CAS 93479-97-1; 格列美脲; 1h-pyrrole-1-carboxamide, 2,5-dihydro-3-ethyl-4-methyl-n-(2-(4-(((((4-methylcyc

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

G798166

MACKLIN

格列美脲

10mM in DMSO

473元/1ml;

咨询

储存：-20°C

G838237

MACKLIN

格列美脲

98 % HPLC, solid

31元/50mg; 83元/250mg; 175元/1g; 547元/5g; 1999元/25g;

咨询

储存：室温
状态：白色到灰白色固体

G0395

TCI

Glimepiride

>98.0%(T)(HPLC)

560元/1G; 1750元/5G;

咨询

基本信息

纯度/分析方法	>98.0%(T)(HPLC)
分子式/分子量	C₂₄H₃₄N₄O₅S = 490.62
外观与形状(20℃)	固体
Reaxys-RN	7731873
PubChem物质ID	160870906
Merck Index (14)	4440
MDL编号	MFCD00878417

技术规格

Appearance	White to Almost white powder to crystal
Purity(HPLC)	min. 98.0 area%
Purity(Neutralization titration)	min. 98.0 %
Melting point	202.0 to 206.0 ℃

物性(参考值)

熔点	204 ℃
水溶性	不溶
溶解性(可溶于)	二甲基甲酰胺
溶解度(极微溶)	二氯甲烷
溶解性(不溶于)	甲醇,乙醇

安全信息

图形或危害标志
信号词	警告
危险性说明	H361 : 怀疑对生育能力或胎儿造成伤害。
防范说明	P501 : 将内装物/容器送到批准的废物处理厂处理。 P202 : 在阅读并明了所有安全措施前切勿搬动。 P201 : 使用前取得专用说明。 P280 : 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P308 + P313 : 如接触到或有疑虑：求医/就诊。 P405 : 存放处须加锁。

相关法规

RTECS#

UX9363950

942069

J&K

Glimepiride

98%

950元/25MG; 1596元/100MG;

咨询

基本信息

分子式	C₂₄H₃₄N₄O₅S
分子量	490.62
熔点	212-215
MDL编码	MFCD00878417
存储条件	Freezer -20℃

安全信息

图形或危害标志
提示语	Warning
危险说明	H361
防范说明	P280

R10987

Alfa Aesar

Glimepiride Standard solution

100ppm

210元/1ml;

咨询

安全信息

危险等级
3

R12036

Alfa Aesar

Glimepiride,1000ppm

440元/1ml;

咨询

安全信息

危险等级
3

PHR1617

Supelco

Glimepiride

Pharmaceutical Secondary Standard; Certified Reference Material

2391.32元/1 G;

咨询

产品说明

一般描述

格列美脲是一种抗糖尿病药，属于磺酰脲类。它通常用于治疗2型糖尿病。
用于质量控制的药品二级标准品，为制药实验室和制造商提供了一种方便且经济的替代方案，可用于内部工作标准品的制备。

应用

格列美脲可用作药物参考标准品，用于通过高效液相色谱法测定散装药物和药物制剂中的分析物。
这些二级标准品是合格的有证标准物质。它们适用用于于多种分析应用，包括但不限于药物释放检测、用于定性和定量分析的药物方法开发、食品和饮料质量控制检测以及其他校准要求。

分析说明

这些二级标准品可溯源到USP、EP和BP一级标准品。

其他说明

该认证参考物质(CRM)根据ISO 17034 和 ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。

附注

欲查看此物质的分析证书样本，请在下面的对话框中输入LRAb7813。这只是一个示例证书，可能与您收到的批次不符。

基本信息

经验(实验)分子式	C₂₄H₃₄N₄O₅S
分子量	490.62
NACRES	NA.24

产品性质

质量水平	300
等级	certified reference material pharmaceutical secondary standard
CofA	current certificate can be downloaded
包装	pkg of 1 g
technique(s)	HPLC: suitable gas chromatography (GC): suitable
application(s)	pharmaceutical (small molecule)
格式	neat
药典可追溯性	traceable to BP 1144 traceable to PhEur Y0000515 traceable to USP 1292303
储存温度	2-30℃
InChI	1S/C24H34N4O5S/c1-4-21-17(3)15-28(22(21)29)24(31)25-14-13-18-7-11-20(12-8-18)34(32,33)27-23(30)26-19-9-5-16(2)6-10-19/h7-8,11-12,16,19H,4-6,9-10,13-15H2,1-3H3,(H,25,31)(H2,26,27,30)
InChI key	WIGIZIANZCJQQY-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H361
预防措施声明	P201 - P202 - P280 - P308 + P313 - P405 - P501
危险分类	Repr. 2
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

Y0000515

Glimepiride

European Pharmacopoeia (EP) Reference Standard

1277.32元/ ;

咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

格列美脲目前用于治疗 2 型糖尿病。

生化/生理作用

格列美脲是一种有效的心肌梗死 K_ATP 通道阻断剂，被吡那地尔激活，IC₅₀ 值为 6.8 nM。

包装

Unit quantity: 110 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式	C₂₄H₃₄N₄O₅S
分子量	490.62
MDL编号	MFCD00878417
PubChem化学物质编号	329830996
NACRES	NA.24

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	EDQM
application(s)	pharmaceutical (small molecule)
格式	neat
储存温度	2-8℃
SMILES string	CCC1=C(C)CN(C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)N[C@H]3CC[C@H](C)CC3)C1=O
InChI	1S/C24H34N4O5S/c1-4-21-17(3)15-28(22(21)29)24(31)25-14-13-18-7-11-20(12-8-18)34(32,33)27-23(30)26-19-9-5-16(2)6-10-19/h7-8,11-12,16,19H,4-6,9-10,13-15H2,1-3H3,(H,25,31)(H2,26,27,30)/t16-,19-
InChI key	WIGIZIANZCJQQY-RUCARUNLSA-N
Gene Information	human ... ABCC8(6833), KCNJ11(3767)

安全信息

象形图
警示用语：	Warning
危险声明	H361
预防措施声明	P201 - P202 - P280 - P308 + P313 - P405 - P501
危险分类	Repr. 2
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

Y0000516

Glimepiride for system suitability

European Pharmacopoeia (EP) Reference Standard

1277.32元/ ;

咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

格列美脲目前用于治疗 2 型糖尿病。

生化/生理作用

格列美脲是一种有效的心肌梗死 K_ATP 通道阻断剂，被吡那地尔激活，IC₅₀ 值为 6.8 nM。

包装

Unit quantity: 0.012 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式	C₂₄H₃₄N₄O₅S
分子量	490.62
MDL编号	MFCD00878417
PubChem化学物质编号	329830997
NACRES	NA.24

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	EDQM
application(s)	pharmaceutical (small molecule)
格式	neat
储存温度	2-8℃
SMILES string	CCC1=C(C)CN(C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)N[C@H]3CC[C@H](C)CC3)C1=O
InChI	1S/C24H34N4O5S/c1-4-21-17(3)15-28(22(21)29)24(31)25-14-13-18-7-11-20(12-8-18)34(32,33)27-23(30)26-19-9-5-16(2)6-10-19/h7-8,11-12,16,19H,4-6,9-10,13-15H2,1-3H3,(H,25,31)(H2,26,27,30)/t16-,19-
InChI key	WIGIZIANZCJQQY-RUCARUNLSA-N
Gene Information	human ... ABCC8(6833), KCNJ11(3767)

安全信息

象形图
警示用语：	Warning
危险声明	H361
预防措施声明	P201 - P202 - P280 - P308 + P313 - P405 - P501
危险分类	Repr. 2
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

G2295

Sigma-Aldrich

Glimepiride

≥98% (HPLC), solid

2297.06元/50 MG; 7274.69元/250 MG;

咨询

产品说明

一般描述

格列美脲属于生物制药II类二代磺酰脲类药物。

应用

格列美脲已被用于：

作为一种降糖药物用于测试其在人脐静脉细胞(HUVEC)中的抗糖尿病功能
在乳腺癌MDA-MB-231细胞中作为磺酰脲类ATP敏感型钾通道(K_ATP)抑制剂
在新生儿胰岛样细胞簇(NICC)的葡萄糖刺激胰岛素分泌(GSIS)测定中检测其对胰岛素分泌的影响

格列美脲目前用于治疗 2 型糖尿病。

包装

50, 250 mg in glass bottle

生化/生理作用

格列美脲是一种有效的心肌梗死 K_ATP 通道阻断剂，被吡那地尔激活，IC₅₀ 值为 6.8 nM。
格列美脲可通过刺激胰腺β细胞分泌胰岛素激素来降低血糖水平。它可与与β细胞相关的一种65-kD蛋白发生相互作用。

特点和优势

该化合物由Sanofi Aventis开发。要浏览其他药物开发化合物和批准的药物/候选药物列表，单击此处。

基本信息

经验(实验)分子式	C₂₄H₃₄N₄O₅S
分子量	490.62
MDL编号	MFCD00878417
PubChem化学物质编号	24895093

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	solid
颜色	white
mp	212.2-214.5 ℃
溶解性	DMSO: >10 mg/mL
创始人	Sanofi Aventis
储存温度	room temp
SMILES string	CCC1=C(C)CN(C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)N[C@H]3CC[C@H](C)CC3)C1=O
InChI	1S/C24H34N4O5S/c1-4-21-17(3)15-28(22(21)29)24(31)25-14-13-18-7-11-20(12-8-18)34(32,33)27-23(30)26-19-9-5-16(2)6-10-19/h7-8,11-12,16,19H,4-6,9-10,13-15H2,1-3H3,(H,25,31)(H2,26,27,30)/t16-,19-
InChI key	WIGIZIANZCJQQY-RUCARUNLSA-N
Gene Information	human ... ABCC8(6833), KCNJ1(3758), KCNJ11(3767)

安全信息

象形图
警示用语：	Warning
危险声明	H361
预防措施声明	P201 - P202 - P280 - P308 + P313 - P405 - P501
危险分类	Repr. 2
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)

1292303

USP

Glimepiride

United States Pharmacopeia (USP) Reference Standard

5011.83元/200 MG;

咨询

产品说明

一般描述

应用

格列美脲目前用于治疗 2 型糖尿病。

生化/生理作用

格列美脲是一种有效的心肌梗死 K_ATP 通道阻断剂，被吡那地尔激活，IC₅₀ 值为 6.8 nM。

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式	C₂₄H₃₄N₄O₅S
分子量	490.62
MDL编号	MFCD00878417
PubChem化学物质编号	329749940

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	USP
application(s)	pharmaceutical (small molecule)
格式	neat
SMILES string	CCC1=C(C)CN(C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)N[C@H]3CC[C@H](C)CC3)C1=O
InChI	1S/C24H34N4O5S/c1-4-21-17(3)15-28(22(21)29)24(31)25-14-13-18-7-11-20(12-8-18)34(32,33)27-23(30)26-19-9-5-16(2)6-10-19/h7-8,11-12,16,19H,4-6,9-10,13-15H2,1-3H3,(H,25,31)(H2,26,27,30)/t16-,19-
InChI key	WIGIZIANZCJQQY-RUCARUNLSA-N
Gene Information	human ... ABCC8(6833), KCNJ11(3767)

安全信息

象形图
警示用语：	Warning
危险声明	H361
预防措施声明	P201 - P202 - P280 - P308 + P313 - P405 - P501
危险分类	Repr. 2
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

BP1144

Glimepiride

British Pharmacopoeia (BP) Reference Standard

382.26元/100 MG;

咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

格列美脲目前用于治疗 2 型糖尿病。

生化/生理作用

格列美脲是一种有效的心肌梗死 K_ATP 通道阻断剂，被吡那地尔激活，IC₅₀ 值为 6.8 nM。

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式	C₂₄H₃₄N₄O₅S
分子量	490.62
MDL编号	MFCD00878417
NACRES	NA.24

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	BP
格式	neat
储存温度	2-8℃
SMILES string	CCC1=C(C)CN(C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)N[C@H]3CC[C@H](C)CC3)C1=O
InChI	1S/C24H34N4O5S/c1-4-21-17(3)15-28(22(21)29)24(31)25-14-13-18-7-11-20(12-8-18)34(32,33)27-23(30)26-19-9-5-16(2)6-10-19/h7-8,11-12,16,19H,4-6,9-10,13-15H2,1-3H3,(H,25,31)(H2,26,27,30)/t16-,19-
InChI key	WIGIZIANZCJQQY-RUCARUNLSA-N
Gene Information	human ... ABCC8(6833), KCNJ11(3767)

安全信息

象形图
警示用语：	Warning
危险声明	H361
预防措施声明	P201 - P202 - P280 - P308 + P313 - P405 - P501
危险分类	Repr. 2
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

BP1141

Glimepiride for system suitability

British Pharmacopoeia (BP) Reference Standard

2978.17元/25 MG;

咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

格列美脲目前用于治疗 2 型糖尿病。

生化/生理作用

格列美脲是一种有效的心肌梗死 K_ATP 通道阻断剂，被吡那地尔激活，IC₅₀ 值为 6.8 nM。

包装

Unit quantity: 25 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式	C₂₄H₃₄N₄O₅S
分子量	490.62
MDL编号	MFCD00878417

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	BP
格式	neat
储存温度	2-8℃
SMILES string	CCC1=C(C)CN(C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)N[C@H]3CC[C@H](C)CC3)C1=O
InChI	1S/C24H34N4O5S/c1-4-21-17(3)15-28(22(21)29)24(31)25-14-13-18-7-11-20(12-8-18)34(32,33)27-23(30)26-19-9-5-16(2)6-10-19/h7-8,11-12,16,19H,4-6,9-10,13-15H2,1-3H3,(H,25,31)(H2,26,27,30)/t16-,19-
InChI key	WIGIZIANZCJQQY-RUCARUNLSA-N
Gene Information	human ... ABCC8(6833), KCNJ11(3767)

安全信息

象形图
警示用语：	Warning
危险声明	H361
预防措施声明	P201 - P202 - P280 - P308 + P313 - P405 - P501
危险分类	Repr. 2
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

036559

Fluorochem

Glimepiride

97%

1474元/1g; 3278元/5g;

咨询

基本信息

CAS Number	93479-97-1
MDL Number	MFCD00878417
Melting Point	204℃

安全信息

图形或危害标志
危险性说明	H302: Harmful if swallowed. H315: Causes skin irritation. H319: Causes serious eye irritation. H332: Harmful if inhaled. H335: May cause respiratory irritation. H361: Suspected of damaging fertility or the unborn child ..
防范说明	P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing . P264: Wash hands thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P271: Use only outdoors or in a well-ventilated area. P280: Wear . P281: Use personal protective equipment as required. P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.. P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308 + P313: IF exposed or concerned: Get medical advice/ attention. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see relevant procedures. on this label). P330: Rinse mouth. P332 + P313: If skin irritation occurs: Get medical advice/ attention. P337 + P313: If eye irritation persists: Get medical advice/attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362: Take off contaminated clothing and wash before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to in accordance with local regulation .