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CAS: 9033-12-9
英文名称: 
glyoxalase i grade x from yeast
用途: Glyoxalase I is universally expressed and involved in the protection against cellular damage due to cytotoxic metabolites such as advanced glycation end products (AGEs). It is an integral component of the detoxification system, catalyzing the conversion of reactive, acyclic a-oxoaldehydes into the corresponding a-hydroxyacids in a glutathione-dependent manner.
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货号品牌产品名称规格包装、参考价格详情
G920008MACKLIN乙二醛酶I≥400 units/mg protein2450元/200U;   展开
储存:2-8°C
状态:液体
G4252Sigma-AldrichGlyoxalase I from Saccharomyces cerevisiaeGrade IV, buffered aqueous glycerol solution, ≥400 units/mg protein1748.28元/200 UNITS;   3326.55元/500 UNITS;   6670.86元/1000 UNITS;   12374.5元/2500 UNITS;   展开

产品说明

一般描述

Glyoxalase detoxification system consists of glyoxalase (GLO)-I and GLO-II. GLO-I is a cytosolic, 42 kDa, dimeric Zn2+ metalloenzyme.

应用

Glyoxalase I from Saccharomyces cerevisiae has been used as a standard in Glyoxalase I assay for C. dilatata females and brooded encapsulated embryos. It has also been used as a standard for calibration curve generation for quantifying glyoxalase I from brain tissues and cerebral microvessels.

包装

500, 1000, 2500 units in glass bottle

生化/生理作用

Glyoxalase I is universally expressed and involved in the protection against cellular damage due to cytotoxic metabolites such as advanced glycation end products (AGEs). It is an integral component of the detoxification system, catalyzing the conversion of reactive, acyclic a-oxoaldehydes into the corresponding a-hydroxyacids in a glutathione-dependent manner.

单位定义

One unit will form 1.0 μmole of S-lactoylglutathione from methylglyoxal and reduced glutathione per min at pH 6.6 at 25 ℃.

外形

Solution in 50% glycerol, 0.4 M (NH4)2SO4 and 0.002 M KH2PO4 pH 6.5

分析说明

Protein determined by biuret.

基本信息

酶学委员会(EC)编号4.4.1.5 ( BRENDA | IUBMB )
MDL编号MFCD00131225
NACRESNA.54

产品性质

质量水平200
类型Grade IV
形式buffered aqueous glycerol solution
specific activity≥400 units/mg protein
异质活性glyoxalase II ≤1%
储存温度2-8℃

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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