| CAS: | 9032-88-6 | |
| 英文名称: |
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| 用途: | Fumarase (Fumarate hydratase) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid (TCA), or Krebs cycle. This enzyme exists in both a cytosolic form and an N-terminal extended mitochondrial form. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension is the same form as in the cytoplasm. Fumarase deficiency can lead to progressive encephalopathy, cerebral atrophy and developmental delay and this enzyme also is thought to act as a tumor suppressor. |
| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | |||||||||||||||||||||||||||||||||||||||
| F920203 | MACKLIN | 延胡索酸酶 | ≥95% (SDS-PAGE) | 8384元/100μg; | 咨询 | ||||||||||||||||||||||||||||||||||||||
储存：−20°C 状态：冻干 | |||||||||||||||||||||||||||||||||||||||||||
| F1757 | Sigma-Aldrich | Fumarase from porcine heart | ammonium sulfate suspension, ≥300 units/mg protein (biuret) | 6367.06元/500 units; 25411.2元/2500 units; 40432.1元/5000 units; | 咨询 | ||||||||||||||||||||||||||||||||||||||
产品说明 一般描述 Fumarase (FH in human) is a well-known tricarboxylic-acid-cycle enzyme found in both the cytoplasm and mitochondria of all eukaryotes. 应用 Fumarase from porcine heart has been used:
Fumarase is used as a protein calibration standard in the purification of intact DNA polymerase a/primase from mouse cells. 生化/生理作用 Fumarase catalyzes the reversible hydration of fumarate to malate. In its mitochondrial form, fumarate is involved in the Krebs Cycle, while the cytosolic form is involved in amino acid metabolism. 单位定义 One unit will convert 1.0 μmole of 外形 Suspension in 3.2 M (NH4)2SO4, 0.05 M KH2PO4, pH 7.5, 0.014 M 2-mercaptoethanol 制备说明 Isolated by the method of Beeckmans, S., and Kanarek, L., Eur. J. Biochem., 78, 437 (1977). Affinity purified. 基本信息
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| SRP6120 | Sigma-Aldrich | Fumarase human | recombinant, expressed in E. coli, ≥95% (SDS-PAGE) | 5165.48元/100 μG; | 咨询 | ||||||||||||||||||||||||||||||||||||||
产品说明 一般描述 Fumarase (Fumarate hydratase) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid (TCA), or Krebs cycle. This enzyme exists in both a cytosolic form and an N-terminal extended mitochondrial form. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension is the same form as in the cytoplasm. Fumarase deficiency can lead to progressive encephalopathy, cerebral atrophy and developmental delay and this enzyme also is thought to act as a tumor suppressor. 外形 1 mg/mL solution in 20 mM Tris-HCl buffer (pH 8.0). 制备说明 Centrifuge the vial prior to opening. 其他说明 MASQNSFRIE YDTFGELKVP NDKYYGAQTV RSTMNFKIGG VTERMPTPVI KAFGILKRAA AEVNQDYGLD PKIANAIMKA ADEVAEGKLN DHFPLVVWQT GSGTQTNMNV NEVISNRAIE MLGGELGSKI PVHPNDHVNK SQSSNDTFPT AMHIAAAIEV HEVLLPGLQK LHDALDAKSK EFAQIIKIGR THTQDAVPLT LGQEFSGYVQ QVKYAMTRIK AAMPRIYELA AGGTAVGTGL NTRIGFAEKV AAKVAALTGL PFVTAPNKFE ALAAHDALVE LSGAMNTTAC SLMKIANDIR FLGSGPRSGL GELILPENEP GSSIMPGKVN PTQCEAMTMV AAQVMGNHVA VTVGGSNGHF ELNVFKPMMI KNVLHSARLL GDASVSFTEN CVVGIQANTE RINKLMNESL MLVTALNPHI GYDKAAKIAK TAHKNGSTLK ETAIELGYLT AEQFDEWVKP KDMLGPK 基本信息
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安全信息
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