CAS 864741-95-7; n-[2-(dimethylamino)ethyl]-n-[[4′-[[(2-phenylethyl)amino]methyl][1,1′-biphenyl]-4-yl]methyl]-cyclopentanepropanamide dihydrochloride; sb 699551 dihydrochloride

CAS:

864741-95-7

分子式:

C₃₄H₄₇Cl₂N₃O

分子量:

584.6625

中文名称:

n-[2-(dimethylamino)ethyl]-n-[[4′-[[(2-phenylethyl)amino]methyl][1,1′-biphenyl]-4-yl]methyl]-cyclopentanepropanamide dihydrochloride

英文名称:

sb 699551 dihydrochloride

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

S952913

MACKLIN

3-环戊基-N-(2-(二甲基氨基)乙基)-N-((4'-((苯乙基氨基)甲基)-[1,1'-联苯]-4-基)甲基)丙酰胺二盐酸盐

98%

1211元/1mg;

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储存：2-8°C

SML0853

Sigma-Aldrich

SB 699551 dihydrochloride

≥98% (HPLC)

1396.09元/5 MG; 5627.07元/25 MG;

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产品说明

应用

SB 699551 dihydrochloride has been used to identify the antagonism of 5-HT2AR in cell culture-derived hepatitis C virus (HCVcc).

包装

5, 25 mg in glass bottle

生化/生理作用

SB 699551 dihydrochloride is also known as (3-cyclopentyl-N-[2-(dimethylamino)ethyl]-N-[(4′-{[(2-phenylethyl)amino]methyl}-4-biphenylyl)methyl]propanamide dihydrochloride). It is considered as a useful tool to explain the physiological roles of the 5-ht5A receptor.
SB-699551 is a 5-HT5A receptor antagonist, (pKi = 8.3) with 100-fold selectivity over other 5-HT receptor populations. SB-699551 completely blocks 5-HT-induced [35S]GTPγS membrane binding in cells expressing recombinant guinea pig 5-HT-5A.

基本信息

经验(实验)分子式	C₃₄H₄₅N₃O · 2HCl
分子量	584.66
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	H₂O: 1 mg/mL, clear (warmed)
储存温度	2-8℃

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

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