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关键词:       仅模糊查询
CAS: 83915-83-7
分子式: C21H35N3O7
分子量: 405.50(as Anhydrous)
中文名称: 
赖诺普利
英文名称: 
1-(n(sup 2)-(1-carboxy-3-phenylpropyl)-l-lysyl)-, dihydrate, (S)-l-prolin
(ds)-1-[n2-(1-carboxy-3-phenylpropyl)-l-proline dihydrate
(S)-1-(n(sup 2)-(1-carboxy-3-phenylpropyl)-l-lysyl)-l-proline dihydrate
acerbon
carace
mk-521
novatec
renacor
vivatec
性质描述: 白色结晶性粉末。
用途: 血管紧张素转换酶抑制剂（ACEI）类的抗高血压药。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
L797907MACKLIN赖诺普利二水合物10mM in H2O544元/1ml;   展开
储存：-20°C
L0220TCILisinopril Dihydrate>98.0%(T)140元/1G;   390元/5G;   展开

基本信息

纯度/分析方法>98.0%(T)
分子式/分子量C21H31O5N3・2H2O = 441.53
外观与形状(20℃)固体
储存温度0-10℃
应避免的情况加热
Reaxys-RN4276619
PubChem物质ID87560323
Merck Index (14)5516
MDL编号MFCD01698825

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(Nonaqueous Titration)min. 98.0 %
Specific rotation [a]20/D-42.0 to -48.0 deg(C=1, 0.25mol/L Zinc Acetate buffer sol.)(calcd.on anh.substance)
Water8.0 to 9.5 %

物性(参考值)

熔点148 ℃
比旋光度 [α]D-45° (C=1,0.25mol/L ZnAcetate Buff. sol.)

相关法规

RTECS#TW3589990
C46261Alfa AesarLisinopril Dihydrate945元/1g;   3105元/5g;   展开

基本信息

Ref#
46261

分子式
C21H31N3O5.2H2O

分子量
467.41

GHS危害和防范说明

Hazard Statements
H319 H360 H373

Precautionary Statements
P264 P201 P280 P308+P313

PHR1143SupelcoLisinoprilPharmaceutical Secondary Standard; Certified Reference Material1105.99元/1 G;   展开

产品说明

一般描述

Lisinopril is a lysine derivative of enalaprilat and belongs to the group of angiotensin converting enzyme (ACE) inhibitors. It is widely used as an orally active medication in the treatment of high blood pressure and may be used to treat congestive heart failure.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Lisinopril may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using kinetic spectrophotometric technique.

生化/生理作用

血管紧张素转换酶(ACE)抑制剂。

分析说明

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他说明

Values of analytes vary lot to lot.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAB3302 in the slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C21H31O5N3 · 2H2O
分子量441.52
MDL编号MFCD01698825
PubChem化学物质编号329823163
NACRESNA.24

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to BP 695
traceable to PhEur L0702000
traceable to USP 1368609
储存温度2-30℃
SMILES string[H]O[H].[H]O[H].NCCCC[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N2CCC[C@H]2C(O)=O
InChI1S/C21H31N3O5.2H2O/c22-13-5-4-9-16(19(25)24-14-6-10-18(24)21(28)29)23-17(20(26)27)12-11-15-7-2-1-3-8-15;;/h1-3,7-8,16-18,23H,4-6,9-14,22H2,(H,26,27)(H,28,29);2*1H2/t16-,17-,18-;;/m0../s1
InChI keyCZRQXSDBMCMPNJ-ZUIPZQNBSA-N
Gene Informationhuman ... ACE(1636)

安全信息

象形图GHS08
警示用语：Danger
危险声明H360D - H373
预防措施声明P202 - P260 - P280 - P308 + P313 - P405 - P501
危险分类Repr. 1A - STOT RE 2
靶器官Kidney
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
L6292Sigma-AldrichLisinopril≥98% (HPLC)4932.16元/100 MG;   8361.84元/250 MG;   展开

