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关键词:       仅模糊查询
CAS: 9000-89-9
英文名称: 
oxidase, l-amino acid
aromatic l-amino acid oxidase
e.c. 1.4.3.2
l-amino acid oxidase
l-aminooxidase
l-amino acid oxidase from crotalus ada-manteus
oxidase,
oxidase,l-amino acid
oxidase,l-aminoacid
推荐供应商
货号品牌产品名称规格包装、参考价格详情
L864716MACKLINL-氨基酸氧化酶 来源于东部菱背响尾蛇毒液≥4 units/mg protein3387元/5mg;   展开
储存:2-8°C
状态:冻干粉末
A5147Sigma-AldrichL-Amino Acid Oxidase from Crotalus atrox (Western Diamondback Rattlesnake)Type VI, dried venom1240.93元/100 MG;   1931.68元/250 MG;   3416.24元/500 MG;   5883.51元/1 G;   展开

产品说明

应用

L-amino acid oxidase is used to convert L-amino acids to their corresponding α-keto acids. Product A5147 is from Crotalus atrox. L-amino acid oxidase, from Sigma, has been used in leucine aminopeptidase (LAP) activity assays .

生化/生理作用

L-amino acid oxidase is involved in various metabolic pathways such as alanine and aspartate metabolism, methionine metabolism, valine, leucine and isoleucine degradation, tyrosine metabolism, phenylalanine metabolism, tryptophan metabolism, phenylalanine, tyrosine and tryptophan biosynthesis, and alkaloid biosynthesis .

基本信息

酶学委员会(EC)编号1.4.3.2 ( BRENDA | IUBMB )
EC 号232-564-0
MDL编号MFCD00131454
NACRESNA.54

产品性质

质量水平200
类型Type VI
形式dried venom
储存温度−20℃

安全信息

象形图GHS06
警示用语:Danger
危险声明H300 + H310 + H330
预防措施声明P262 - P280 - P301 + P310 + P330 - P302 + P352 + P310 - P304 + P340 + P310
危险分类Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral
储存分类代码6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
A9378Sigma-AldrichL-Amino Acid Oxidase from Crotalus adamanteusType IV, ≥4.0 units/mg protein, aqueous suspension2487.22元/2 MG;   5006.97元/5 MG;   9280.95元/10 MG;   展开

产品说明

应用

L-amino acid oxidase (LAAO) is used to convert L-amino acids to their corresponding α-keto acids. L-amino acid oxidase, from Sigma, has been used in leucine aminopeptidase (LAP) activity assays. 35S dimethylsulfoniopropionate (DMSP) has been synthesized chemically from 35S L-methionine using LAAO from Sigma to form 35S 3-methiolpropionate.

包装

2, 5, 10 mg in glass bottle
Package size based on protein content

生化/生理作用

L-Amino acid oxidase is a flavoprotein with a molecular weight of 130 kDa. It consists of two different subunits of approximately 70,000 Da. Each molecule of holoenzyme has two FAD molecules. It is a glycoprotein containing about 2-5% carbohydrate, including sialic acid. Optimum pH is approximately 7.5.The enzyme may be reversibly inactivated by incubation in phosphate buffer, pH 7.5 at 38 ℃. L-amino acid oxidase is involved in various metabolic pathways such as alanine and aspartate metabolism, methionine metabolism, valine, leucine and isoleucine degradation, tyrosine metabolism, phenylalanine metabolism, tryptophan metabolism, phenylalanine, tyrosine and tryptophan biosynthesis, and alkaloid biosynthesis. It occurs in many snake venoms apart from microorganisms and animal tissue, especially in kidney and liver.

单位定义

One Unit oxidizes one micromole of L-leucine per minute at 25 ℃, pH 7.6

制备说明

Dissolves in water at 1 mg/mL concentration to form a clear solution.

基本信息

酶学委员会(EC)编号1.4.3.2 ( BRENDA | IUBMB )
EC 号232-564-0
MDL编号MFCD00131454
NACRESNA.54

产品性质

质量水平200
类型Type IV
形式aqueous suspension
specific activity≥4.0 units/mg protein
分子量 ~130 kDa
包含 toluene as preservative
浓度≥5.0 mg/mL
溶解性H2O: soluble 1.0 mg/mL, clear
储存温度2-8℃

安全信息

象形图GHS06
警示用语:Danger
危险声明H300 + H310 + H330
预防措施声明P262 - P280 - P301 + P310 + P330 - P302 + P352 + P310 - P304 + P340 + P310
危险分类Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral
储存分类代码6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
A9253Sigma-AldrichL-Amino Acid Oxidase from Crotalus adamanteusType I (dried venom)3184.66元/100 MG;   6295.68元/250 MG;   展开

产品说明

一般描述

L-氨基酸氧化酶(LAAO)是一种黄素蛋白,分子量为130 kDa。它由两个大约70 kDa的不同亚基组成。全酶的每个分子都有两个黄素腺嘌呤二核苷酸(FAD)分子。LAAO是一种糖蛋白,含有大约2-5%的碳水化合物,包括唾液酸。最适pH约为7.5。除微生物和动物组织外,它还存在于许多蛇毒液中,尤其是在肾脏中。在N-末端区域,它有一个带谷氨酸残基的βαβ结构域。LAAO使毒液呈黄色。

应用

来自响尾蛇的L-氨基酸氧化酶已被用于定量测定亚胺脱氨酶活性中的rid 蛋白质。
L-氨基酸氧化酶 (LAAO) 可用于将L-氨基酸转化为相应的α-酮酸。来自Sigma的L-氨基酸氧化酶已被用于亮氨酸氨基肽酶(LAP)活性测定。该酶为固定化酶,可用于化学发光检测酶促流动注射方法中进行L-丙氨酸的现场测定。

生化/生理作用

来自响尾蛇的L-氨基酸氧化酶(LAAO)需要Mg2 +才能激活。N末端区域对于FAD的结合是必不可少的。通过LAAO的氧化反应生成的 H2O2可防止血小板聚集,并引起水肿和细胞凋亡。乙二胺四乙酸(EDTA)和苯甲基磺酰氟(PMSF)可抑制LAAO的活性。

制备说明

溶于 1 mg/mL 浓度的水中,形成澄清溶液。

基本信息

酶学委员会(EC)编号1.4.3.2 ( BRENDA | IUBMB )
EC 号232-564-0
MDL编号MFCD00131454
NACRESNA.54

产品性质

类型Type I (dried venom)
Type I
质量水平200
分子量 ~130 kDa
溶解性H2O: soluble 1.0 mg/mL, clear(lit.)
储存温度−20℃

安全信息

象形图GHS06
警示用语:Danger
危险声明H300 + H310 + H330
预防措施声明P262 - P280 - P301 + P310 + P330 - P302 + P352 + P310 - P304 + P340 + P310
危险分类Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral
储存分类代码6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
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