产品说明

一般描述

Kallikrein exists as an inactive prokallikrein in the porcine pancreas. The porcine kallikrein gene region is localized on chromosome 6q12-q21.

应用

Kallikrein from porcine pancreas has been used:

• as a matrix metalloproteinase-9 (MMP-9) zymogen activator
• as a component of cell culture to test its effect on rat subventricular zone (SVZ) cells and oligodendrocyte progenitor cells (OPC) proliferation and survival
• as a model enzyme to track kinetic data and visual detection limits of hydrolysis by hydrolytic enzymes in the two-phases array

包装

250, 1000 units in poly bottle

生化/生理作用

Kallikrein active forms are generated by the enzymatic action of trypsin. It is a serine protease that mediates the activation of growth factors and substrates.

单位定义

One unit will hydrolyze 1.0 μmole of Nα-benzoyl-L-arginine ethyl ester (BAEE) to Nα-benzoyl-L-arginine and ethanol per min at pH 8.7 at 25℃.

基本信息

产品性质

安全信息

产品说明

单位定义

一个酶活性单位是指在pH 8.7、25℃条件下，每分钟将1.0 μMN_α-苯甲酰基-L-精氨酸乙酯(BAEE)水解为N_α-苯甲酰基-L-精氨酸和乙醇所需的酶量。

外形

溶于20 mM Tris-HCl (pH 7.8)和100 mM NaCl的溶液中。

基本信息

产品性质

安全信息