| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 |
| D796908 | MACKLIN | 去氧胆酸 | 10mM in DMSO | 125元/1ml; | 展开 |
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| D806701 | MACKLIN | 去氧胆酸 | 98% | 54元/5g; 203元/25g; 666元/100g; 2712元/500g; | 展开 |
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| C0315 | TCI | Deoxycholic Acid | >98.0%(T)(HPLC) | 285元/25G; 890元/100G; | 展开 |
基本信息 | 纯度/分析方法 | >98.0%(T)(HPLC) | | 分子式/分子量 | C24H40O4 = 392.58 | | 外观与形状(20℃) | 固体 | | Reaxys-RN | 3219882 | | SDBS (AIST Spectral DB) | 7675 | | Merck Index (14) | 2899 | | MDL编号 | MFCD00003673 |
技术规格 | Appearance | White powder to crystal | | Purity(HPLC)(CAD) | min. 98.0 area% | | Purity(Neutralization titration) | min. 98.0 % | | Melting point | 173.0 to 178.0 ℃ | | Specific rotation [a]20/D | +54.0 to +58.0 deg(C=1, EtOH) | | Solubility in Methanol | almost transparency |
物性(参考值) | 熔点 | 176 ℃ | | 比旋光度 [α]D | 56° (C=1,EtOH) |
安全信息 | 图形或危害标志 |  | | 信号词 | 警告 | | 危险性说明 | H302 : 吞咽有害。
H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
| | 防范说明 | P501 : 将内装物/容器送到批准的废物处理厂处理。
P270 : 使用本产品时不要进食、饮水或吸烟。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染：用水充分清洗。
P337 + P313 : 如仍觉眼刺激：求医/就诊。
P305 + P351 + P338 : 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服，清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激：求医/就诊。
P301 + P312 + P330 : 如误吞咽：如感觉不适，呼叫急救中心/医生。漱口。
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相关法规 |
| 393388 | J&K | Deoxycholic Acid | 98% | 221元/25G; 750元/100G; 2969元/500G; | 展开 |
基本信息 | 分子式 | C24H40O4 | | 分子量 | 392.58 | | 熔点 | 171-174 | | MDL编码 | MFCD00003673 | | Beilstein | 3219882 | | Merck | 14,2899 | | EINECS 编号 | 201-478-5 |
安全信息 | 图形或危害标志 | | | 提示语 | Warning | | 危险说明 | H302
H315
H319
H335 | | 防范说明 | P261
P305+P351+P338 | | WGK | 3 | | RTECS | FZ2100000 |
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| B20061 | Alfa Aesar | Deoxycholic Acid | 99% | 422元/25g; 1263元/100g; | 展开 |
应用
Deoxycholic acid has been used in a modified procedure to recover 40-80% of a protein from a 1 µg/mL solution. It forms complexes with fatty acid. Used as an emulsifying agent in food, a precursor in the synthesis of cortisone, and a gallbladder stimulant. It has been used to study assess how physiological concentrations of ursodeoxycholic acid (UDCA) vs. deoxycholic acid (DCA) affect barrier function in mouse intestinal tissue. Deoxycholic acid has been used in a study to assess a pH-Responsive Mechanism of a Deoxycholic Acid and Folate Co-Modified Chitosan Micelle under Cancerous Environment. It has also been used in a study to investigate dose-dependent anti-inflammatory effect of ursodeoxycholic acid in experimental colitis. 备注
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. 基本信息 MDL
MFCD00003673 EINECS
201-478-5 分子式
C24H40O4 分子量
392.58 熔点
172-176° 灵敏度
Ambient temperatures. 形态
Powder 溶解性
The free acid is soluble at 0.044 g/L in water at 20°C. Solubility in methanol is almost transparent. Beilstein
3219882 Merck
14,2899 GHS危害和防范说明 GHS符号
Hazard Statements
H302-H315-H319-H335
Harmful if swallowed.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation. Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations. 安全信息 危险类别
22-36/37/38
Harmful if swallowed.Irritating to eyes, respiratory system and skin. 安全等级
26-36/37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves.This material and its container must be disposed of as hazardous waste 欧盟危险品标志
 RTECS
FZ2100000 TSCA
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| C14814 | Alfa Aesar | Deoxycholic Acid | 98.5% | 716元/25g; 1824元/100g; 10082元/500g; | 展开 |
基本信息 Ref#
14814 MDL
3673 分子式
C24 H40 O4 分子量
392.57 |
| 1171273 | USP | Deoxycholic Acid (Desoxycholic Acid) | United States Pharmacopeia (USP) Reference Standard | 7418.77元/100 MG; | 展开 |
产品说明 一般描述 This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia. 分析说明 These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. 其他说明 USP issued SDS can be found here.
