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CAS: 948-65-2
分子式: C14H11N
分子量: 193.25
沸点: 250℃(10
熔点: 188-191℃
中文名称: 
2-苯基-1H-吲哚
2-苯基吲哚
α-苯基吲哚
英文名称: 
2-phenyl indole
1H-Indole,2-phenyl-
-Phenylindole
2-phenyl-1H-Indole
2-phenyl-indol
2-phenyl-1h-indol
2-phenylindole
alpha-phenylindole
stabilizer i
性质描述: 片状结晶。熔点189℃,沸点>360℃,250℃(1.33kPa)。溶于醚、苯、乙酸、氯仿和热二硫化碳,微溶于热水。能升华,微随水蒸气挥发。在空气中渐变绿色,似吲哚气味。
生产方法: 由苯肼与苯乙酮缩合后,再在氯化锌存在下闭环而制得2-苯基吲哚。除上述的Fisher法外,可将溴代苯乙酮与过量的苯胺加热反应,或将N-(2-甲基苯基)苯甲酰胺和乙醇钠隔绝空气于360-380℃加热,都可制得2-苯基吲哚。原料消耗定额:苯乙酮(98%)735kg/t、苯肼(游离100%)675kg/t、二甲苯900kg/t、冰醋酸15kg/t、氯化锌1230kg/t、盐酸(30%)810kg/t。
用途: 该品主要作为阳离子染料中间体,用于生产阳离子橙2GL、阳离子红BL、阳离子红2GL,用于染料生产时往往先经甲基化,进一步制成N-甲基-2-苯基吲哚。甲基化剂为硫酸二甲酯,反应在氯苯溶剂中进行,在60-65℃反应,收率为83.5%。2-苯基吲哚也用作乳液法聚氯乙烯的热稳定剂。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
P816283MACKLIN2-苯基吲哚99%29元/10g;   59元/50g;   220元/250g;   688元/1kg;   2560元/5kg;   展开
储存:室温
状态:白色到浅黄色到米黄色粉末
P0188TCI2-Phenylindole>98.0%(GC)235元/25G;   575元/250G;   展开

基本信息

纯度/分析方法>98.0%(GC)
分子式/分子量C14H11N = 193.25
外观与形状(20℃)固体
Reaxys-RN132356
PubChem物质ID87574437
SDBS (AIST Spectral DB)3207
MDL编号MFCD00005608

技术规格

AppearanceWhite to Orange to Green powder to crystal
Purity(GC)min. 98.0 %
Melting point188.0 to 193.0 ℃
Solubility in Methanolalmost transparency

物性(参考值)

熔点192 ℃
297863J&K2-Phenylindole99%60元/5G;   137元/25G;   399元/100G;   1895元/500G;   展开

基本信息

分子式C14H11N
分子量193.24
熔点188-191
沸点250
MDL编码MFCD00005608
Beilstein132356
EINECS 编号213-436-3

安全信息

图形或危害标志
提示语Danger
危险说明H315
H318
H335
H413
防范说明P261
P280
P305+P351+P338
WGK3
RTECSNM1272500
TSCA
B23674Alfa Aesar2-Phenylindole95%609元/50g;   1198元/250g;   展开

基本信息

MDL
MFCD00005608

EINECS
213-436-3

分子式
C14H11N

分子量
193.25

熔点
189-190°

沸点
250°/10mm

形态
Powder

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H318-H335
Causes skin irritation.Causes serious eye damage.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
37/38-41
Irritating to respiratory system and skin.Risk of serious damage to eyes.

安全等级
26-37/39-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable gloves and eye/face protection.This material and its container must be disposed of as hazardous waste

RTECS
NM1272500

TSCA

P26600Sigma-Aldrich2-Phenylindoletechnical grade, 95%311.16元/5 G;   524.78元/100 G;   展开

产品说明

应用

作为以下制备反应的反应物:

  • 通过碘催化的Markovnikov加成反应制备的氧吡咯烷类似物
  • 色氨酸双加氧酶抑制剂吡啶基-乙烯基-吲哚类化合物可作为潜在的抗癌免疫调节剂
  • 有机发光二极管(OLED)
  • 抗炎药
  • 潜在的环氧合酶1(COX-1)/环氧合酶2(COX-2)抑制剂
  • 癌症和疟疾治疗剂
  • 抗真菌和抗菌剂
  • 荧光探针

作为以下反应的反应物:
  • 二氟羟基化反应†
  • Mannich型反应†

包装

5, 100 g in glass bottle

基本信息

经验(实验)分子式C14H11N
分子量193.24
EC 号213-436-3
MDL编号MFCD00005608
PubChem化学物质编号24898346
NACRESNA.22

产品性质

等级technical grade
质量水平100
测定95%
bp250 ℃/10 mmHg (lit.)
mp188-190 ℃ (lit.)
SMILES stringc1ccc(cc1)-c2cc3ccccc3[nH]2
InChI1S/C14H11N/c1-2-6-11(7-3-1)14-10-12-8-4-5-9-13(12)15-14/h1-10,15H
InChI keyKLLLJCACIRKBDT-UHFFFAOYSA-N

安全信息

象形图GHS05GHS07
警示用语:Danger
危险声明H315 - H318 - H335 - H413
预防措施声明P273 - P280 - P302 + P352 - P305 + P351 + P338 + P310
危险分类Aquatic Chronic 4 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
221612Fluorochem2-Phenyl-1H-indole95%220元/25g;   550元/100g;   1056元/250g;   展开

基本信息

CAS Number948-65-2
MDL NumberMFCD00005608
Melting Point185-193℃

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H332: Harmful if inhaled.
H335: May cause respiratory irritation.
H413: May cause long lasting harmful effects to aquatic life.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P273: Avoid release to the environment.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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