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CAS: 84692-91-1
分子式: C15H18O3
分子量: 246.3
中文名称: 
阿格拉宾
英文名称: 
arglabin
用途: Arglabin由亮绿蒿中提取获得的天然产物,具有抗癌活性。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
A860597MACKLIN阿格拉宾≥95%160元/1mg;   460元/5mg;   738元/10mg;   展开
储存:-20°C
A914624MACKLIN阿格拉宾分析对照品,98%580元/5mg;   展开
储存:-20°C
状态:白色到灰白色固体
A3449TCIArglabin>98.0%(HPLC)1990元/5MG;   展开

基本信息

纯度/分析方法>98.0%(HPLC)
分子式/分子量C15H18O3 = 246.31
外观与形状(20℃)固体
储存温度-20℃
应避免的情况光,加热
Reaxys-RN3549528
MDL编号MFCD11519463

技术规格

AppearanceWhite to Light yellow powder to crystal
Purity(HPLC)min. 98.0 area%
Specific rotation+101 to +104 deg (C=0.3, CHCl3)
NMRconfirm to structure

物性(参考值)

熔点102 ℃
SML1570Sigma-AldrichArglabin≥98% (HPLC)1396.09元/1 MG;   4498.97元/5 MG;   展开

产品说明

包装

1, 5 mg in glass bottle

生化/生理作用

Arglabin is a natural product with antitumor and anti-inflammatory activity. Arglabin competitively inhibits the binding of farnesyl diphosphate to farnesyl transferase (FTase), preventing the activation of RAS proto-oncogene by preventing the incorporation of farnesyl pyrophosphate into human H-ras proteins. Arglabin is also an inhibitor of the NLRP3 inflammasome. Arglabin reduces inflammation and plasma lipids and has shown a marked reduction in atherosclerotic lesions.

基本信息

经验(实验)分子式C15H18O3
分子量246.30
NACRESNA.77

产品性质

质量水平100
生物来源semisynthetic (from parthenolide)
测定≥98% (HPLC)
形式powder
储存条件protect from light
颜色 white to beige
储存温度−20℃
InChI1S/C15H18O3/c1-8-4-7-15-11(8)12-10(9(2)13(16)17-12)5-6-14(15,3)18-15/h4,10-12H,2,5-7H2,1,3H3/t10-,11-,12-,14-,15+/m0/s1
InChI keyUVJYAKBJSGRTHA-ZCRGAIPPSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 - H315 - H319 - H335
预防措施声明P301 + P312 + P330 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
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