CAS 90365-57-4; 3h-pyrrolo(4,3,2-gh)-1,4-benzodiazonin-3-one, 1,2,4,5,6,8-hexahydro-5-(hydroxym

CAS:

90365-57-4

分子式:

C17H23N3O2

分子量:

301.38

英文名称:

3h-pyrrolo(4,3,2-gh)-1,4-benzodiazonin-3-one, 1,2,4,5,6,8-hexahydro-5-(hydroxym

(2S-(2R*,5R*))-ethyl)-1- methyl-2-(1-methylethyl)

(-)-indolactam v

indolactam v

用途:

(-)-Indolactam V is a PKC activator, with Ki of 3.36 nM, 1.03 μM for η-CRD2 (PKCη surrogate peptide), γ-CRD2 (PKCγ surrogate peptide), and Kd of 5.5 nM (η-C1B), 7.7 nM (ε-C1B), 8.3 nM (δ-C1B), 18.9 nM

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

I913017

MACKLIN

吲哚内酰胺 V

≥98%

13108元/5mg;

咨询

储存：-20°C，密闭，干燥

I0661

Sigma-Aldrich

(-)-Indolactam V

≥96% (HPLC)

3319.3元/1 MG;

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产品说明

包装

1 mg in glass bottle

生化/生理作用

(-)-Indolactam V is a PKC activator shown to effect differentiation in embryonic stem cells leading to development of pancreatic precursors. It is active in the mouse model.
(−)-Indolactam V is naturally present in Streptoverticillium blastmyceticum. It serves as a precursor to the teleocidin class which are alkaloids. It is a the pharmacophore of lyngbyatoxin and teleocidins.

特点和优势

This compound is featured on the PKC page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式	C₁₇H₂₃N₃O₂
分子量	301.38
MDL编号	MFCD00151197
PubChem化学物质编号	329815323
NACRES	NA.77

产品性质

质量水平	100
测定	≥96% (HPLC)
形式	powder
颜色	white
储存温度	−20℃
SMILES string	CC(C)[C@@H]1N(C)c2cccc3[nH]cc(C[C@@H](CO)NC1=O)c23
InChI	1S/C17H23N3O2/c1-10(2)16-17(22)19-12(9-21)7-11-8-18-13-5-4-6-14(15(11)13)20(16)3/h4-6,8,10,12,16,18,21H,7,9H2,1-3H3,(H,19,22)/t12-,16-/m0/s1
InChI key	LUZOFMGZMUZSSK-LRDDRELGSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

050739

Fluorochem

(-)-Indolactam V

>99%

4444元/1mg;

咨询

基本信息

CAS Number	90365-57-4
MDL Number	MFCD00151197