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CAS: 821-48-7
分子式: C4H10Cl3N
分子量: 178.49
熔点: 210-215℃
中文名称: 
双(2-氯乙基)胺盐酸盐
二(β-氯乙基)胺盐酸盐
英文名称: 
2,2'-dichloro-diethylamin hydrochloride
2,2'-dichlorodiethylamine hydrochloride
2-chloro-n-(2-chloroethyl)ethanamine hydrochloride
beta,beta'-dichlorodiethylamine hydrochloride
bis(2-chloroethyl)amine hydrochloride
bis(2-chloroethyl)ammonium chloride
bis(beta-chloroethyl)-amine hydrochloride
di-2-chloroethylamine hydrochloride
2-chloro-n-(2-chloroethyl)-ethanamin hydrochloride
leo 72a
n,n-bis(2-chloroethyl)amine hydrochloride
nc 26
nor-hn2 hydrochloride
nor-lost hydrochlorid
nornitrogen mustard hydrochloride
nsc 10873
sk 555
tl 161
Ethanamine,2-chloro-N-(2-chloroethyl)-,hydrochloride
展开更多英文名
性质描述: 熔点212-214℃。
生产方法: 由二乙醇胺和氯化亚砜反应得到。将氯化亚砜溶于氯仿中,于0℃以下滴加二乙醇胺和氯仿的混合液。控制滴加速度,使温度维持在-4-6℃,加完后,保温搅拌30min。再在室温搅拌1h,加热至60-65℃,待结晶全部析出后,加无水乙醇,加热回流使全部溶解。趁热倒出,自然冷却,析出结晶。次日过滤,用氯仿或无水乙醇洗涤2次。干燥,得成品,收率76%。
用途: 医药中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
B802672MACKLIN双(2-氯乙基)胺盐酸盐98%30元/25g;   49元/100g;   199元/500g;   850元/2.5kg;   展开
储存:室温
状态:白色到灰白色粉末
B1210TCIBis(2-chloroethyl)amine Hydrochloride>99.0%(T)265元/25G;   475元/100G;   1490元/500G;   展开

基本信息

纯度/分析方法>99.0%(T)
分子式/分子量C4H9Cl2N・HCl = 178.48
外观与形状(20℃)固体
Reaxys-RN3550356
PubChem物质ID87564146
MDL编号MFCD00012515

技术规格

AppearanceWhite to Light yellow to Light orange powder to crystaline
Purity(Argentometric Titration)min. 99.0 %
Purity(Nonaqueous Titration)min. 99.0 %

物性(参考值)

熔点213 ℃

安全信息

图形或危害标志
信号词警告
危险性说明H302 : 吞咽有害。
H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
H341 : 怀疑可造成遗传性缺陷。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P270 : 使用本产品时不要进食、饮水或吸烟。
P202 : 在阅读并明了所有安全措施前切勿搬动。
P201 : 使用前取得专用说明。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P308 + P313 : 如接触到或有疑虑:求医/就诊。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
P301 + P312 + P330 : 如误吞咽:如感觉不适,呼叫急救中心/医生。漱口。
P405 : 存放处须加锁。

相关法规

RTECS#IA1225000
260048J&KBis(2-chloroethyl)amine Hydrochloride98%81元/25G;   202元/100G;   877元/500G;   展开

基本信息

分子式C4H9Cl2N·HCl
分子量178.49
熔点212-214
MDL编码MFCD00012515
Beilstein3550356
EINECS 编号212-479-5

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
防范说明P261
P305+P351+P338
WGK3
RTECSIA1225000
TSCA
A13118Alfa AesarBis(2-chloroethyl)amine Hydrochloride98%465元/50g;   1470元/250g;   5377元/1000g;   展开

应用
Bis(2-chloroethyl)amine hydrochloride is used as an intermediate in chemicals synthesis and building block for piperazine derivatives.

备注
Stable under recommended storage conditions. Incompatible with oxidizing agents and bases.

