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CAS: 90098-04-7
分子式: C19H15ClN2O4
分子量: 370.79
熔点: 290 °C(dec.)(lit.)
中文名称: 
瑞巴匹特
α-[(4-氯苯甲酰基)氨基]-1,2-二氢-2-氧代-4-喹啉丙酸
英文名称: 
Rebamipid
-[(4-Chlorobenzoyl)amino]-1,2-dihydro-2-oxo-4-quinolinepropanoic acid
1,2-dihydro-alpha-((4-chlorobenzoyl)amino)-2-oxo-4-quinolinepropanoic aci (
(+-)-1,2-dihydro-alpha-((4-chlorobenzoyl)amino)-2-oxo-4-quinolinepropano ic a
(+-)-2-(4-chlorobenzoylamino)-3-(2(1h)-quinolinon-4-yl)propionic acid
opc 12759
opc-12759
2-dihydro-alpha-((4-chlorobenzoyl)amino)-2-oxo- (+-)-4-quinolinepropanoic aci
用途: 新型抗溃疡药。
推荐供应商
货号品牌产品名称规格包装、参考价格
R861109MACKLIN瑞巴派特≥98%36元/1g;   63元/5g;   258元/25g;   962元/100g;   咨询
储存:室温,干燥
状态:白色粉末
R793752MACKLIN瑞巴派特10mM in DMSO126元/1ml;   咨询
储存:-20°C
状态:白色粉末
R0085TCIRebamipide>98.0%(HPLC)160元/1G;   390元/5G;   1250元/25G;   咨询

基本信息

纯度/分析方法>98.0%(HPLC)
分子式/分子量C19H15ClN2O4 = 370.79
外观与形状(20℃)固体
Reaxys-RN5384689
PubChem物质ID125307349
Merck Index (14)8124
MDL编号MFCD11114396

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Neutralization titration)min. 95.0 %

物性(参考值)

熔点290 ℃(dec.)

相关法规

RTECS#VC2518500
268433J&KRebamipide99%, 内源性前列腺素诱导剂, 同时是自由基清除剂129元/5MG;   340元/25MG;   咨询

基本信息

分子式C19H15ClN2O4
分子量370.79
熔点290
MDL编码MFCD00866895
Beilstein5384689
Merck14,8124
存储条件Freezer -20℃

安全信息

图形或危害标志
提示语Warning
危险说明H302
H400
H410
防范说明P264
P270
P273
P301+P312
P330
P391
P501
UN号码3077
危险分类9
包装等级III
WGK3
RTECSVC2518500
R5655Sigma-AldrichRebamipide hydrate≥98% (HPLC), powder970.11元/5 MG;   3099.54元/25 MG;   咨询

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

Rebamipide is an anti-ulcer agent with free-radical scavenging and anti-inflammatory effects. It has been used for mucosal protection, healing of gastroduodenal ulcers, and treatment of gastritis. It works by enhancing mucosal defense, scavenging free radicals, and temporarily activating COX-2 genes. Rebamipide significantly reduced ulcerogenesis and maintained mucosal superoxide dismutase (SOD) activity. It has also been used for the treatment of Behçet′s disease. Rebamipide may be involved in a noval mechanism to enhance tear secretion and increase mucin levels covering conjunctiva and cornea.
Rebamipide helps to reduce intestinal injury, stimulated by radiation.

基本信息

经验(实验)分子式C19H15ClN2O4 · xH2O
分子量370.79 (anhydrous basis)
MDL编号MFCD11114396
PubChem化学物质编号329824033
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white
溶解性DMSO: >5 mg/mL
SMILES stringO.OC(=O)C(CC1=CC(=O)Nc2ccccc12)NC(=O)c3ccc(Cl)cc3
InChI1S/C19H15ClN2O4.H2O/c20-13-7-5-11(6-8-13)18(24)22-16(19(25)26)9-12-10-17(23)21-15-4-2-1-3-14(12)15;/h1-8,10,16H,9H2,(H,21,23)(H,22,24)(H,25,26);1H2
InChI keyWQRHVBKNEDPECA-UHFFFAOYSA-N

安全信息

象形图GHS06
警示用语:Danger
危险声明H301
预防措施声明P301 + P310
危险分类Acute Tox. 3 Oral
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Faceshields, Gloves, type N95 (US)
300998Fluorochem2-(4-CHLOROBENZOYLAMINO)-3-(1,2-DIHYDRO-2-OXO-4-QUINOLYL)PROPIONIC ACID95%990元/1g;   2662元/5g;   8514元/25g;   咨询

基本信息

CAS Number90098-04-7
MDL NumberMFCD00866895
CAS号首数字顺序排列: 1 2 3 4 5 6 7 8 9