基本信息

技术规格

物性(参考值)

安全信息

图形或危害标志
信号词	危险
危险性说明	H303 : 吞咽可能有害。 H315 : 造成皮肤刺激。 H318 : 造成严重眼损伤。
防范说明	P264 : 作业后彻底清洗皮肤。 P280 : 戴防护手套/戴防护眼罩/戴防护面具。 P302 + P352 : 如皮肤沾染：用水充分清洗。 P312 : 如感觉不适，呼叫急救中心/医生。 P362+P364 : 脱掉沾污的衣服，清洗后方可重新使用。 P332 + P313 : 如发生皮肤刺激：求医/就诊。 P305 + P351 + P338 + P310 : 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。立即呼叫急救中心/医生。

相关法规

基本信息

安全信息

图形或危害标志
提示语	Danger
危险说明	H315 H318 H335
防范说明	P261 P280 P305+P351+P338
WGK	2
RTECS	NL7875000
TSCA	否

应用
5-Bromoisatin is used in the synthesis of N-derivatives of 5-bromoisatin, N-substituted pyrroles, linear polyaryleneoxindoles, 5-bromodioxindole, cinchoninic acid derivatives, 3-hydroxyoxindole, S-benzyldithiocarbazate Schiff Bases, 5-bromooxindole and Morita-Baylis-Hillman adducts of isatin derivatives. It is an indole derivative.

备注
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents.

基本信息

MDL
MFCD00149345

EINECS
201-747-7

分子式
C₈H₄BrNO₂

分子量
226.03

熔点
ca 250° dec.

灵敏度
Ambient temperatures.

形态
Powder

溶解性
Soluble in N,N dimethylformamide.

Beilstein
383760

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H318-H335
Causes skin irritation.Causes serious eye damage.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
37/38-41
Irritating to respiratory system and skin.Risk of serious damage to eyes.

安全等级
26-37/39
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable gloves and eye/face protection.

RTECS
NL7875000

TSCA
否

基本信息

Ref#
15423

MDL
5719

分子式
C8 H4 Br N O2

分子量
226.03

形态
Orange powder

产品说明

一般描述

5-溴异丁香素是一种5-卤代异丁香素。已被报道的合成方法之一是在SiO₂存在下使N-卤代糖精与靛红发生反应。它的正性肌力活动已在豚鼠的节律性刺激乳头肌上被研究。据报道，它在小鼠中以0.2g/kg的剂量可具有镇痛和镇静作用。

应用

5-溴异丁香素可用于合成：

• 5-溴异丁香素的N-衍生物
• N-取代的吡咯
• 线性聚亚芳基吲哚
• 5-溴二恶英
• 二辛可宁酸衍生物
• 3-羟基羟吲哚
• S-二硫代氨基甲酸苄酯席夫碱
• 5-溴羟吲哚
• 靛红衍生物的Morita-Baylis-Hillman加合物

包装

5, 25 g in glass bottle

基本信息

产品性质

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335
预防措施声明	P302 + P352 - P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 2
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves

基本信息

安全信息

图形或危害标志
危险性说明	H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation.
防范说明	P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing . P264: Wash hands thoroughly after handling. P271: Use only outdoors or in a well-ventilated area. P280: Wear . P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.. P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see relevant procedures. on this label). P332 + P313: If skin irritation occurs: Get medical advice/ attention. P337 + P313: If eye irritation persists: Get medical advice/attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362: Take off contaminated clothing and wash before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to in accordance with local regulation .