| CAS: | 9028-48-2 | |
| 英文名称: |
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| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 | ||||||||||||||||||||||||||||||||
| I922772 | MACKLIN | 异柠檬脱氢酶 (NADP) 来源于猪心脏 | 3-20 units/mg protein | 621元/10mg; 1548元/25mg; 4704元/100mg; | 展开 | ||||||||||||||||||||||||||||||||
储存：2-8°C 状态：液体 | |||||||||||||||||||||||||||||||||||||
| I2002 | Sigma-Aldrich | Isocitric Dehydrogenase (NADP) from porcine heart | Type IV, buffered aqueous glycerol solution, 3-20 units/mg protein | 1343.37元/25 MG; 4006.58元/100 MG; 8745.42元/250 MG; 15361元/500 MG; | 展开 | ||||||||||||||||||||||||||||||||
产品说明 单位定义 在37℃条件下，当pH为7.4时，一个单位每分钟将1.0 μ摩尔的异柠檬酸盐转化为至α-酮戊二酸。 外形 50%甘油EDTA缓冲盐溶液，pH 6.0 基本信息
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| I1877 | Sigma-Aldrich | Isocitric Dehydrogenase (NADP) from porcine heart | Type I, 0.5-3.0 unit/mg solid (plus numerous enzyme activities associated with porcine heart) | 2487.22元/500 MG; 4329.21元/1 G; | 展开 | ||||||||||||||||||||||||||||||||
产品说明 包装 500 mg in poly bottle 生化/生理作用 Isocitrate dehydrogenase (IDH) plays a major role in the Krebs cycle by catalyzing the oxidative decarboxylation of isocitrate. The oxidative decarboxylation of isocitrate generates α-ketoglutarate and NADPH. NADPH produced is essential for the production of fatty acids and cholesterol. This NADP-dependent molecules serves as homodimers. 质量 粗品 单位定义 One unit will convert 1.0 μmole of isocitrate to α-ketoglutarate per min at pH 7.4 at 37℃. 基本信息
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| I5036 | Sigma-Aldrich | Isocitrate Dehydrogenase 1 (NADP+) human | recombinant, expressed in E. coli, lyophilized powder, ≥80 units/mg protein | 5957元/100 μG; | 展开 | ||||||||||||||||||||||||||||||||
产品说明 一般描述 Isocitrate dehydrogenase 1 (IDH1) gene is located on human chromosome 2q33. IDH1 is present in the cytoplasm and peroxisomes. It is expressed at high levels in the mammalian liver. IDH1 consists of a C-terminal tripeptide peroxisome, that targets the signal one sequence. 生化/生理作用 Isocitrate dehydrogenase 1 (IDH1) help in the oxidative carboxylation of isocitrate to α-ketoglutarate, that results in the formation of reduced nicotinamide adenine dinucleotide phosphate (NADPH). It participates in lipid metabolism and glucose sensing. Suppressing IDH1 in pancreatic islets affects the insulin secretion, induced by glucose and leads to increase in lactate production. 单位定义 One unit corresponds to the amount of enzyme which converts 1.0 μmol DL-isocitrate to α-ketoglutarate per minute at pH 7.4 and 37 ℃ (NADP as cofactor). 外形 Supplied as a lyophilized powder containing Tris-HCl pH 8.0, trehalose, ammonium sulfate and DTT 基本信息
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| I2411 | Sigma-Aldrich | Isocitrate Dehydrogenase 1 (NADP+) human | recombinant, expressed in Sf9 cells, ≥90% (SDS-PAGE) | 8280.91元/10 μG; | 展开 | ||||||||||||||||||||||||||||||||
产品说明 一般描述 Human Isocitrate Dehydrogenase (IDH1), also known as oxalosuccinate decarboxylase, full length [amino acids 1-414 (end)] with C-terminal FLAG-tag, expressed in Sf9 cells via a baculovirus expression system. 应用 Human Isocitrate Dehydrogenase (IDH1) is useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. It may be useful as a biomarker for diagnosis and prognosis prediction of non-small cell lung cancer . 生化/生理作用 Human Isocitrate Dehydrogenase (IDH1), also known as oxalosuccinate decarboxylase, is a full length amino acid with a C-terminal FLAG-tag and is expressed in Sf9 cells via a baculovirus expression system. IDH1 expression has been correlated with poor survival of non-small cell lung cancer. IDH1 promotes tumor growth . 外形 Solution in 45 mM Tris-HCl, 124 mM NaCl, 2.4 mM KCl, 90 μg/ml FLAG peptide, 3 mM DTT, and 10% glycerol at pH 8.0. 基本信息
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