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CAS: 86879-39-2
分子式: C12H16O5
分子量: 240.3
英文名称: 
3-carboxy-4-methyl-5-propyl-2-furanpropionic acid
用途: CMPF is highly albumin-bound and accumulates in the serum of uremic patients to concentrations in excess of 0.2 mM.
推荐供应商
货号品牌产品名称规格包装、参考价格详情
C912887MACKLINCMPF98%500元/1mg;   1200元/5mg;   4000元/25mg;   9999元/100mg;   展开
储存:-20°C,密闭,干燥
状态:白色粉末
90833Supelco3-Carboxy-4-methyl-5-propyl-2-furanpropanoic acidanalytical standard3678.29元/10 MG;   12435元/50 MG;   展开

产品说明

一般描述

3-Carboxy-4-methyl-5-propyl-2-furanpropanoic acid (CMPF), a major metabolite of furan fatty acids, is a uremic toxin (UT), excreted into the urine via organic,anion transporters under physiological conditions. It is mostly reported to be accumulated in chronic kidney disease (CKD) patients. Monitoring of CMPF may be important to predict organic anion transporting polypeptide (OATP)1B activity in CKD patients as studies have implicated a decreased trend in (OATP)1B activity in patients with this uremic toxin. It is also found to be in increased concentrations, for patients who progress from prediabetes to type 2 diabetes, patients with renal failure, polyunsaturated fatty acids with high-temperature cooking and subjects who consume fish or fish oil.

应用

3-Carboxy-4-methyl-5-propyl-2-furanpropanoic acid may be used as an analytical reference standard for the quantification of the analyte in human plasma samples using ultra-high performance liquid chromatography coupled to tandem mass spectrometry (UHPLC–MS/MS).

基本信息

经验(实验)分子式C12H16O5
分子量240.25
MDL编号MFCD08436079
NACRESNB.21

产品性质

等级analytical standard
质量水平100
测定≥95.0% (HPLC)
保质期limited shelf life, expiry date on the label
application(s)clinical testing
格式neat
储存温度2-8℃
SMILES stringOC(CCC1=C(C(O)=O)C(C)=C(CCC)O1)=O
InChI1S/C12H16O5/c1-3-4-8-7(2)11(12(15)16)9(17-8)5-6-10(13)14/h3-6H2,1-2H3,(H,13,14)(H,15,16)
InChI keyWMCQWXZMVIETAO-UHFFFAOYSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
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