CAS 869802-58-4; 9-(dimethylamino)-3-(hexahydro-1h-azepin-1-yl)-pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidin-4(3h)-one; a-841720

CAS:

869802-58-4

分子式:

C₁₇H₂₁N₅OS

分子量:

343.5

中文名称:

9-(dimethylamino)-3-(hexahydro-1h-azepin-1-yl)-pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidin-4(3h)-one

英文名称:

a-841720

用途:

A-841720 is a noncompetitive antagonist of the group 1 metabotropic glutamate receptor mGluR1 with an IC50 value of 10.7 nM for inhibition of L-glutamate-induced calcium release in 1321 N1 cells.

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

A911560

MACKLIN

A-841720

98%

1878元/1mg;

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储存：-20°C，密闭，干燥

SML0818

Sigma-Aldrich

A-841720

≥98% (HPLC)

4556.8元/25 MG;

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产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

A-841720 is a potent, selective, non-competitive mGluR1 antagonist that displays greater than 30-fold selectivity over another Group I metabotopic glutamate receptor, mGluR5. The compound has potent analgesic properties, and can also diminish motor and cognitive activity.

特点和优势

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式	C₁₇H₂₁N₅OS
分子量	343.45
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 15 mg/mL, clear
储存温度	2-8℃

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable