| CAS: | 894804-07-0 | ||
| 分子式: | C18H20N4O4 | ||
| 分子量: | 356.38 | ||
| 英文名称: |
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| 用途: | JNK Inhibitor VIII (TCS JNK 6o) 是 c-Jun N-末端激酶 (JNK-1, -2, -3) 抑制剂，抑制 JNK-1、JNK-2、JNK-3 的 Ki 值分别为 2 nM、4 nM、52 nM，对 JNK-1、JNK-2 的 IC50 值分别是 45 nM 和160 nM。 |
| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 | ||||||||||||||||||||||||||||||||
| J797588 | MACKLIN | JNK Inhibitor VIII | 10mM in DMSO | 1304元/1ml; | 展开 | ||||||||||||||||||||||||||||||||
储存：-20°C | |||||||||||||||||||||||||||||||||||||
| J876693 | MACKLIN | JNK Inhibitor VIII | ≥99% | 255元/5mg; 660元/25mg; | 展开 | ||||||||||||||||||||||||||||||||
储存：2-8℃ | |||||||||||||||||||||||||||||||||||||
| 420135 | Sigma-Aldrich | JNK Inhibitor VIII-CAS 894804-07-0-Calbiochem | The JNK Inhibitor VIII, also referenced under CAS 894804-07-0, controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation appl | 3543.57元/5 MG; | 展开 | ||||||||||||||||||||||||||||||||
产品说明 一般描述 A cell-permeable pyridinylamide compound that acts as an ATP-competitive, reversible inhibitor of JNK (Ki = 2 nM, 4 nM and 52 nM for JNK1, 2 and 3, respectively) and displays excellent selectivity over 72 other kinases. Inhibits c-jun phosphorylation with an EC50 of 920 nM in HepG2 cells. Preferentially blocks the growth of PTEN null mouse embryonic fibroblasts. 包装 5 mg in Plastic ampoule 生化/生理作用 Cell permeable: yes 警告 Toxicity: Standard Handling (A) 其他说明 Vivanco, I., et al. 2007. Cancer Cell11, 555. 法律信息 CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany 基本信息
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