CAS 80938-69-8; (+)-threo-1-phenyl-2-decanoylamino-3-*morpholino-

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货号

品牌

产品名称

规格

包装、参考价格

详情

D912715

MACKLIN

DL-threo-PDMP hydrochloride

98%

445元/5mg;

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储存：-20°C，密闭，干燥

P7340

Sigma-Aldrich

(±)-threo-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol hydrochloride

13680.6元/100 MG;

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产品说明

生化/生理作用

Glucosylceramide synthase inhibitor; blocks formation of glucosylceramide from ceramide.

基本信息

经验(实验)分子式	C₂₃H₃₈N₂O₃·HCl
分子量	427.02
MDL编号	MFCD00236490
PubChem化学物质编号	24278649
NACRES	NA.77

产品性质

生物来源	synthetic (organic)
质量水平	100
测定	≥98% (TLC)
形式	powder
溶解性	water: 50 mg/mL, clear, colorless
储存温度	−20℃
SMILES string	Cl.CCCCCCCCCC(=O)N[C@H](CN1CCOCC1)[C@H](O)c2ccccc2
InChI	1S/C23H38N2O3.ClH/c1-2-3-4-5-6-7-11-14-22(26)24-21(19-25-15-17-28-18-16-25)23(27)20-12-9-8-10-13-20;/h8-10,12-13,21,23,27H,2-7,11,14-19H2,1H3,(H,24,26);1H/t21-,23-;/m1./s1
InChI key	HVJHJOYQTSEKPK-BLDCTAJRSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)

513100

Sigma-Aldrich

DL-threo-PDMP, Hydrochloride-CAS 80938-69-8-Calbiochem

PDMP closely resembles the natural sphingolipid substrate of brain glucosyltransferase and acts as a potent and competitive inhibitor of this enzyme.

3543.57元/50 MG;

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产品说明

一般描述

PDMP closely resembles the natural sphingolipid substrate of brain glucosyltransferase and acts as a potent and competitive inhibitor of this enzyme. Blocks the outgrowth of neurites and inhibits glycolipid synthesis in cultured NIH/3T3 cells.
PDMP closely resembles the natural sphingolipid substrate of brain glucosyltransferase and is a potent and competitive inhibitor of this enzyme. Blocks the outgrowth of neurites and inhibits glycolipid synthesis in cultured 3T3 cells.

包装

50 mg in Plastic ampoule

生化/生理作用

Primary Target
glycolipid synthesis in cultured NIH/3T3 cells
Product does not compete with ATP.
Reversible: no
Cell permeable: no

警告

Toxicity: Irritant (B)

其他说明

Rani, C.S., et al. 1995. J. Biol. Chem. 270, 2859.
Rosenwald, A.G. 1992. Biochemistry31, 3581.
Inokuchi, J., and Radin, N.S. 1987. J. Lipid Res.28, 565.
Vunnam, R.R., and Radin, N.S. 1980. Chem. Phys. Lipids26, 265.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C₂₃H₃₈N₂O₃ · xHCl
分子量	390.56 (free base basis)
MDL编号	MFCD00236490

产品性质

质量水平	100
测定	≥98% (TLC)
形式	solid
manufacturer/tradename	Calbiochem^®
储存条件	OK to freeze
颜色	white
溶解性	DMSO: soluble ethanol: soluble methanol: soluble
运输	ambient
储存温度	−20℃

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable