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CAS: 87-42-3
分子式: C5H3ClN4
分子量: 154.5585
熔点: 300℃
中文名称: 
6-氯嘌呤
6-氯代嘌呤
英文名称: 
6-chloro-purin
6-chloro-1h-purin
6-chloro-1h-purine
6-chloro-9h-purine
6-chloropurine
6-chlorpurine
clp
nsc 744
sk 6048
x 47
6-CP
展开更多英文名
性质描述: 淡黄色结晶。
用途: 嘌呤类产品中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
C795512MACKLIN6-氯嘌呤10mM in DMSO185元/1ml;   展开
储存:-20°C
C804141MACKLIN6-氯嘌呤99%26元/1g;   30元/5g;   68元/25g;   265元/100g;   980元/500g;   4000元/2.5kg;   展开
储存:2~8°C
状态:白色到黄色到米黄色或绿色粉末或晶体
C0278TCI6-Chloropurine>98.0%(T)640元/5G;   1340元/25G;   展开

基本信息

纯度/分析方法>98.0%(T)
分子式/分子量C5H3ClN4 = 154.56
外观与形状(20℃)固体
Reaxys-RN608606
PubChem物质ID87565432
SDBS (AIST Spectral DB)3393
Merck Index (14)2161
MDL编号MFCD00075825

技术规格

AppearanceWhite to Orange to Green powder to crystal
Purity(HPLC)min. 97.0 area%
Purity(Neutralization titration)min. 98.0 %
Solubility in hot Waterwithin almost transparency

安全信息

图形或危害标志
信号词警告
危险性说明H302 : 吞咽有害。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P270 : 使用本产品时不要进食、饮水或吸烟。
P264 : 作业后彻底清洗皮肤。
P301 + P312 + P330 : 如误吞咽:如感觉不适,呼叫急救中心/医生。漱口。

相关法规

RTECS#UO7520000
164043J&K6-Chloropurine98%641元/100G;   2453元/500G;   展开

基本信息

分子式C5H3ClN4
分子量154.56
熔点>300
MDL编码MFCD00075825
Beilstein608606
Merck14,2161
EINECS 编号201-745-6
存储条件Store at 2-8℃

安全信息

图形或危害标志
提示语Warning
危险说明H302
H315
H319
H335
防范说明P261
P280
P301+P312
P302+P352
P305+P351+P338
WGK3
RTECSUO7520000
A11202Alfa Aesar6-Chloropurine99%548元/1g;   1750元/5g;   8659元/25g;   展开

应用
6-Chloropurine is used in the preparation of 9-alkylpurines through alkylation with various substituted alkyl halides in dimethyl sulfoxide. It is also used to prepare 6-succinoaminopurine.

备注
Incompatible with strong oxidizing agents.

基本信息

MDL
MFCD00075825

EINECS
201-745-6

分子式
C5H3ClN4

分子量
154.56

熔点
>300° dec.

灵敏度
Ambient temperatures.

形态
Powder

溶解性
Soluble in hot water and dimethyl formamide.

Beilstein
5774

Merck
14,2161

GHS危害和防范说明

GHS符号

Hazard Statements
H302
Harmful if swallowed.

Precautionary Statements
P264-P270-P301+P312a-P330-P501a
Wash thoroughly after handling.Do not eat, drink or smoke when using this product.Do not eat, drink or smoke when using this product.Rinse mouth.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
22
Harmful if swallowed.

安全等级
36
Wear suitable protective clothing.

欧盟危险品标志

RTECS
UO7520000

TSCA

C17128Alfa Aesar6-Chloropurine99+%1176元/5g;   4962元/25g;   展开

基本信息

Ref#
17128

MDL
75825

分子式
C5 H3 Cl N4

分子量
154.56

形态
White/yellow/pale brown powder

161179Sigma-Aldrich6-Chloropurine≥99%603.54元/5 G;   展开

产品说明

一般描述

已研究 6-氯嘌呤与 3,4-二--O -乙酰基--D -木醛的酸催化反应。

应用

6-氯嘌呤在 DMSO 中通过各种取代卤代烷烃的烷基化反应制备 9-烷基嘌呤。也用于 6-琥珀氨基嘌呤的制备。

包装

5 g in glass bottle

基本信息

经验(实验)分子式C5H3ClN4
分子量154.56
Beilstein5774
EC 号201-745-6
MDL编号MFCD00075825
PubChem化学物质编号24849911
NACRESNA.22

产品性质

质量水平100
测定≥99%
形式powder
mp>300 ℃ (dec.) (lit.)
溶解性DMF: soluble 5%, clear, colorless to yellow
SMILES stringClc1ncnc2[nH]cnc12
InChI1S/C5H3ClN4/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H,7,8,9,10)
InChI keyZKBQDFAWXLTYKS-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
危险分类Acute Tox. 4 Oral
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
511617Sigma-Aldrich6-Chloropurine99%240.94元/5 G;   展开

产品说明

一般描述

6-Chloropurine (6-CIPH), a 6-substituted purine derivative, is an antileukemic drug. It can be prepared by the chlorination of hypoxanthine with phosphorus oxychloride in the presence of dimethylaniline. The NMR-based conformational analysis of the products formed during the reaction of 6-CIPH with 3,4-di-O-acetyl-D-xylal and 3,4-di-O-acetyl-L-arabinal have been reported. 6-CIPH can undergo palladium-catalyzed cross coupling with organostannanes at 6-position to form the corresponding arylated or alkylated products.

应用

6-Chloropurine may be used:

  • To prepare purine via catalytic dehydrogenation.
  • To prepare 9-alkylated adenines via Mitsunobu reaction with various alcohols.
  • As a starting material to synthesize dihydroisoxazole 6-chloropurine.

包装

5 g in glass bottle

基本信息

经验(实验)分子式C5H3ClN4
分子量154.56
Beilstein5774
EC 号201-745-6
MDL编号MFCD00075825
PubChem化学物质编号24873552

产品性质

质量水平100
测定99%
mp>300 ℃ (dec.) (lit.)
SMILES stringClc1ncnc2[nH]cnc12
InChI1S/C5H3ClN4/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H,7,8,9,10)
InChI keyZKBQDFAWXLTYKS-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
危险分类Acute Tox. 4 Oral
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
032518Fluorochem6-Chloropurine98%220元/10g;   308元/25g;   748元/100g;   2200元/500g;   展开

基本信息

CAS Number87-42-3
MDL NumberMFCD00075825
Melting Point>300℃

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: .
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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