CAS 940929-33-9; sb743921 hydrochloride

CAS:

940929-33-9

分子式:

C₃₁H₃₃N₂O₃·HCl

分子量:

553.52

英文名称:

sb743921 hydrochloride

n-(3-aminopropyl)-n-[(1R)-1-[7-chloro-4-oxo-3-(phenylmethyl)-4h-1-benzopyran-2-yl]-2-methylpropyl]-4-methylbenzamide hydrochloride

用途:

SB743921是一种kinesin spindle protein (KSP)（纺锤体驱动蛋白）抑制剂，Ki为0.1 nM，对MKLP1， Kin2， Kif1A， Kif15， KHC， Kif4和CENP-E几乎没有亲和力。Phase 1/2。

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

详情

S797285

MACKLIN

SB743921 HCl

10mM in DMSO

1686元/1ml;

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储存：-20°C

S872275

MACKLIN

SB743921 HCl

95%

367元/1mg; 1050元/5mg; 3850元/25mg; 7950元/100mg;

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储存：-20℃
状态：粉末

SML1121

Sigma-Aldrich

SB743921 hydrochloride

≥98% (HPLC)

2394.05元/5 MG; 9587.79元/25 MG;

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产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

SB743921 is an inhibitor of kinesin spindle protein (KSP) with Ki of 0.1 nM, almost no affinity to MKLP1, Kin2, Kif1A, Kif15, KHC, Kif4, and CENP-E.

特点和优势

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

基本信息

经验(实验)分子式	C₃₁H₃₃ClN₂O₃ · HCl
分子量	553.52
MDL编号	MFCD18385010
PubChem化学物质编号	329825661

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	H₂O: 5 mg/mL, clear
储存温度	−20℃
SMILES string	CC(C)[C@@H](N(CCCN)C(C1=CC=C(C)C=C1)=O)C2=C(CC3=CC=CC=C3)C(C4=C(O2)C=C(Cl)C=C4)=O.Cl
InChI	1S/C31H33ClN2O3.ClH/c1-20(2)28(34(17-7-16-33)31(36)23-12-10-21(3)11-13-23)30-26(18-22-8-5-4-6-9-22)29(35)25-15-14-24(32)19-27(25)37-30;/h4-6,8-15,19-20,28H,7,16-18,33H2,1-3H3;1H/t28-;/m1./s1
InChI key	MLMZVWABFOLFGV-LNLSOMNWSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable