CAS 932986-18-0; azoramide

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产品名称

规格

包装、参考价格

A796320

MACKLIN

N-(2-(2-(4-氯苯基)噻唑-4-基)乙基)丁酰胺

10mM in DMSO

277元/1ml;

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储存：-20°C

A846880

MACKLIN

N-(2-(2-(4-氯苯基)噻唑-4-基)乙基)丁酰胺

98%

268元/25mg; 785元/100mg; 1692元/250mg; 5074元/1g;

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储存：2-8°C
状态：白色到米黄色固体

SML1560

Sigma-Aldrich

Azoramide

≥98% (HPLC)

973.81元/10 MG; 3943.82元/50 MG;

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产品说明

包装

10, 50 mg in glass bottle

生化/生理作用

Azoramide is a modulator of the unfolded protein response with antidiabetic activity. It has dual activity: Azoramide improves endoplasmic reticulum (ER) protein-folding ability and stimulates the expression of ER chaperones that protect cells against ER stress. Azoramide was shown to protect cells from death and dysfunction in multiple models of ER stress. It showed antidiabetic activity in two independent mouse models of obesity by improving insulin sensitivity and protecting pancreatic β cell function against ER stress.

基本信息

经验(实验)分子式	C₁₅H₁₇ClN₂OS
分子量	308.83
MDL编号	MFCD08009374
PubChem化学物质编号	329825964

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 30 mg/mL, clear
储存温度	2-8℃
SMILES string	ClC1=CC=C(C2=NC(CCNC(CCC)=O)=CS2)C=C1
InChI	1S/C15H17ClN2OS/c1-2-3-14(19)17-9-8-13-10-20-15(18-13)11-4-6-12(16)7-5-11/h4-7,10H,2-3,8-9H2,1H3,(H,17,19)
InChI key	VYBFWKKCWTXCQX-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

307025

Fluorochem

N-(2-(2-(4-Chlorophenyl)thiazol-4-yl)ethyl)butyramide

95%

3916元/250mg; 9856元/1g;

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基本信息

CAS Number	932986-18-0
MDL Number	MFCD08009374

安全信息

图形或危害标志
危险性说明	H302: Harmful if swallowed. H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation.
防范说明	P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing . P264: Wash hands thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P271: Use only outdoors or in a well-ventilated area. P280: Wear . P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.. P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see relevant procedures. on this label). P330: Rinse mouth. P332 + P313: If skin irritation occurs: Get medical advice/ attention. P337 + P313: If eye irritation persists: Get medical advice/attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362: Take off contaminated clothing and wash before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to in accordance with local regulation .