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CAS: 91-19-0
分子式: C8H6N2
分子量: 130.15
沸点: 220-223℃
熔点: 29-34℃
中文名称: 
苯并吡嗪
喹诺西林
英文名称: 
1,4-Benxodiazine
Benzo[]pyrazine
1,4-benzodiazine
1,4-diazanaphthalene
benzo(a)pyrazine
benzoparadiazine
phenopiazine
phenpiazine
quinazine
quinoxaline
usaf ek-7094
Chinosalin-(i,4)
展开更多英文名
性质描述: 白色结晶。熔点28℃(29-30℃),沸点229℃,140℃(5.33kPa),108-110℃(1.6kPa),相对密度1.1334(40/4℃),折光率1.6231(40℃)。易溶于水、醇、醚、苯。该品的一水合物熔点37℃。
生产方法: 由邻苯二胺与乙二醛经环合而得。在反应锅中加水,投入亚硫酸氢钠,搅拌,慢慢加入乙二醛,温度上升到75-80℃,析出白色结晶。继续搅拌10min,再加水及邻苯二胺,于75-80℃保温1h。冷却至50℃,用碳酸钠中和至pH=8,加热至60℃,静置后分去水层,即得含量80%的苯并吡嗪,收率90%。
用途: 用作抗结核药物吡嗪酰胺的中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
Q0020TCIQuinoxaline>99.0%(GC)495元/25G;   展开

基本信息

纯度/分析方法>99.0%(GC)
分子式/分子量C8H6N2 = 130.15
外观与形状(20℃)固体
储存在惰性气体下存放于惰性气体之中
应避免的情况空气
Reaxys-RN109351
PubChem物质ID87575557
SDBS (AIST Spectral DB)716
Merck Index (14)8078
MDL编号MFCD00006719

技术规格

AppearanceWhite or Colorless to Light orange to Yellow powder to lump to clear liquid
Purity(GC)min. 99.0 %
Purity(Nonaqueous Titration)min. 98.0 %

物性(参考值)

熔点32 ℃
沸点226 ℃

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。

相关法规

RTECS#VD1225000
421356J&KQuinoxaline98%153元/25G;   309元/100G;   1235元/500G;   展开

基本信息

分子式C8H6N2
分子量130.15
熔点29-32
沸点220-223
闪点98
密度1.124
MDL编码MFCD00006719
Beilstein109351
EINECS 编号202-047-4

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
防范说明P261
P305+P351+P338
WGK3
RTECSVD1225000
A14055Alfa AesarQuinoxaline98+%452元/25g;   754元/100g;   3275元/500g;   17056元/2500g;   展开

应用
Used as dyes, pharmaceuticals and antibiotics intermediate

基本信息

MDL
MFCD00006719

EINECS
202-047-4

分子式
C8H6N2

分子量
130.15

熔点
27-32°

沸点
220-223°

闪点
98°(208°F)

密度
1.124

灵敏度
Ambient temperatures.

形态
Crystalline solid

Beilstein
109351

Merck
14,8078

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

RTECS
VD1225000

TSCA

Q1603Sigma-AldrichQuinoxaline≥98%487.6元/25 G;   展开

基本信息

经验(实验)分子式C8H6N2
分子量130.15
Beilstein109351
EC 号202-047-4
MDL编号MFCD00006719
PubChem化学物质编号24899205
NACRESNA.22

产品性质

质量水平200
测定≥98%
bp220-223 ℃ (lit.)
mp29-32 ℃ (lit.)
密度1.124 g/mL at 25 ℃ (lit.)
SMILES stringc1ccc2nccnc2c1
InChI1S/C8H6N2/c1-2-4-8-7(3-1)9-5-6-10-8/h1-6H
InChI keyXSCHRSMBECNVNS-UHFFFAOYSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
079216FluorochemQuinoxaline95%220元/1g;   308元/25g;   792元/100g;   展开

基本信息

CAS Number91-19-0
MDL NumberMFCD00006719
Boiling Point220 - 223 ℃
Melting Point29 - 32 ℃
Density1.124

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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