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CAS: 87958-67-6
分子式: C8H12N4OS2
分子量: 244.34
英文名称: 
cgp 52608
用途: CGP 52608 has been used as a RAR related orphan receptor α (RORα) synthetic agonist in THP-1 macrophages, in human monocyte cells THP1 and somatic testicular cells.
包装
推荐供应商
货号品牌产品名称规格包装、参考价格
C920924MACKLIN1-[3-烯丙基-4-氧代-噻唑烷-2-亚基]-4-甲基-硫代氨基脲≥98%1437元/5mg;   咨询
储存:−20°C
状态:固体
C5749Sigma-AldrichCGP 52608≥98%, solid1795.68元/5 MG;   5736.48元/25 MG;   咨询

产品说明

应用

CGP 52608 has been used as a RAR related orphan receptor α (RORα) synthetic agonist in THP-1 macrophages, in human monocyte cells THP1 and somatic testicular cells.

包装

5, 25 mg in glass bottle

生化/生理作用

CGP 52608 is a thiazolidine derivative and an antiarthritic compound. It possesses immunostimulatory functionality and elicits antiproliferative effect in colon tumors. It is cytotoxic towards neural cell lines. CGP 52608 induces apoptosis in tumor and also favors G0-G1 cell cycle phase accumulation in neural cell lines.
CGP 52608 is a specific activator of retinoic acid receptor-related orphan receptor α (RORA).

特点和优势

This compound is featured on the Nuclear Receptors (Non-Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式C8H12N4OS2
分子量244.34
MDL编号MFCD00942304
PubChem化学物质编号329775098
NACRESNA.77

产品性质

质量水平100
测定≥98%
形式solid
溶解性DMSO: >30 mg/mL
H2O: insoluble
储存温度−20℃
SMILES stringCNC(=S)N\N=C1/SCC(=O)N1CC=C
InChI1S/C8H12N4OS2/c1-3-4-12-6(13)5-15-8(12)11-10-7(14)9-2/h3H,1,4-5H2,2H3,(H2,9,10,14)/b11-8-
InChI keyDDYJDIHOSRTMSE-FLIBITNWSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
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