基本信息

MDL
MFCD00012515

EINECS
212-479-5

分子式
C4H9Cl2N?HCl

分子量
178.49

熔点
211-215°

灵敏度
Ambient temperatures.

形态
Crystalline powder

溶解性
Partly miscible in water.

Beilstein
3550356

GHS危害和防范说明

GHS符号

Hazard Statements
H302-H331-H314-H318-H340-H350
Harmful if swallowed.Toxic if inhaled.Causes severe skin burns and eye damage.Causes serious eye damage.May cause genetic defects.May cause cancer.

Precautionary Statements
P260h-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
8

包装组
II

危险类别
45-46-22-23-34
May cause cancer.May cause heritable genetic damage.Harmful if swallowed.Toxic by inhalation.Causes burns.

安全等级
53-4-9-20-26-36/37/39-45-60
Avoid exposure - obtain special instructions before use.Keep away from living quarters.Keep container in a well-ventilated place.When using do not eat or drink.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).This material and its container must be disposed of as hazardous waste

RTECS
IA1225000

TSCA

C10632Alfa AesarBis(2-chloroethyl)amine Hydrochloride98%1343元/100g;   展开

基本信息

Ref#
10632

MDL
12515

分子式
C4 H9 Cl2 N . H Cl

分子量
178.49

安全信息

危险等级
8

包装组
II

8.20159Sigma-AldrichBis(2-chloroethyl)ammonium chloridefor synthesis343.5元/100 G;   展开

产品说明

分析说明

Assay (argentometric): ≥ 98.0 %
Melting range (lower value): ≥ 210 °C
Melting range (upper value): ≤ 215 °C
Identity (IR): passes test

基本信息

线性分子式(ClCH2CH2)2NH2Cl
分子量178.49
MDL编号MFCD00012515
EC索引号212-479-5

产品性质

质量水平200
效能1150 mg/kg LD50, oral (Rat)
mp212-215 ℃ (decomposition)
溶解性 >100 g/L
储存温度2-30℃
InChI1S/C4H9Cl2N.ClH/c5-1-3-7-4-2-6;/h7H,1-4H2;1H
InChI keyYMDZDFSUDFLGMX-UHFFFAOYSA-N

安全信息

象形图GHS05GHS07
警示用语:Danger
危险声明H290 - H302 - H314
预防措施声明P234 - P260 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B
储存分类代码8A - Combustible, corrosive hazardous materials
WGKWGK 3
闪点(F)No information available.
闪点(C)No information available.
B38503Sigma-AldrichBis(2-chloroethyl)amine Hydrochloride98%325.36元/25 G;   675.21元/100 G;   1132.03元/250 G;   展开

基本信息

线性分子式(ClCH2CH2)2NH·HCl
分子量178.49
Beilstein3550356
EC 号212-479-5
MDL编号MFCD00012515
PubChem化学物质编号24891737
NACRESNA.22

产品性质

质量水平200
测定98%
mp212-214 ℃ (lit.)
SMILES stringCl.ClCCNCCCl
InChI1S/C4H9Cl2N.ClH/c5-1-3-7-4-2-6;/h7H,1-4H2;1H
InChI keyYMDZDFSUDFLGMX-UHFFFAOYSA-N

安全信息

象形图GHS05GHS07
警示用语:Danger
危险声明H290 - H302 - H314
预防措施声明P234 - P260 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B
储存分类代码8A - Combustible, corrosive hazardous materials
WGKWGK 3
闪点(F)No information available.
闪点(C)No information available.
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
078560FluorochemBis(2-chloroethyl)amine Hydrochloride95%220元/1g;   242元/10g;   264元/25g;   924元/100g;   1936元/500g;   展开

基本信息

CAS Number821-48-7
MDL NumberMFCD00012515

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
H341: Suspected of causing genetic defects ..
防范说明 P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P281: Use personal protective equipment as required.
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: .
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308 + P313: IF exposed or concerned: Get medical advice/ attention.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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