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CAS: 948841-07-4
分子式: C15H14BrNOS
分子量: 336.25
英文名称: 
tb5
(2e)-1-(5-bromothiophen-2-yl)-3-[4-(dimethylamino)phenyl]prop-2-en-1-one
用途: TB5 是具有有效性,选择性和可逆性的 hMAO-B 抑制剂,Ki 值为 0.11±0.01 μM。
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货号品牌产品名称规格包装、参考价格详情
T876201MACKLINTB5 98%190元/2mg;   284元/5mg;   展开
储存:2-8℃
T795169MACKLINTB510mM in DMSO208元/1ml;   展开
储存:-20°C
SML2144Sigma-AldrichTB5≥98% (HPLC)1283.77元/5 MG;   5192.9元/25 MG;   展开

产品说明

生化/生理作用

TB5 is a potent and selective reversible inhibitor of monoamine oxidase B (MAOB) with a Ki value of 110 nM. A reversible inhibitor should have an advantage over irreversible inhibitors such as selegiline in limiting side effects. Parallel artificial membrane permeation (PAMPA) assays indicated TB5 should be able to cross the blood–brain barrier. TB5 was found nontoxic to cells.

基本信息

经验(实验)分子式C15H14BrNOS
分子量336.25
MDL编号MFCD30718167
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 yellow to orange
溶解性DMSO: 2 mg/mL, clear
储存温度2-8℃
SMILES stringCN(C)C(C=C1)=CC=C1/C=C/C(C2=CC=C(Br)S2)=O

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
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