CAS 83643-88-3; (S)-a-amino-3-hydroxy-5-methylisoxazole -4-propio

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货号

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产品名称

规格

包装、参考价格

详情

S919186

MACKLIN

（S）-α-氨基-3-羟基-5-甲基异恶唑-4-丙酸

≥98%

2381元/1mg; 8243元/5mg;

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储存：2-8°C,密封,干燥

A0326

Sigma-Aldrich

(S)-AMPA

≥98%

2975.64元/1 MG; 10300.4元/5 MG;

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产品说明

一般描述

AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) activates excitatory postsynaptic currents (EPSC).

应用

(S)-AMPA has also been used to activate rostromedial tegmental nucleus (RMTg), to study aversive conditioning in relation with cocaine-induced avoidance behaviors in mice.
(S)-AMPA has been used to selectively eliminate the neural cochlear component of adult barn owls by destroying afferent synapses.

生化/生理作用

Active enantiomer of (RS)-AMPA zwitterion. Potent agonist at the AMPA subclass of ionotropic glutamate receptors.

特点和优势

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式	C₇H₁₀N₂O₄
分子量	186.17
MDL编号	MFCD00672630
PubChem化学物质编号	24890421
NACRES	NA.77

产品性质

质量水平	100
测定	≥98%
SMILES string	Cc1onc(O)c1C[C@H](N)C(O)=O
InChI	1S/C7H10N2O4/c1-3-4(6(10)9-13-3)2-5(8)7(11)12/h5H,2,8H2,1H3,(H,9,10)(H,11,12)/t5-/m0/s1
InChI key	UUDAMDVQRQNNHZ-YFKPBYRVSA-N
Gene Information	human ... GRIA1(2890), GRIA2(2891), GRIA4(2893), GRIK1(2897) mouse ... Gria1(14799) rat ... Gria1(50592), Gria2(29627), Gria3(29628), Gria4(29629), Grik1(29559), Grik2(54257), Grik4(24406), Grin2a(24409), Grin2b(24410), Grm6(24419)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)

M01254

Fluorochem

(S)-alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

99%

1738元/1mg; 3498元/5mg; 5610元/10mg;

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基本信息

CAS Number	83643-88-3
MDL Number	MFCD00672630

安全信息

图形或危害标志
危险性说明	H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation.
防范说明	P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing . P264: Wash hands thoroughly after handling. P271: Use only outdoors or in a well-ventilated area. P280: Wear . P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.. P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see relevant procedures. on this label). P332 + P313: If skin irritation occurs: Get medical advice/ attention. P337 + P313: If eye irritation persists: Get medical advice/attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362: Take off contaminated clothing and wash before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to in accordance with local regulation .