CAS 870768-70-0; imb-808

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CAS:

870768-70-0

英文名称:

imb-808

n-methyl-n-(2-oxo-2-((2,3,4-trifluorophenyl)amino)ethyl)-3,4-dihydro-2h-benzo[b][1,4] dioxin-7-carboxamide

2,3-dihydro-n-methyl-n-[2-oxo-2-[(2,3,4-trifluorophenyl)amino]ethyl]-1,4-benzodioxin-6-carboxamide

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货号

品牌

产品名称

规格

包装、参考价格

SML1945

Sigma-Aldrich

IMB-808

≥98% (HPLC)

1048.99元/5 MG;

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产品说明

生化/生理作用

IMB-808 is a potent Liver X receptor α and β (LXRα/β) partial dual agonist that promotes expression of genes related to reverse cholesterol transport (including ABCA1 and ABCG1), and associated with cholesterol metabolism pathway in multiple cell lines (including ApoE). Also IMB-808 promotes cholesterol efflux from macrophages and reduced the accumulated lipids of foam cells.

基本信息

经验(实验)分子式	C₁₈H₁₅F₃N₂O₄
分子量	380.32

产品性质

测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 2 mg/mL, clear
储存温度	2-8℃
SMILES string	FC1=C(NC(CN(C)C(C2=CC(OCCO3)=C3C=C2)=O)=O)C=CC(F)=C1F

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

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