| CAS: | 853220-52-7 | |||||
| 分子式: | C19H18N4O3 | |||||
| 分子量: | 350.37 | |||||
| 中文名称: |
| |||||
| 英文名称: |
| |||||
| 用途: | Wnt agonist 1是具有细胞透性的Wnt信号通路激活剂，诱导依赖于β-catenin-和TCF-的转录活性，EC50为0.7 μM。Wnt agonist 1并没有抑制GSK-3β活性，可能作为有用的工具用于Wnt通路参与的生理过程的研究[1]。将hCMEC/D3 cells暴露于Wnt agonist 1将引起具有核或核周β-catenin表达的细胞比例增多（10或20 μM, 16 h）[2]。 |
| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | |||||||||||||||||||||||||||||||||||||
| W872522 | MACKLIN | Wnt agonist 1 | 99% | 235元/5mg; 495元/25mg; 1255元/100mg; | 咨询 | ||||||||||||||||||||||||||||||||||||
储存：-20℃ 状态：白色到黄色固体 | |||||||||||||||||||||||||||||||||||||||||
| W793357 | MACKLIN | Wnt agonist 1 | 10mM in DMSO | 650元/1ml; | 咨询 | ||||||||||||||||||||||||||||||||||||
储存：-20°C | |||||||||||||||||||||||||||||||||||||||||
| 681664 | Sigma-Aldrich | Wnt Agonist I in DMSO-CAS 853220-52-7-Calbiochem | The Wnt Agonist I in DMSO, also referenced under CAS 853220-52-7, controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Cancer applications. | 1306.9元/2 MG; | 咨询 | ||||||||||||||||||||||||||||||||||||
产品说明 一般描述 A cell-permeable, potent, and selective activator of Wnt signaling that does not inhibit the activity of GSK-3β (IC50 >60 µM). Shown to mimic the effect of Wnt and induce β-catenin and TCF (T-cell fate)-dependent transcriptional activity (EC50 = 700 nM in HEK-293T cells). Reported to cause substantial head defects during Xenopus embryonic development. The solid form of this compound (Cat. No. 681665) is also available. 包装 2 mg in Glass bottle 生化/生理作用 Cell permeable: yes 警告 Toxicity: Irritant (B) 外形 A 25 mM (2 mg/228 µL) solution of Wnt Agonist I (Cat. No. 681665) in DMSO. 重悬 Following initial thaw, aliquot and freeze (-70°C). Aliquots are stable for up to 6 months at -70°C. 其他说明 Liu, J., et al. 2005. Angew. Chem. Int. Ed.44, 1987. 法律信息 CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany 基本信息
产品性质
安全信息
| |||||||||||||||||||||||||||||||||||||||||
| 681665 | Sigma-Aldrich | Wnt Agonist-CAS 853220-52-7-Calbiochem | The Wnt Agonist, also referenced under CAS 853220-52-7, controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Cancer applications. | 3298.89元/5 MG; | 咨询 | ||||||||||||||||||||||||||||||||||||
产品说明 一般描述 A cell-permeable, potent, and selective activator of Wnt signaling that does not inhibit the activity of GSK-3β (IC50 >60 µM). Shown to mimic the effect of Wnt and induce β-catenin and TCF (T-cell fate)-dependent transcriptional activity (EC50 = 700 nM in HEK-293T cells). Reported to cause substantial head defects during Xenopus embryonic development. 包装 5 mg in Plastic ampoule 生化/生理作用 Cell permeable: yes 警告 Toxicity: Standard Handling (A) 重悬 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. 其他说明 Liu, J., et al. 2005. Angew. Chem. Int. Ed.44, 1987. 法律信息 CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany 基本信息
产品性质
安全信息
| |||||||||||||||||||||||||||||||||||||||||
| SML0698 | Sigma-Aldrich | CID 11210285 hydrochloride | ≥98% (HPLC) | 1179.67元/5 MG; 4556.8元/25 MG; | 咨询 | ||||||||||||||||||||||||||||||||||||
产品说明 应用 CID 11210285 hydrochloride has been used as a Wnt agonist. 包装 5, 25 mg in glass bottle 生化/生理作用 CID 11210285 is a cell-permeable, potent and selective activator of Wnt signaling without inhibiting GSK-3β. CID 11210285is a Wnt agonist. 其他说明 Light sensitve and air sensitive. 基本信息
产品性质
安全信息
| |||||||||||||||||||||||||||||||||||||||||
| 431587 | Fluorochem | N4-(Benzo[d][1,3]dioxol-5-ylmethyl)-6-(3-methoxyphenyl)pyrimidine-2,4-diamine | 95% | 4862元/250mg; 12122元/1g; | 咨询 | ||||||||||||||||||||||||||||||||||||
基本信息
| |||||||||||||||||||||||||||||||||||||||||
m.cnreagent.com
