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CAS: 950-99-2
分子式: C14H20O2
分子量: 220.31
熔点: 89-91℃
中文名称: 
3,4-二氢-2,2,5,7,8-五甲基-2H-1-苯并吡喃-6-酚
英文名称: 
2H-1-Benzopyran-6-ol,3,4-dihydro-2,2,5,7,8-pentamethyl-
3,4-dihydro-2,2,5,7,8-pentamethyl-2H-1-Benzopyran-6-ol
2,2,5,7,8-pentamethyl-1-hydroxychroman
2,2,5,7,8-pentamethyl-6-chromanol
用途: 2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) is the anti-oxidant moiety of vitamin E. 2,2,5,7,8-Pentamethyl-6-Chromanol has potent androgen receptor (AR) signaling modulation and anti-cancer activity.
推荐供应商
货号品牌产品名称规格包装、参考价格详情
P913197MACKLIN2,2,5,7,8-Pentamethyl-6-Chromanol98%786元/100mg;   展开
储存:-20°C,密闭,干燥
430676Sigma-Aldrich2,2,5,7,8-Pentamethyl-6-chromanol97%625.24元/5 G;   2434.6元/25 G;   展开

产品说明

一般描述

2,2,5,7,8-Pentamethyl-6-chromanol has been reported as an vitamin E model compound. It undergoes oxidation in presence of various alcohols, ranging from methanol to cholesterol, affords 5-alkoxymethyl-2,2,7,8-tetramethyl-6-chromanols. Antioxidant moiety of vitamin E, 2,2,5,7,8-pentamethyl-6-chromanol (PMCol), is reported to have antiandrogen activity in prostate carcinoma cells.

应用

2,2,5,7,8-Pentamethyl-6-chromanol is the suitable reagent used for the quantitative analysis of α-tocopherol by plasma-based gas chromatography/tandem mass spectrometry (GC/MS/MS) using a tabletop quadrupole ion trap mass spectrometer. It may be employed as α-tocopherol model compound and on oxidation by t-butyl hydroperoxide in chloroform, in the presence of alcohol, affords 5-alkoxymethyl-2,2,7,8-tetramethyl-6-chromanol. It may be used as internal standard for the determination of α- and γ-tocopherol in the rabbit serum and liver by HPLC.

包装

5, 25 g in poly bottle

基本信息

经验(实验)分子式C14H20O2
分子量220.31
MDL编号MFCD00210347
PubChem化学物质编号24866935

产品性质

质量水平100
测定97%
mp89-91 ℃ (lit.)
SMILES stringCc1c(C)c2OC(C)(C)CCc2c(C)c1O
InChI1S/C14H20O2/c1-8-9(2)13-11(10(3)12(8)15)6-7-14(4,5)16-13/h15H,6-7H2,1-5H3
InChI keySEBPXHSZHLFWRL-UHFFFAOYSA-N
Gene Informationhuman ... AR(367)

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
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