CAS 869296-13-9; t-26c

CAS:

869296-13-9

分子式:

C₂₄H₂₁N₃O₆S

分子量:

479.51

英文名称:

t-26c

4-[[[[2-[[[[3-(methyloxy)phenyl]methyl]amino]carbonyl]-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-5-yl]methyl]oxy]methyl]benzoic acid

4-[[[1,4-dihydro-2-[[[(3-methoxyphenyl)methyl]amino]carbonyl]-4-oxothieno[2,3-d]pyrimidin-5-yl]methoxy]methyl]-benzoic acid; 4-[[[[2-[[[[3-(methyloxy)phenyl]methyl]amino]carbonyl]-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-5-yl]methyl]oxy]methyl]benzoic acid

用途:

T-26c是高效和选择性的基质金属蛋白酶-13 (MMP-13) 抑制剂，IC50 值为6.75 pM。比对其他相关金属酶的选择性高2600倍。

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

详情

T798122

MACKLIN

T-26c

10mM in DMSO

648元/1ml;

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储存：-20°C

T910368

MACKLIN

T-26c

98%

1700元/10mg;

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储存：-20°C，密闭，干燥

SML1915

Sigma-Aldrich

T-26c

≥98% (HPLC)

1399.43元/5 MG; 4498.97元/25 MG;

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产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

T-26c is a highly potent, selective and cell-permeable matrix metalloproteinases 13 (MMP-13) inhibitor. T-26c inhibits the breakdown of collagen (87.4% inhibition at 0.1 μM) in IL-1b and oncostatin M stimulated cartilage. For full characterization details, please visit the T-26c probe summary on the Structural Genomics Consortium (SGC) website.

To learn about other SGC chemical probes for protein targets, visit sigma.com/sgc

特点和优势

T-26c is a chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC chemical probes, visit sigma.com/SGC.

基本信息

经验(实验)分子式	C₂₄H₂₁N₃O₆S
分子量	479.51

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 10 mg/mL, clear
储存温度	2-8℃
SMILES string	OC(C(C=C1)=CC=C1COCC2=CSC3=C2C(NC(C(NCC4=CC=CC(OC)=C4)=O)=N3)=O)=O

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3