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CAS: 84680-54-6
分子式: C18H24N2O5·2H2O
分子量: 348.42
熔点: 151-159 °C
用途: Enalaprilat Dihydrate是一种新型血管紧张肽转化酶(ACE)抑制剂，IC50为1.2 nM。
推荐供应商
货号品牌产品名称规格包装、参考价格
E794342MACKLINEnalaprilat Dihydrate10mM in DMSO735元/1ml;   咨询
储存：-20°C
E863798MACKLINEnalaprilat Dihydrate97%453元/50mg;   咨询
储存：2-8°C
状态：白色-极淡的黄色晶体-粉末
E1302TCIEnalaprilat Dihydrate>98.0%(HPLC)590元/50MG;   1890元/250MG;   咨询

基本信息

纯度/分析方法>98.0%(HPLC)
分子式/分子量C18H24N2O5・2H2O = 384.43
外观与形状(20℃)固体
储存温度0-10℃
应避免的情况加热
Reaxys-RN14568894
PubChem物质ID354335632

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 98.0 area%
Elemental analysis(Nitrogen)6.80 to 7.80 %
Specific rotation [a]20/D-50.0 to -54.0 deg(C=1, MeOH(calcd.on anh.substance))
Water8.0 to 11.0 %

相关法规

RTECS#TW3590600
Y0000615Enalaprilat DihydrateEuropean Pharmacopoeia (EP) Reference Standard1277.32元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

Enalaprilat is an inhibitor of angiotensin converting enzyme (ACE), antihypertensive, and a Bradykinin B1 receptor activator. Enalaprilat has nM potency versus ACE and also activates B1 receptors to release NO.

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C18H24N2O5 ·2H2O
分子量384.42
MDL编号MFCD00941393
PubChem化学物质编号329831050
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringO.O.C[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N2CCC[C@H]2C(O)=O
InChI1S/C18H24N2O5.2H2O/c1-12(16(21)20-11-5-8-15(20)18(24)25)19-14(17(22)23)10-9-13-6-3-2-4-7-13;;/h2-4,6-7,12,14-15,19H,5,8-11H2,1H3,(H,22,23)(H,24,25);2*1H2/t12-,14-,15-;;/m0../s1
InChI keyMZYVOFLIPYDBGD-MLZQUWKJSA-N
Gene Informationhuman ... ACE(1636)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
E9658Sigma-AldrichEnalaprilat Dihydrate≥98% (HPLC)1649.92元/5 MG;   6225.22元/25 MG;   咨询

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

Enalapril, the ethyl ester of enalaprilat exhibits slight pharmacological activity until it is hydrolyzed in the liver to enalaprilat. Enalaprilat, a IV form of an angiotensin-converting-enzyme inhibitor (ACE) prevents the transformation of angiotensin I to angiotensin II, a potent vasoconstrictor.
Enalaprilat is an inhibitor of angiotensin converting enzyme (ACE), antihypertensive, and a Bradykinin B1 receptor activator. Enalaprilat has nM potency versus ACE and also activates B1 receptors to release NO.

特点和优势

This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
This compound is featured on the Angiotensin Receptors and Bradykinin Receptors pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式C18H24N2O5 ·2H2O
分子量384.42
EC 号278-459-3
MDL编号MFCD00941393
PubChem化学物质编号329799089
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
溶解性H2O: 14 mg/mL at 60 ℃ (warming for 5 minutes)
DMSO: 64 mg/mL
创始人Merck & Co., Inc., Kenilworth, NJ, U.S.
储存温度room temp
SMILES stringO.O.C[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N2CCC[C@H]2C(O)=O
InChI1S/C18H24N2O5.2H2O/c1-12(16(21)20-11-5-8-15(20)18(24)25)19-14(17(22)23)10-9-13-6-3-2-4-7-13;;/h2-4,6-7,12,14-15,19H,5,8-11H2,1H3,(H,22,23)(H,24,25);2*1H2/t12-,14-,15-;;/m0../s1
InChI keyMZYVOFLIPYDBGD-MLZQUWKJSA-N
Gene Informationhuman ... ACE(1636)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
1235274USPEnalaprilatUnited States Pharmacopeia (USP) Reference Standard3828.99元/300 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

Enalaprilat is an inhibitor of angiotensin converting enzyme (ACE), antihypertensive, and a Bradykinin B1 receptor activator. Enalaprilat has nM potency versus ACE and also activates B1 receptors to release NO.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C18H24N2O5 ·2H2O
分子量384.42
MDL编号MFCD00941393
PubChem化学物质编号329749718
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringO.O.C[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N2CCC[C@H]2C(O)=O
InChI1S/C18H24N2O5.2H2O/c1-12(16(21)20-11-5-8-15(20)18(24)25)19-14(17(22)23)10-9-13-6-3-2-4-7-13;;/h2-4,6-7,12,14-15,19H,5,8-11H2,1H3,(H,22,23)(H,24,25);2*1H2/t12-,14-,15-;;/m0../s1
InChI keyMZYVOFLIPYDBGD-MLZQUWKJSA-N
Gene Informationhuman ... ACE(1636)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
BP742EnalaprilatBritish Pharmacopoeia (BP) Reference Standard1916.08元/20 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

Enalaprilat is an inhibitor of angiotensin converting enzyme (ACE), antihypertensive, and a Bradykinin B1 receptor activator. Enalaprilat has nM potency versus ACE and also activates B1 receptors to release NO.

包装

Unit quantity: 20 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C18H24N2O5 ·2H2O
分子量384.42
MDL编号MFCD00941393

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameBP
格式neat
储存温度2-8℃
SMILES stringO.O.C[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N2CCC[C@H]2C(O)=O
InChI1S/C18H24N2O5.2H2O/c1-12(16(21)20-11-5-8-15(20)18(24)25)19-14(17(22)23)10-9-13-6-3-2-4-7-13;;/h2-4,6-7,12,14-15,19H,5,8-11H2,1H3,(H,22,23)(H,24,25);2*1H2/t12-,14-,15-;;/m0../s1
InChI keyMZYVOFLIPYDBGD-MLZQUWKJSA-N
Gene Informationhuman ... ACE(1636)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
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