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CAS: 86-98-6
分子式: C9H5Cl2N
分子量: 198.05
沸点: 148℃
熔点: 83-87℃
中文名称: 
4,7-二氯喹啉
英文名称: 
4,7-dichloroquinoline
4,7-dichloro-quinolin
tl 1473
Quinoline,4,7-dichloro-
性质描述: 针状结晶。熔点93℃,沸点148℃(1.33kPa)。
生产方法: 由7-氯-4-羟基喹啉氯化而得。
用途: 用作药物氯喹的中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
D830840MACKLIN4,7-二氯喹啉98%38元/25g;   145元/100g;   723元/500g;   展开
储存:室温,密封
状态:白色到浅棕色粉末
D1100TCI4,7-Dichloroquinoline>98.0%(GC)280元/25G;   展开

基本信息

纯度/分析方法>98.0%(GC)
分子式/分子量C9H5Cl2N = 198.05
外观与形状(20℃)固体
Reaxys-RN125359
PubChem物质ID87567663
SDBS (AIST Spectral DB)6268
MDL编号MFCD00006774

技术规格

AppearanceWhite to Orange to Green powder to crystal
Purity(GC)min. 98.0 %
Melting point85.0 to 88.0 ℃

物性(参考值)

熔点87 ℃
沸点148 ℃/10 mmHg

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。

相关法规

RTECS#VB4200000
610255J&K4,7-Dichloroquinoline99%83元/5G;   218元/25G;   718元/100G;   2872元/500G;   展开

基本信息

分子式C9H5Cl2N
分子量198.05
熔点81-83
MDL编码MFCD00006774
Beilstein125359
EINECS 编号201-714-7

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
防范说明P261
P305+P351+P338
WGK3
RTECSVB4200000
TSCA
A15985Alfa Aesar4,7-Dichloroquinoline98%688元/25g;   2396元/100g;   8894元/500g;   展开

应用
4,7-Dichloroquinoline is used as a drug chloroquine phosphate intermediate. It is also is used in the synthesis of hybrid aminoquinoline-triazine derivatives that show anti-microbial activity. In addition, it is used in the synthesis of novel oxazolidinones as anti-microbial agents showing efficacy against common bacterial strains.

备注
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents.

基本信息

MDL
MFCD00006774

EINECS
201-714-7

分子式
C9H5Cl2N

分子量
198.05

熔点
83-87°

沸点
148°/10mm

闪点
164°(327°F)

灵敏度
Ambient temperatures.

形态
Crystalline

溶解性
Insoluble in water.

Beilstein
125359

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

RTECS
VB4200000

TSCA

C11375Alfa Aesar4,7-Dichloroquinoline98%363元/5g;   729元/25g;   2110元/100g;   展开

基本信息

Ref#
11375

MDL
6774

分子式
C9 H5 Cl2 N

分子量
198.05

闪点
164

D74002Sigma-Aldrich4,7-Dichloroquinoline97%949.3元/100 G;   展开

基本信息

经验(实验)分子式C9H5Cl2N
分子量198.05
Beilstein125359
EC 号201-714-7
MDL编号MFCD00006774
PubChem化学物质编号24894130
NACRESNA.22

产品性质

质量水平100
测定97%
mp81-83 ℃ (lit.)
SMILES stringClc1ccc2c(Cl)ccnc2c1
InChI1S/C9H5Cl2N/c10-6-1-2-7-8(11)3-4-12-9(7)5-6/h1-5H
InChI keyHXEWMTXDBOQQKO-UHFFFAOYSA-N

安全信息

象形图GHS07GHS09
警示用语:Warning
危险声明H315 - H317 - H319 - H411
预防措施声明P261 - P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338
危险分类Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
141437Sigma-Aldrich4,7-Dichloroquinoline≥99%936.6元/25 G;   展开

产品说明

应用

4,7-Dichloroquinoline was used in the synthesis of piperaquine. It was used as starting reagent in the synthesis of {3-amino-5-[(7-chloro-4-quinolyl)amino]phenyl}methanol.

包装

25 g in poly bottle

基本信息

经验(实验)分子式C9H5Cl2N
分子量198.05
Beilstein125359
EC 号201-714-7
MDL编号MFCD00006774
PubChem化学物质编号24848499
NACRESNA.22

产品性质

质量水平100
测定≥99%
mp81-83 ℃ (lit.)
溶解性chloroform: soluble 50 mg/mL, clear, colorless to greenish-yellow
SMILES stringClc1ccc2c(Cl)ccnc2c1
InChI1S/C9H5Cl2N/c10-6-1-2-7-8(11)3-4-12-9(7)5-6/h1-5H
InChI keyHXEWMTXDBOQQKO-UHFFFAOYSA-N

安全信息

象形图GHS07GHS09
警示用语:Warning
危险声明H315 - H317 - H319 - H411
预防措施声明P261 - P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338
危险分类Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
PHR2438SupelcoChloroquine Related Compound APharmaceutical Secondary Standard; Certified Reference Material7687.08元/50 MG;   展开

产品说明

一般描述

Chloroquine Related Compound A is an impurity of chloroquine, a 9-aminoquinoline drug that effectively inhibits viral infections in humans.
Chloroquine Related Compound A is an impurity of chloroquine, which is a 9-aminoquinoline drug that effectively inhibits viral infections in humans.

应用

Chloroquine Related Compound A can be used as a pharmaceutical primary standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography (LC) technique.
Chloroquine Related Compound A can be used as a pharmaceutical secondary standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography (LC) technique.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC4608 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C9H5Cl2N
分子量198.05
Beilstein125359
MDL编号MFCD00006774

产品性质

生物来源synthetic
等级certified reference material
pharmaceutical secondary standard
agencyBP
EP
USP
蒸汽压0.0000811 kPa ( 25 ℃)
形式crystalline
包装pkg of 50 mg
颜色 white to brown
pH值(酸碱度)3.86 (24.9 ℃)
bp298.4 °F (148℃)
mp81-83 ℃ (lit.)
溶解性water: slightly soluble 0.037 g/L at 25 ℃
ethanol: freely soluble
ether: freely soluble
密度1.31 g/cm3 at 20 ℃ (971.4 hPa)
application(s)pharmaceutical
药典可追溯性traceable to USP 1118328
储存温度2-30℃
SMILES stringClc1ccc2c(Cl)ccnc2c1
InChI1S/C9H5Cl2N/c10-6-1-2-7-8(11)3-4-12-9(7)5-6/h1-5H
InChI keyHXEWMTXDBOQQKO-UHFFFAOYSA-N

安全信息

象形图GHS07GHS09
警示用语:Warning
危险声明H315 - H317 - H319 - H411
预防措施声明P261 - P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338
危险分类Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
078074Fluorochem4,7-Dichloroquinoline95%418元/25g;   1628元/100g;   7854元/1kg;   展开

基本信息

CAS Number86-98-6
MDL NumberMFCD00006774

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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