产品说明

应用

赖诺普利已被用于研究杜氏营养不良症小鼠的抗纤维化作用。它已被用于研究经过长期达贝泊汀处理后的 TGR(mRen2)27 (携带小鼠 Ren-2 基因的转基因大鼠)大鼠的肾结构和功能的变化。

包装

100, 250 mg in glass bottle

生化/生理作用

血管紧张素转换酶(ACE)抑制剂。

特点和优势

该化合物是位于美国新泽西Kenilworth的Merck & Co., Inc.开发。想要浏览其他由制药公司开发的化合物以及已批准药物/候选药物清单， 请单击此处。

基本信息

经验(实验)分子式C21H31O5N3 · 2H2O
分子量441.52
MDL编号MFCD01698825
PubChem化学物质编号329817636
NACRESNA.32

产品性质

质量水平100
测定≥98% (HPLC)
形式solid
颜色 white
溶解性H2O: ≥10 mg/mL
DMSO: ~6.5 mg/mL (with heating and sonicating)
储存温度2-8℃
SMILES string[H]O[H].[H]O[H].NCCCC[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N2CCC[C@H]2C(O)=O
InChI1S/C21H31N3O5.2H2O/c22-13-5-4-9-16(19(25)24-14-6-10-18(24)21(28)29)23-17(20(26)27)12-11-15-7-2-1-3-8-15;;/h1-3,7-8,16-18,23H,4-6,9-14,22H2,(H,26,27)(H,28,29);2*1H2/t16-,17-,18-;;/m0../s1
InChI keyCZRQXSDBMCMPNJ-ZUIPZQNBSA-N
Gene Informationhuman ... ACE(1636)

安全信息

象形图GHS08
警示用语：Danger
危险声明H360 - H373
预防措施声明P201 - P308 + P313
危险分类Repr. 1A - STOT RE 2
靶器官Kidney
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
L0702000Lisinopril DihydrateEuropean Pharmacopoeia (EP) Reference Standard1572.27元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

血管紧张素转换酶(ACE)抑制剂。

包装

Unit quantity: 50 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C21H31O5N3 · 2H2O
分子量441.52
MDL编号MFCD01698825
PubChem化学物质编号329817371
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES string[H]O[H].[H]O[H].NCCCC[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N2CCC[C@H]2C(O)=O
InChI1S/C21H31N3O5.2H2O/c22-13-5-4-9-16(19(25)24-14-6-10-18(24)21(28)29)23-17(20(26)27)12-11-15-7-2-1-3-8-15;;/h1-3,7-8,16-18,23H,4-6,9-14,22H2,(H,26,27)(H,28,29);2*1H2/t16-,17-,18-;;/m0../s1
InChI keyCZRQXSDBMCMPNJ-ZUIPZQNBSA-N
Gene Informationhuman ... ACE(1636)

安全信息

象形图GHS08
警示用语：Danger
危险声明H360 - H373
预防措施声明P201 - P308 + P313
危险分类Repr. 1A - STOT RE 2
靶器官Kidney
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
Y0001701Lisinopril for peak identificationEuropean Pharmacopoeia (EP) Reference Standard1572.27元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

血管紧张素转换酶(ACE)抑制剂。

包装

Unit quantity: 10 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C21H31O5N3 · 2H2O
分子量441.52
MDL编号MFCD01698825
PubChem化学物质编号329830790
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES string[H]O[H].[H]O[H].NCCCC[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N2CCC[C@H]2C(O)=O
InChI1S/C21H31N3O5.2H2O/c22-13-5-4-9-16(19(25)24-14-6-10-18(24)21(28)29)23-17(20(26)27)12-11-15-7-2-1-3-8-15;;/h1-3,7-8,16-18,23H,4-6,9-14,22H2,(H,26,27)(H,28,29);2*1H2/t16-,17-,18-;;/m0../s1
InChI keyCZRQXSDBMCMPNJ-ZUIPZQNBSA-N
Gene Informationhuman ... ACE(1636)

