	951-77-9
MDL Number	MFCD00006547
Boiling Point	368.93℃
Melting Point	192-202℃
Density	1.3171

安全信息

图形或危害标志
危险性说明	H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation.
防范说明	P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing . P264: Wash hands thoroughly after handling. P271: Use only outdoors or in a well-ventilated area. P280: Wear . P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.. P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see relevant procedures. on this label). P332 + P313: If skin irritation occurs: Get medical advice/ attention. P337 + P313: If eye irritation persists: Get medical advice/attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362: Take off contaminated clothing and wash before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to in accordance with local regulation .