| CAS: | 871307-18-5 | ||
| 分子式: | C21H14ClFN6 | ||
| 分子量: | 404.8 | ||
| 英文名称: |
| ||
| 用途: | Tpl2 kinase inhibitor is a reversible inhibitor of tumor progression locus 2 |
| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 | ||||||||||||||||||||||||||||||||||||||
| T912898 | MACKLIN | Tpl2 Kinase Inhibitor | 98% | 3271元/1mg; | 展开 | ||||||||||||||||||||||||||||||||||||||
储存:-20°C,密闭,干燥 | |||||||||||||||||||||||||||||||||||||||||||
| 616373 | Sigma-Aldrich | Tpl2 Kinase Inhibitor-CAS 871307-18-5-Calbiochem | The Tpl2 Kinase Inhibitor, also referenced under CAS 871307-18-5, controls the biological activity of Tpl2 Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphory | 2741.8元/1 MG; | 展开 | ||||||||||||||||||||||||||||||||||||||
产品说明 一般描述 A cell-permeable naphthyridine compound that acts as a potent, reversible, and ATP-competitive inhibitor of Tpl2 kinase (IC50 = 50 nM). Displays significant selectivity over other related kinases (IC50 = 5, >40, 110, 180, >400 and >400 µM for EGFR, MEK, MK2, p38, Src, and PKC, respectively). Shown to inhibit LPS-induced TNF-α production both from primary human monocytes and in whole blood (IC50 = 700 nM and 8.5 µM, respectively). 包装 1 mg in Plastic ampoule 生化/生理作用 Cell permeable: yes 警告 Toxicity: Irritant (B) 重悬 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 其他说明 Gavrin, L.K., et al. 2005. Bioorg. Med. Chem. Lett.15, 5288. 法律信息 CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany 基本信息
产品性质
安全信息
| |||||||||||||||||||||||||||||||||||||||||||