[登录] [免费注册]
试剂仪器网
位置:首页 > 资料中心 > 化工字典 > 875051-72-2
关键词:       仅模糊查询
CAS: 875051-72-2
分子式: C13H10Cl3N3O
分子量: 330.6
英文名称: 
pf-01247324
n-methyl-6-amino-5-(2,3,5-trichlorophenyl)pyridine-2-carboxamide
6-amino-n-methyl-5-(2,3,5-trichlorophenyl)-2-pyridinecarboxamide
6-amino-5-(2,3,5-trichlorophenyl)pyridine-2-carboxylic acid methylamide
pf-1247324
pf 01247324
用途: PF-01247324是选择性且有口服活性的Nav1.8通道阻断物,对人类重组Nav1.8 的IC50值为196 nM。
推荐供应商
货号品牌产品名称规格包装、参考价格
P876862MACKLINPF-01247324 ≥99%501元/5mg;   859元/10mg;   咨询
储存:2-8℃
PZ0274Sigma-AldrichPF-01247324≥98% (HPLC)1117.23元/5 MG;   4498.97元/25 MG;   咨询

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

In humans, PF-01247324 [6-amino-5-(2, 3, 5-trichloro-phenyl)-pyridine-2-carboxylic acid methylamide] prevents native tetrodotoxin-resistant (TTX-R) currents in dorsal root ganglion (DRG) neurons.
PF-01247324 is an orally bioavailable, selective and potent NaV1.8 channel blocker that inhibits that exhibits analgesic efficacy in rodent behavioral models of pain.

其他说明

This compound was developed by Pfizer for Ion Channel research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.

基本信息

经验(实验)分子式C13H10Cl3N3O
分子量330.60
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
manufacturer/tradenamePfizer®
颜色 white to beige
溶解性DMSO: 20 mg/mL, clear
创始人Pfizer
储存温度room temp

安全信息

象形图GHS06
警示用语:Danger
危险声明H301 - H315 - H319 - H335
预防措施声明P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
CAS号首数字顺序排列: 1 2 3 4 5 6 7 8 9