| CAS: | 832115-62-5 | |
| 分子式: | C11H10N2O2S | |
| 分子量: | 234.27 | |
| 英文名称: |
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| 用途: | Isoxazole 9 (Isx-9)是一种成体神经发生的合成促进剂，通过引起成熟神经干细胞/前体细胞(NSPCs)的神经元分化而发挥作用。 |
| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | |||||||||||||||||||||||||||||||||
| I873002 | MACKLIN | Isoxazole 9 (ISX-9) | 99% | 353元/5mg; 858元/25mg; | 咨询 | ||||||||||||||||||||||||||||||||
储存：-20℃ 状态：白色到灰色到黄色固体 | |||||||||||||||||||||||||||||||||||||
| I795690 | MACKLIN | Isoxazole 9 (ISX-9) | 10mM in DMSO | 652元/1ml; | 咨询 | ||||||||||||||||||||||||||||||||
储存：-20°C | |||||||||||||||||||||||||||||||||||||
| 480743 | Sigma-Aldrich | Neuronal Differentiation Inducer III-CAS 832115-62-5-Calbiochem | A cell-permeable isoxazole compound that selectively induces robust neuronal differentiation (Effective concentration = 20 µM) in various stem/progenitor cells. | 2942.34元/10 MG; | 咨询 | ||||||||||||||||||||||||||||||||
产品说明 一般描述 A cell-permeable isoxazole compound that selectively induces robust neuronal differentiation (Effective concentration = 20 µM) in various stem/progenitor cells. Induces insulin expression, and activates ERK signaling and histone acetylation in MIN6 pancreatic β cells. The underlying excitation-neurogenesis signaling is comprised of, at least in part, an initial NMDA receptor- and L-type chanenels-mediated Ca2+ influx, followed by an activation of CaMKII, phosphorylation/nuclear export of the MEF2 repressor HDAC5, the subsequent de-repression of MEF2, and the eventual activation of the HDAC-MEF2 epigenetic/transcriptional regulatory network. 包装 10 mg in Plastic ampoule 警告 Toxicity: Standard Handling (A) 重悬 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 其他说明 Dioum, E.M., et al. 2011. Proc. Natl. Acad. Sci. USA108, 20713. 法律信息 CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany 基本信息
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