CAS 93602-66-5; adenosine-3',5'-cyclic monophosphorothioate,sp-isomer(sp-camps),triethyl ammonium

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产品名称

规格

包装、参考价格

详情

425301

J&K

Adenosine 3',5'-cyclic monophosphothioate Sp-isomer triethylammonium salt

4235元/1MG;

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基本信息

分子式	C₁₀H₁₁N₅O₅PS·C₆H₁₆N
分子量	446.46
MDL编码	MFCD01459901
存储条件	Freezer -20℃

安全信息

防范说明	P262
WGK	3

A166

Sigma-Aldrich

Sp-Adenosine 3′,5′-cyclic monophosphorothioate triethylammonium salt hydrate

≥98% (HPLC), solid

2523.26元/1 MG; 8014.88元/5 MG; 12074.4元/10 MG;

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产品说明

包装

1, 5, 10 mg in glass bottle

生化/生理作用

Sp-Diastereomer of adenosine 3′,5′-cyclic monophosphorothioate is a potent, membrane-permeable activator of cAMP dependent protein kinase I and II that mimics the effects of cAMP as a second messenger in numerous systems while being resistant to cyclic nucleotide phosphodiesterases; exhibits greater specificity and affinity than forskolin and cAMP analogs such as dibutyryl-cAMP.

基本信息

经验(实验)分子式	C₁₀H₁₁N₅O₅PS · C₆H₁₆N · xH₂O
分子量	446.46 (anhydrous basis)
MDL编号	MFCD01459901
PubChem化学物质编号	24890576
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	solid
旋光性	[α]22/D −25.43°, c = 0.99 in H₂O(lit.)
颜色	white
溶解性	H₂O: soluble
web metadata keyword.default	Sp-3′,5′-cAMPS; A166; cAMPS-Sp; Sp-cAMPS; Adenosine 3′,5′-Cyclic-monophosphothioate, Sp-Isomer; phosphothioate; cAMP analogue; axial exocyclic; diastereomer; stereoselective agonist; stereoselective antagonist; camp dependent kinase; camp dependent protein kinase; forskolin; DBcAMP; dibutyryl
储存温度	−20℃
SMILES string	CCN(CC)CC.Nc1ncnc2n(cnc12)[C@@H]3O[C@@H]4CO[P@@](S)(=O)O[C@H]4[C@H]3O
InChI	1S/C10H12N5O5PS.C6H15N/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(19-10)1-18-21(17,22)20-7;1-4-7(5-2)6-3/h2-4,6-7,10,16H,1H2,(H,17,22)(H2,11,12,13);4-6H2,1-3H3/t4-,6-,7-,10-,21+;/m1./s1
InChI key	OXIPZMKSNMRTIV-BIQAKYJPSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)