安全信息

象形图GHS08
警示用语：Danger
危险声明H360 - H373
预防措施声明P201 - P308 + P313
危险分类Repr. 1A - STOT RE 2
靶器官Kidney
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
Y0001709Lisinopril for system suitability AEuropean Pharmacopoeia (EP) Reference Standard1572.27元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

血管紧张素转换酶(ACE)抑制剂。

包装

Unit quantity: 15 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C21H31O5N3 · 2H2O
分子量441.52
MDL编号MFCD01698825
PubChem化学物质编号329830795
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES string[H]O[H].[H]O[H].NCCCC[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N2CCC[C@H]2C(O)=O
InChI1S/C21H31N3O5.2H2O/c22-13-5-4-9-16(19(25)24-14-6-10-18(24)21(28)29)23-17(20(26)27)12-11-15-7-2-1-3-8-15;;/h1-3,7-8,16-18,23H,4-6,9-14,22H2,(H,26,27)(H,28,29);2*1H2/t16-,17-,18-;;/m0../s1
InChI keyCZRQXSDBMCMPNJ-ZUIPZQNBSA-N
Gene Informationhuman ... ACE(1636)

安全信息

象形图GHS08
警示用语：Danger
危险声明H360 - H373
预防措施声明P201 - P308 + P313
危险分类Repr. 1A - STOT RE 2
靶器官Kidney
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
1368609USPLisinoprilUnited States Pharmacopeia (USP) Reference Standard3231.47元/300 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

血管紧张素转换酶(ACE)抑制剂。

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C21H31O5N3 · 2H2O
分子量441.52
MDL编号MFCD01698825
PubChem化学物质编号329750250
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
SMILES string[H]O[H].[H]O[H].NCCCC[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N2CCC[C@H]2C(O)=O
InChI1S/C21H31N3O5.2H2O/c22-13-5-4-9-16(19(25)24-14-6-10-18(24)21(28)29)23-17(20(26)27)12-11-15-7-2-1-3-8-15;;/h1-3,7-8,16-18,23H,4-6,9-14,22H2,(H,26,27)(H,28,29);2*1H2/t16-,17-,18-;;/m0../s1
InChI keyCZRQXSDBMCMPNJ-ZUIPZQNBSA-N
Gene Informationhuman ... ACE(1636)

安全信息

象形图GHS08
警示用语：Danger
危险声明H360 - H373
预防措施声明P201 - P202 - P260 - P280 - P308 + P313 - P405
危险分类Repr. 1A - STOT RE 2
靶器官Kidney
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
BP695Lisinopril DihydrateBritish Pharmacopoeia (BP) Reference Standard2189.77元/100 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

血管紧张素转换酶(ACE)抑制剂。

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C21H31O5N3 · 2H2O
分子量441.52
MDL编号MFCD01698825
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameBP
格式neat
储存温度2-8℃
SMILES string[H]O[H].[H]O[H].NCCCC[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N2CCC[C@H]2C(O)=O
InChI1S/C21H31N3O5.2H2O/c22-13-5-4-9-16(19(25)24-14-6-10-18(24)21(28)29)23-17(20(26)27)12-11-15-7-2-1-3-8-15;;/h1-3,7-8,16-18,23H,4-6,9-14,22H2,(H,26,27)(H,28,29);2*1H2/t16-,17-,18-;;/m0../s1
InChI keyCZRQXSDBMCMPNJ-ZUIPZQNBSA-N
Gene Informationhuman ... ACE(1636)

安全信息

象形图GHS08
警示用语：Danger
危险声明H360 - H373
预防措施声明P201 - P308 + P313
危险分类Repr. 1A - STOT RE 2
靶器官Kidney
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
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