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CAS: 94-20-2
分子式: C10H13ClN2O3S
分子量: 276.75
中文名称: 
氯磺丙脲
对氯苯磺酰丙脲
N'-丙基-N'-对氯苯磺酰基脲
特泌胰
英文名称: 
1-((p-chlorophenyl)sulfonyl)-3-propyl-ure
1-(p-chlorobenzenesulfonyl)-3-propylurea
1-(p-chlorophenylsulfonyl)-3-propylurea
1-p-chlorophenyl-3-(propylsulfonyl)urea
1-propyl-3-(p-chlorobenzenesulfonyl)urea
4-chloro-4-((propylamino)carbonyl)benzenesulfonamide
4-chloro-n-[(propylamino)carbonyl]benzenesulfonamide
adiaben
asucrol
4-chloro-n-((propylamino)carbonyl)-benzenesulfonamid
4-chloro-n-[(propylamino)carbonyl]-benzenesulfonamid
bioglumin
catanil
chlorodiabina
chloronase
chloropropamide
chlorpropamid
chlorpropamide
clorpropamide
diabaril
diabechlor
diabenal
diabenese
diabeneza
diabet-pages
diabetoral
diabexan
diabinese
glisema
meldian
melitase
mellinese
millinese
n-(4-chlorophenylsulfonyl)-n'-propylurea
n-(p-chlorobenzenesulfonyl)-n'-propylurea
n-propyl-n'-(p-chlorobenzenesulfonyl)urea
n-propyl-n'-p-chlorphenylsulfonylcarbamide
nci-c01752
oradian
p 607
prodiaben
u-3818
u-9818
1-((p-chloropenyl)sulfonyl)-3-propyl-ure
4-Chloro-N-[(propylamino)carbonyl]benzene-sul-fonamide
1-[(p-Chlorophenyl)sulfonyl]-3-propy-lurea
展开更多英文名
性质描述: 白色结晶性粉末。熔点127-129℃。易溶于氯仿和丙酮,略溶于乙醚、苯、在pH为6的水中溶解度为2.2mg/ml,在pH7.3的水中不溶。无臭,无味。
生产方法: 由对氯苯磺酰胺与丁酰胺反应而得对氯苯磺酰丙脲钠盐。再用盐酸酸化、精制而得成品。另一种方法是以对氯苯磺酰胺、异氰酸丙酯、三乙胺为原料。
用途: 磺脲类口服降血糖药。作用强而持久,主要选择性地作用于胰岛-β-细胞,促进胰岛的分泌,使血糖降低。用于糖尿病。氯磺丙脲具有比较大的副作用,所以该药的使用量有逐年减少的趋势。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
C795432MACKLIN氯磺丙脲10mM in DMSO383元/1ml;   展开
储存:-20°C
C1220TCI1-(4-Chlorophenylsulfonyl)-3-propylurea>99.0%(T)640元/25G;   展开

基本信息

纯度/分析方法>99.0%(T)
分子式/分子量C10H13ClN2O3S = 276.74
外观与形状(20℃)固体
Reaxys-RN2218363
PubChem物质ID87566242
SDBS (AIST Spectral DB)10567
Merck Index (14)2186
MDL编号MFCD00079004

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Neutralization titration)min. 99.0 %
Melting point127.0 to 131.0 ℃
Solubility in Acetonealmost transparency

物性(参考值)

熔点128 ℃

安全信息

信号词警告
危险性说明H303 : 吞咽可能有害。
防范说明P312 : 如感觉不适,呼叫急救中心/医生。

相关法规

RTECS#YS6650000
166341J&KChlorpropamide99%568元/25G;   1870元/100G;   展开

基本信息

分子式C10H13ClN2O3S
分子量276.74
熔点127-130
MDL编码MFCD00079004
Beilstein2218363
Merck14,2186
EINECS 编号202-314-5

安全信息

图形或危害标志
提示语Warning
危险说明H312
H332
H351
防范说明P280
WGK3
RTECSYS6650000
TSCA
PHR1284SupelcoChlorpropamidePharmaceutical Secondary Standard; Certified Reference Material855.65元/1 G;   展开

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Chlorpropamide belongs to the sulfonylurea class of drugs and is found to be clinically effective in the treatment of Diabetes mellitus (DM). Its mode of action involves the stimulation of insulin release from the β-cells of the pancreas in response to a glucose load. It helps in increasing the number of insulin receptors, thereby enhancing the effect of insulin on the liver and promotes peripheral glucose utilization.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Chlorpropamide may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using capillary zone elctrophoresis technique and spectrophotometric technique.

