| CAS: | 9030-23-3 | |
| 英文名称: |
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| 用途: | An enzyme that catalyzes the reversible conversion of thymidine to thymine. Thymidine phosphorylase is part of the pyrimidine nucleoside salvage pathway. This pathway allows pyrimidine bases to be recycled for nucleotide biosynthesis, while the pentose 1-phosphates are converted to intermediates of the pentose phosphate shunt and glycolysis. The E. coli thymidine phosphorylase shares 40% sequence homology with the human sequence, which has been found to be identical to the angiogenic agent platelet-derived endothelial growth factor. The purified E. coli enzyme has been shown to stimulate blood vessel growth in chick chorioallantoic membrane assays. |
| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 | ||||||||||||||||||||||||||||||||||
| T919798 | MACKLIN | 胸苷磷酸化酶 | recombinant, expressed in E. coli, buffered aqueous solution, ≥500 units/mL | 2240元/500U; | 展开 | ||||||||||||||||||||||||||||||||||
储存：2-8°C 状态：无色到黄色液体 | |||||||||||||||||||||||||||||||||||||||
| T2807 | Sigma-Aldrich | Thymidine Phosphorylase, recombinant from Escherichia coli | recombinant, expressed in E. coli, buffered aqueous solution, ≥500 units/mL | 1683.5元/500 UNITS; 2294.74元/1000 UNITS; 7865.05元/5000 UNITS; | 展开 | ||||||||||||||||||||||||||||||||||
产品说明 一般描述 Thymidine phosphorylase inhibits vascular smooth muscle cell proliferation. 应用 Thymidine phosphorylase has been used in a study to assess TAS-102 treatment in patients with advanced solid tumors. Thymidine phosphorylase has also been used in a study to investigate antitumor effects of the FP3 protein on patient-derived tumor tissue xenograft models of primary colon carcinoma. 包装 5000 units in glass bottle 生化/生理作用 An enzyme that catalyzes the reversible conversion of thymidine to thymine. Thymidine phosphorylase is part of the pyrimidine nucleoside salvage pathway. This pathway allows pyrimidine bases to be recycled for nucleotide biosynthesis, while the pentose 1-phosphates are converted to intermediates of the pentose phosphate shunt and glycolysis. The E. coli thymidine phosphorylase shares 40% sequence homology with the human sequence, which has been found to be identical to the angiogenic agent platelet-derived endothelial growth factor. The purified E. coli enzyme has been shown to stimulate blood vessel growth in chick chorioallantoic membrane assays. 单位定义 One unit will convert 1.0 μmole each of thymidine and phosphate to thymine and 2-deoxyribose 1-phosphate per min at pH 7.4 at 25℃. 外形 Solution in 0.5 M potassium phosphate containing 2 mM uracil, 0.02% sodium azide and bovine serum albumin 制备说明 Cloned from E. coli and produced in overexpressing E. coli 基本信息
产品性质
安全信息
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| SRE0006 | Sigma-Aldrich | Thymidine Phosphorylase, recombinant from Escherichia coli | recombinant, expressed in E. coli, Suitable for manufacturing of diagnostic kits and reagents, buffered aqueous solution, ≥500 units/mL | 8657.81元/5000 UNITS; | 展开 | ||||||||||||||||||||||||||||||||||
产品说明 包装 5000 units in glass bottle 生化/生理作用 An enzyme that catalyzes the reversible conversion of thymidine to thymine. Thymidine phosphorylase is part of the pyrimidine nucleoside salvage pathway. This pathway allows pyrimidine bases to be recycled for nucleotide biosynthesis, while the pentose 1-phosphates are converted to intermediates of the pentose phosphate shunt and glycolysis. The E. coli thymidine phosphorylase shares 40% sequence homology with the human sequence, which has been found to be identical to the angiogenic agent platelet-derived endothelial growth factor. The purified E. coli enzyme has been shown to stimulate blood vessel growth in chick chorioallantoic membrane assays. 单位定义 One unit will convert 1.0 μmole each of thymidine and phosphate to thymine and 2-deoxyribose 1-phosphate per min at pH 7.4 at 25℃. 制备说明 Cloned from E. coli and produced in overexpressing E. coli 基本信息
产品性质
安全信息
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| T6632 | Sigma-Aldrich | Thymidine Phosphorylase, recombinant from Escherichia coli | recombinant, expressed in E. coli, buffered aqueous solution, ≥900 units/mL, 0.2 μm filtered | 18074.4元/5000 UNITS; | 展开 | ||||||||||||||||||||||||||||||||||
产品说明 一般描述 Thymidine phosphorylase inhibits vascular smooth muscle cell proliferation. 应用 Thymidine phosphorylase has been used in a study to evaluate biomarkers for advanced breast cancer patients treated with capecitabine-based first-line chemotherapy. Thymidine phosphorylase has also been used in a study to investigate implications for the clinical efficacy of nucleoside analogues. 生化/生理作用 An enzyme that catalyzes the reversible conversion of thymidine to thymine. Thymidine phosphorylase is part of the pyrimidine nucleoside salvage pathway. This pathway allows pyrimidine bases to be recycled for nucleotide biosynthesis, while the pentose 1-phosphates are converted to intermediates of the pentose phosphate shunt and glycolysis. The E. coli thymidine phosphorylase shares 40% sequence homology with the human sequence, which has been found to be identical to the angiogenic agent platelet-derived endothelial growth factor. The purified E. coli enzyme has been shown to stimulate blood vessel growth in chick chorioallantoic membrane assays. 单位定义 One unit will convert 1.0 μmole each of thymidine and phosphate to thymine and 2-deoxyribose 1-phosphate per min at pH 7.4 at 25℃. 外形 Solution in 0.5 M potassium phosphate containing 2 mM uracil, 0.02% sodium azide and bovine serum albumin 制备说明 Cloned from E. coli and produced in overexpressing E. coli 基本信息
产品性质
安全信息
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