CAS 94055-76-2; sulfonium, (3-((4-(3-ethoxy-2-hydroxypropoxy)phenyl)amino)-3-oxopropyl)dimethyl

CAS:

94055-76-2

分子式:

C₂₃H₃₃NO₇S₂

分子量:

499.64

英文名称:

sulfonium, (3-((4-(3-ethoxy-2-hydroxypropoxy)phenyl)amino)-3-oxopropyl)dimethyl

(+-)-(2-(4-(3-ethoxy-2-hydroxypropoxy)phenyl)carbamoyl)ethyldimethylsulf oniu

m p-tosylate

ipd 1151t

ipd-1151t

suplatast tosilate

用途:

Th2 cytokine inhibitor that attenuates IL-2, IL-5 and IL-13 production and has no effect on IFN-γ production. Acts as an immunoregulator that suppresses IgE production, eosinophil infiltration and histamine release. Shows antiasthmatic, anti-inflammatory and antifibrotic activity in vivo and is orally active.

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

详情

S864183

MACKLIN

Suplatast Tosylate

≥97%

273元/100mg; 868元/500mg;

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储存：室温
状态：白色到浅黄色到浅橙色粉末到晶体

S794849

MACKLIN

Suplatast Tosylate

10mM in DMSO

299元/1ml;

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储存：-20°C

S0875

TCI

Suplatast Tosylate

>98.0%(HPLC)(N)

380元/100MG; 1845元/1G;

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基本信息

纯度/分析方法	>98.0%(HPLC)(N)
分子式/分子量	C₂₃H₃₃NO₇S₂ = 499.64
外观与形状(20℃)	固体
Reaxys-RN	7510580
PubChem物质ID	135727338
Merck Index (14)	9003
MDL编号	MFCD00867604

技术规格

Appearance	White to Light yellow to Light orange powder to crystal
Purity(HPLC)	min. 98.0 area%
Purity(with Total Nitrogen)	min. 98.0 %

物性(参考值)

熔点	87 ℃
水溶性	完全溶解
溶解性(易溶于)	甲醇
溶解性(可溶于)	乙醇

相关法规

RTECS#

WR7906000

S4701

Sigma-Aldrich

Suplatast Tosylate

≥98% (HPLC)

3261.46元/50 MG;

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产品说明

应用

Suplatast tosylate may be used in immune-signaling studies.

包装

10, 50 mg in glass bottle

生化/生理作用

Suplatast tosylate is a dimethylsulfonium compound downregulates the expression of histamine H₁ receptor gene, suppresses the activity of histidine decarboxylase and regulates IL-4 mRNA. It inhibits the release of histamines and regulates the production of IgE.^1,2 Suplatast tosylate is effective in the treatment of mild-to-moderate persistent asthma in children.³
Suplatast tosylate is an anti-allergy, cytokine modulator.

基本信息

经验(实验)分子式	C₁₆H₂₆SNO₄ · C₇H₇SO₃
分子量	499.64
MDL编号	MFCD00867604
PubChem化学物质编号	329824551
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to off-white
溶解性	DMSO: >20 mg/mL
储存温度	room temp
SMILES string	Cc1ccc(cc1)S([O-])(=O)=O.CCOCC(O)COc2ccc(NC(=O)CC[S+](C)C)cc2
InChI	1S/C16H25NO4S.C7H8O3S/c1-4-20-11-14(18)12-21-15-7-5-13(6-8-15)17-16(19)9-10-22(2)3;1-6-2-4-7(5-3-6)11(8,9)10/h5-8,14,18H,4,9-12H2,1-3H3;2-5H,1H3,(H,8,9,10)
InChI key	RYVJQEZJUFRANT-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable