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CAS: 88-10-8
分子式: C5H10ClNO
分子量: 135.59
沸点: 121-123℃
熔点: -32-123℃
中文名称: 
N,N-二乙氨基甲酰氯
N,N-二乙基氯甲酰胺
二乙胺基甲酰氯
二乙氨基甲酰氯
N,N-二乙基甲酰氯胺
英文名称: 
N,N-Diethylaminoformyl chloride
diethyl-Carbamic chloride
N,N-Diethyl chloroformamide
diethyl-carbamoyl chlorid
diethyl-carbamic chlorid
diethyl-carbamidoyl chlorid
diethylamid kyseliny chlormravenci
diethylcarbamic chloride
diethylcarbamoyl chloride
diethylcarbamyl chloride
diethylchloroformamide
n,n-diethylcarbamoyl chloride
n,n-diethylchloroformamide
Chloroformic acid diethylamide
Carbamic chloride,diethyl-
DECF
展开更多英文名
性质描述: 浅黄色刺激性油状液体。熔点-32℃,沸点186-190℃,117-123℃(17.73kPa),相对密度1.070,折射率1.4515,闪点75℃。遇水极易分解,放出二乙胺和二氧化碳。
生产方法: 以乙二胺为原料,与光气进行甲酰氯化反应,制得粗品二乙胺基甲酰氯,经脱酸而得成品。
用途: 该品为医药、农药中间体,用于抗血丝虫药海群生、除草剂杀草丹等的生产。
推荐供应商
货号品牌产品名称规格包装、参考价格
N807161MACKLIN|N|,|N|-二乙基氯甲酰胺98%87元/25g;   270元/100g;   1135元/500g;   咨询
储存:室温,干燥
状态:无色到橙色液体
折射率:n20/D 1.451(lit.)
N742846MACKLIN|N|,|N|-二乙基氯甲酰胺Standard for GC, ≥99.8%(GC)228元/5g;   咨询
储存:室温, 干燥
状态:液体
D0482TCIDiethylcarbamoyl Chloride>98.0%(GC)(T)100元/25G;   170元/100G;   790元/500G;   咨询

基本信息

纯度/分析方法>98.0%(GC)(T)
分子式/分子量C5H10ClNO = 135.59
外观与形状(20℃)液体
储存在惰性气体下存放于惰性气体之中
应避免的情况湿气 (分解)
Reaxys-RN506687
PubChem物质ID87567153
SDBS (AIST Spectral DB)10235
MDL编号MFCD00000636

技术规格

AppearanceColorless to Light yellow to Light orange clear liquid
Purity(GC)min. 98.0 %
Purity(Argentometric Titration)min. 98.0 %

物性(参考值)

沸点195 ℃
闪点76 ℃
比重1.07
折射率1.45

安全信息

图形或危害标志
信号词警告
危险性说明H332 : 吸入有害。
H303 : 吞咽可能有害。
H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
H351 : 怀疑致癌。
H335 : 可能造成呼吸道刺激。
H227 : 可燃液体。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P261 : 避免吸入粉尘/烟/气体/烟雾/蒸气/喷雾。
P202 : 在阅读并明了所有安全措施前切勿搬动。
P210 : 远离热源/火花/明火/热表面。禁止吸烟。
P201 : 使用前取得专用说明。
P271 : 只能在室外或通风良好之处使用。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P370 + P378 : 火灾时:使用干砂、干粉或抗醇泡沫灭火。
P312 : 如感觉不适,呼叫急救中心/医生。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
P304 + P340 + P312 : 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。如感觉不适,呼叫急救中心/医生。
P403 + P233 : 存放在通风良好的地方。保持容器密闭。
P403 + P235 : 存放在通风良好的地方。保持低温。
P405 : 存放处须加锁。

相关法规

RTECS#FD4025000
A15701Alfa AesarDiethylcarbamyl chloride98%406元/25g;   1704元/100g;   8481元/500g;   咨询

应用
It is used in the production of pharma ingredients. It is a reagent in the synthesis of S-Methyl-N,N-diethylthiocarbamate Sulfoxide, which is an oxygenated metabolite of Disulfiram (Antabuse) that is capable of in vitro inactivation of liver mitochondrial aldehyde dehydrogenase.

备注
Moisture sensitive. Store away from bases, water/moisture and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas. Keep ignition sources away.

基本信息

MDL
MFCD00000636

EINECS
201-798-5

分子式
C5H10ClNO

分子量
135.59

熔点
-32°

沸点
186°

闪点
76°(168°F)

密度
1.070

折射率
1.4510

灵敏度
Moisture Sensitive. Store under Nitrogen. Ambient temperatures.

形态
Liquid

溶解性
Reacts with water.

Beilstein
506687

GHS危害和防范说明

GHS符号

Hazard Statements
H227-H302-H332-H315-H319-H351-H335
Combustible liquid.Harmful if swallowed.Harmful if inhaled.Causes skin irritation.Causes serious eye irritation.Suspected of causing cancer.May cause respiratory irritation.

Precautionary Statements
P210e-P201-P261-P305+P351+P338-P405-P501a
Obtain special instructions before use.Avoid breathing dust/fume/gas/mist/vapours/spray.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
8

包装组
III

危险类别
20/22-36/37/38-40
Harmful by inhalation and if swallowed.Irritating to eyes, respiratory system and skin.Limited evidence of a carcinogenic effect.

安全等级
26-36/37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves.

欧盟危险品标志

RTECS
FD4025000

TSCA

C11420Alfa AesarDiethylcarbamyl chloride99%796元/5ml;   1128元/500ml;   咨询

基本信息

Ref#
11420

MDL
636

分子式
C5 H10 Cl N O

分子量
135.59

闪点
80

密度
1.07

安全信息

危险等级
8

包装组
III

D91403Sigma-AldrichDiethylcarbamoyl Chloride97%304.42元/5 G;   305.1元/100 G;   1005.7元/500 G;   咨询

基本信息

线性分子式(C2H5)2NCOCl
分子量135.59
Beilstein506687
EC 号201-798-5
MDL编号MFCD00000636
PubChem化学物质编号24894257
NACRESNA.22

产品性质

质量水平200
测定97%
折射率n20/D 1.451 (lit.)
bp117-123 ℃/133 mmHg (lit.)
mp−32 ℃ (lit.)
密度1.07 g/mL at 25 ℃ (lit.)
SMILES stringCCN(CC)C(Cl)=O
InChI1S/C5H10ClNO/c1-3-7(4-2)5(6)8/h3-4H2,1-2H3
InChI keyOFCCYDUUBNUJIB-UHFFFAOYSA-N

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H302 + H332 - H315 - H319 - H335 - H351
预防措施声明P202 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313
危险分类Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码10 - Combustible liquids
WGKWGK 1
闪点(F)168.8 °F - closed cup
闪点(C)76 ℃ - closed cup
个人防护装备Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
050653FluorochemDiethylcarbamyl chloride>98.0%(GC)(T)220元/1g;   286元/25g;   704元/100g;   1848元/500g;   咨询

基本信息

CAS Number88-10-8
MDL NumberMFCD00000636
Density1.07

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H332: Harmful if inhaled.
H335: May cause respiratory irritation.
H351: Suspected of causing cancer ..
防范说明 P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P281: Use personal protective equipment as required.
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308 + P313: IF exposed or concerned: Get medical advice/ attention.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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