分析说明

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA0019 in the slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C10H13ClN2O3S
分子量276.74
EC 号202-314-5
MDL编号MFCD00079004
PubChem化学物质编号329823279
NACRESNA.24

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to PhEur C1905000
traceable to USP 1126009
储存温度2-30℃
SMILES stringCCCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1
InChI1S/C10H13ClN2O3S/c1-2-7-12-10(14)13-17(15,16)9-5-3-8(11)4-6-9/h3-6H,2,7H2,1H3,(H2,12,13,14)
InChI keyRKWGIWYCVPQPMF-UHFFFAOYSA-N
Gene Informationhuman ... ABCC8(6833), KCNJ11(3767)

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H302 - H361f - H373
预防措施声明P201 - P301 + P312 + P330 - P308 + P313
危险分类Acute Tox. 4 Oral - Repr. 2 - STOT RE 2
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
C1905000ChlorpropamideEuropean Pharmacopoeia (EP) Reference Standard1560.25元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C10H13ClN2O3S
分子量276.74
MDL编号MFCD00079004
PubChem化学物质编号329774914
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCCCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1
InChI1S/C10H13ClN2O3S/c1-2-7-12-10(14)13-17(15,16)9-5-3-8(11)4-6-9/h3-6H,2,7H2,1H3,(H2,12,13,14)
InChI keyRKWGIWYCVPQPMF-UHFFFAOYSA-N
Gene Informationhuman ... ABCC8(6833), KCNJ11(3767)

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H302 - H361f - H373
预防措施声明P201 - P301 + P312 + P330 - P308 + P313
危险分类Acute Tox. 4 Oral - Repr. 2 - STOT RE 2
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
C1290SupelcoChlorpropamideanalytical standard, ≥97%1420.95元/25 G;   展开

产品说明

一般描述

Chlorpropamide is a drug that belongs to the sulfonylurea family. It is an effective candidate in the treatment of diabetes insipidus.

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

包装

25 g in poly bottle

基本信息

经验(实验)分子式C10H13ClN2O3S
分子量276.74
EC 号202-314-5
MDL编号MFCD00079004
PubChem化学物质编号329774748
NACRESNA.24

产品性质

等级analytical standard
质量水平100
测定≥97%
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)forensics and toxicology
pharmaceutical (small molecule)
格式neat
SMILES stringCCCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1
InChI1S/C10H13ClN2O3S/c1-2-7-12-10(14)13-17(15,16)9-5-3-8(11)4-6-9/h3-6H,2,7H2,1H3,(H2,12,13,14)
InChI keyRKWGIWYCVPQPMF-UHFFFAOYSA-N
Gene Informationhuman ... ABCC8(6833), ALB(213), EPHX2(2053), KCNJ1(3758), KCNJ11(3767)
mouse ... Ephx2(13850)

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H302 - H361f - H373
预防措施声明P201 - P301 + P312 + P330 - P308 + P313
危险分类Acute Tox. 4 Oral - Repr. 2 - STOT RE 2
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
1126009USPChlorpropamideUnited States Pharmacopeia (USP) Reference Standard3231.47元/200 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C10H13ClN2O3S
分子量276.74
MDL编号MFCD00079004
PubChem化学物质编号329749341
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringCCCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1
InChI1S/C10H13ClN2O3S/c1-2-7-12-10(14)13-17(15,16)9-5-3-8(11)4-6-9/h3-6H,2,7H2,1H3,(H2,12,13,14)
InChI keyRKWGIWYCVPQPMF-UHFFFAOYSA-N
Gene Informationhuman ... ABCC8(6833), KCNJ11(3767)

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H312 + H332 - H351
预防措施声明P261 - P280
危险分类Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Carc. 2
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
242203Fluorochem4-Chloro-N-(propylcarbamoyl)benzenesulfonamide95%330元/10g;   682元/25g;   1892元/100g;   展开

基本信息

CAS Number94-20-2
MDL NumberMFCD00079004
Melting Point128℃

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: .
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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