Sales restrictions may apply. 基本信息 | 经验(实验)分子式 | C24H40O4 | | 分子量 | 392.57 | | Beilstein | 3219882 | | MDL编号 | MFCD00003673 | | NACRES | NA.24 |
产品性质 | 等级 | pharmaceutical primary standard | | manufacturer/tradename | USP | | mp | 171-174 ℃ (lit.) | | 格式 | neat | | SMILES string | C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C | | InChI | 1S/C24H40O4/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3/h14-21,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-/m1/s1 | | InChI key | KXGVEGMKQFWNSR-LLQZFEROSA-N |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H302 | | 预防措施声明 | P301 + P312 + P330 | | 危险分类 | Acute Tox. 4 Oral | | 储存分类代码 | 13 - Non Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| D2510 | Sigma-Aldrich | Deoxycholic Acid | ≥98% (HPLC) | 231.23元/10 G; 1523.4元/100 G; 6147.22元/500 G; | 展开 |
产品说明 一般描述 脱氧胆酸是一种促炎剂。 应用 脱氧胆酸已被用于评估在癌性环境下，脱氧胆酸和叶酸共改性壳聚糖胶束的 pH 响应机制。 它还被用于研究熊去氧胆酸在实验性结肠炎中的剂量依赖性抗炎作用。 包装 10, 100, 500 g in poly bottle 生化/生理作用 胆汁酸 其他说明 Scripps Center for Metabolomics(斯克里普斯代谢组学中心)独立生成的串联质谱数据，可以PDF格式查看或下载。 D2510.pdf 经过测试的代谢物在 Scripps Center for Metabolomics(斯克里普斯代谢组学中心) METLIN 代谢物数据库中有重点介绍。更多信息请见sigma.com/metlin。 基本信息 | 经验(实验)分子式 | C24H40O4 | | 分子量 | 392.57 | | Beilstein | 3219882 | | EC 号 | 201-478-5 | | MDL编号 | MFCD00003673 | | PubChem化学物质编号 | 24893692 |
产品性质 | 生物来源 | bovine bile (ex gall bladder) | | 质量水平 | 200 | | 描述 | anionic | | 测定 | ≥98% (HPLC) | | 形式 | powder | | 分子量 | 392.57 g/mol | | mp | 171-174 ℃ (lit.) | | 官能团 | carboxylic acid | | 运输 | ambient | | 储存温度 | room temp | | SMILES string | C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C | | InChI | 1S/C24H40O4/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3/h14-21,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-/m1/s1 | | InChI key | KXGVEGMKQFWNSR-LLQZFEROSA-N | | Gene Information | human ... ATIC(471) |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H302 | | 预防措施声明 | P301 + P312 + P330 | | 危险分类 | Acute Tox. 4 Oral | | 储存分类代码 | 13 - Non Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable | | 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
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| 30960 | Sigma-Aldrich | Deoxycholic Acid | ≥99.0% (T) | 651.4元/25 G; 1568.12元/100 G; | 展开 |
产品说明 一般描述 Deoxycholic acid is an amphiphilic molecule and an important constituent of bile acid. It contains hydroxyl groups substituted at the 3α and 12α positions and a carboxyl group towards the end of the branched-chain. These moieties contribute to the hydrophilic nature of the molecule and the hydrophobic cyclopentanophenanthrene forms its center. 应用 Deoxycholic acid has been used as:
- a hyphal-inhibitory compound in an ex vivo assay to study the hyphal morphogenesis of Candida albicans in the gastrointestinal tract
- an internal standard to estimate the toxin concentration in the cell pellet
- a bile acid (BA) standard to quantitatively measure BA in various samples from treated mice by ultra-performance liquid chromatography triple quadrupole mass spectrometry
生化/生理作用 Deoxycholic acid, due to its amphiphilicity, significantly helps to solubilize, emulsify, and absorb fat, vitamins, and cholesterol in the body. High levels of intestinal deoxycholic acid might cause colorectal cancer by inducing oxidative stress and leading to DNA damage. It acts as an oncogene and pro-tumor factor. 其他说明 用于β-肾上腺素能受体的增溶 基本信息 | 经验(实验)分子式 | C24H40O4 | | 分子量 | 392.57 | | Beilstein | 3219882 | | EC 号 | 201-478-5 | | MDL编号 | MFCD00003673 | | PubChem化学物质编号 | 329753610 | | NACRES | NA.77 |
产品性质 | 质量水平 | 100 | | 生物来源 | ox bile | | 描述 | anionic | | 测定 | ≥99.0% (T) | | 形式 | powder | | 旋光性 | [α]20/D +54±1°, c = 1% in ethanol | | 分子量 | 392.57 g/mol | | 杂质 | ≤1% cholic acid (TLC) | | mp | 170-175 ℃
171-174 ℃ (lit.) | | 官能团 | carboxylic acid | | SMILES string | C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C | | InChI | 1S/C24H40O4/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3/h14-21,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-/m1/s1 | | InChI key | KXGVEGMKQFWNSR-LLQZFEROSA-N | | Gene Information | human ... ATIC(471) |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H302 | | 预防措施声明 | P301 + P312 + P330 | | 危险分类 | Acute Tox. 4 Oral | | 储存分类代码 | 13 - Non Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable | | 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
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| 358046 | Fluorochem | (4R)-4-[(1S,2S,5R,7R,10R,11S,14R,15R,16S)-5,16-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]pentanoic acid | = 99.5% (Titration) | 594元/25g; 1452元/100g; 3476元/250g; 11242元/1kg; | 展开 |
基本信息 | CAS Number | 83-44-3 | | MDL Number | MFCD00003673 | | Melting Point | 172-176℃ |
安全信息 | 图形或危害标志 | | | 危险性说明 | H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
| | 防范说明 | P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: .
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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