| CAS: | 852045-46-6 | |||
| 分子式: | C21H23N3OS | |||
| 分子量: | 365.5 | |||
| 英文名称: |
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| 用途: | FLT3 Inhibitor III is a potent inhibitor of Fms-like tyrosine kinase 3 |
| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | |||||||||||||||||||||||||||||||||
| F912837 | MACKLIN | FLT3 Inhibitor III | 98% | 3083元/5mg; | 咨询 | ||||||||||||||||||||||||||||||||
储存：-20°C，密闭，干燥 | |||||||||||||||||||||||||||||||||||||
| 343022 | Sigma-Aldrich | Flt-3 Inhibitor III-CAS 852045-46-6-Calbiochem | The Flt-3 Inhibitor III, also referenced under CAS 852045-46-6, controls the biological activity of Flt-3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation a | 3736.22元/5 MG; | 咨询 | ||||||||||||||||||||||||||||||||
产品说明 一般描述 A cell-permeable 5-phenyl-2-thiazolamine compound that acts as a potent, ATP binding site-targeting inhibitor of Flt3 (IC50 = 50 nM). It inhibits c-Kit, KDR, c-Abl, Cdk1, c-Src, and Tie-2 only at much higher concentrations (IC50 = 0.26, 0.91, 1.2, 2.1, 2.8, and 8.0 µM, respectively) and exhibits little activity against a panel of 12 other commonly studied kinases even at concentrations as high as 10 µM. Blocks FLT3-dependent cell proliferation in a dose-dependent manner (IC50 = 52, 240, and 760 nM in MV4:11-ITD, BaF3-ITD, and BaF3-D835/Y cells). 包装 5 mg in Plastic ampoule 生化/生理作用 Cell permeable: yes 警告 Toxicity: Harmful (C) 重悬 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. 其他说明 Furet, P., et al. 2006. J. Med. Chem.49, 4451. 法律信息 CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany 基本信息
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