基本信息

技术规格

物性(参考值)

安全信息

图形或危害标志
信号词	警告
危险性说明	H315 : 造成皮肤刺激。 H319 : 造成严重眼刺激。
防范说明	P264 : 作业后彻底清洗皮肤。 P280 : 戴防护手套/戴防护眼罩/戴防护面具。 P302 + P352 : 如皮肤沾染：用水充分清洗。 P337 + P313 : 如仍觉眼刺激：求医/就诊。 P305 + P351 + P338 : 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P362+P364 : 脱掉沾污的衣服，清洗后方可重新使用。 P332 + P313 : 如发生皮肤刺激：求医/就诊。

相关法规

基本信息

安全信息

图形或危害标志
提示语	Warning
危险说明	H315 H319 H335
防范说明	P261 P305+P351+P338
WGK	3
RTECS	QT1925000
TSCA	是

应用
Used as a rubefacient, topical vasodilator used to test the efficacy of skin protection compounds (i.e. products designed to provide barriers to chemical warfare agents) and used as a flavoring agent. It is a useful synthetic intermediate. It can be used to prepare biarylcarboxamide inhibitors of phosphodiesterase IV and tumor necrosis factor-α in treatment of rheumatoid arthritis.

备注
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

基本信息

MDL
MFCD00006388

EINECS
202-261-8

分子式
C₇H₇NO₂

分子量
137.14

熔点
40-44°

沸点
208-210°

闪点
95°(203°F)

灵敏度
Ambient temperatures.

形态
Crystalline powder

溶解性
Soluble in water at 20°C 48 g/L. Soluble in alcohol, chloroform and ethyl acetate. Solubility in methanol (almost transparency).

Beilstein
113951

Merck
14,6100

GHS危害和防范说明

GHS符号

Hazard Statements
H319-H317
Causes serious eye irritation.May cause an allergic skin reaction.

Precautionary Statements
P262-P280g-P305+P351+P338
Do not get in eyes, on skin, or on clothing.Wear protective gloves.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

安全信息

危险类别
36-43
Irritating to eyes.May cause sensitization by skin contact.

安全等级
24-26-37
Avoid contact with skin.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

RTECS
QT1925000

TSCA
是

基本信息

Ref#
12721

MDL
6388

分子式
C7 H7 N O2

分子量
137.14

闪点
95

形态
White to pale yellow cryst powder

产品说明

一般描述

烟酸甲酯可用作擦剂，缓解肌肉、肌腱和关节疼痛。它也可用作食品增味剂。

应用

烟酸甲酯可用作合成二吡啶基酮配体的前体。

• 二吡啶基甲配体用于制备配位聚合物链衍生化所需的银(I)络合物，
• 5-芳基烟酸酯 ，±-sesbanine 和 1,4-二氢吡啶衍生物。

包装

5 g in glass bottle
100, 500 g in poly bottle

基本信息

产品性质

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335
预防措施声明	P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves

产品说明

一般描述

Methyl nicotinate is a volatile product of certain fruits such as carambola, soursop, wild strawberries, etc. It is used for a variety of applications in food products, cosmetics, and medicinal products.

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Methyl nicotinate may be used as a test compound to study the percutaneous penetration of methyl nicotinate through human skin in vitro and in vivo using micro-dialysis technique and different analytical techniques.
Methyl nicotinate may be used as an analytical reference standard for the determination of the analyte in biological samples, cosmetics, and pharmaceuticals by various chromatography techniques.

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

基本信息

产品性质

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335
预防措施声明	P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3

产品说明

一般描述

Methyl nicotinate (MN) is a methyl ester of nicotinic acid (NA). It is an urticant which is capable of transdermal penetration to produce vasodilation through the production of prostaglandin D2 (PGD2).

应用

Methyl nicotinate (MN) may be used as an internal standard for the high performance chromatography (HPLC) determination of 6-methylcoumarin and 3-pyridine methanol in toiletries and gas chromatographic-mass spectrometric quantification of nicotine in Hookah (water pipe) tobacco products.

包装

1 kg in poly bottle
5 kg in poly drum

基本信息

产品性质

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335
预防措施声明	P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves

产品说明

分析说明

Assay (GC, area%): ≥ 99.0 % (a/a)
Melting range (lower value): ≥ 39 °C
Melting range (upper value): ≤ 42 °C
Identity (IR): passes test
Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt.

基本信息

产品性质

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335
预防措施声明	P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3

产品说明

一般描述

Methyl nicotinate (or nicotinic acid methyl ester) is used as a rubefacient for the relief of pains in muscles, tendons, and joints. It is also used in food as a flavoring agent.

应用

Methyl nicotinate can be used as a precursor:

• In the asymmetric synthesis of 1-azasugars (glycosidase inhibitors) for biomedical applications.
• In the total synthesis of ±-sesbanine.

基本信息

产品性质

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335
预防措施声明	P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves

产品说明

一般描述

Methyl nicotinate is a potent vasodilatory drug capable of transdermal penetration. It is known to elicit distinctive erythema through the production of prostaglandin D2(PGD2) and beneficial for the treatment of respiratory, vascular and rheumatoid disorders.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 25 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

产品性质

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335
预防措施声明	P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Methyl Nicotinate is a volatile product of certain fruits such as carambola, soursop, wild strawberries, etc. It is used for a variety of applications in food products, cosmetics, and medicinal products.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA8819 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

产品性质

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335
预防措施声明	P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3

基本信息

安全信息

图形或危害标志
危险性说明	H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation.
防范说明	P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing . P264: Wash hands thoroughly after handling. P271: Use only outdoors or in a well-ventilated area. P280: Wear . P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.. P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see relevant procedures. on this label). P332 + P313: If skin irritation occurs: Get medical advice/ attention. P337 + P313: If eye irritation persists: Get medical advice/attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362: Take off contaminated clothing and wash before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to in accordance with local regulation .