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CAS: 80-70-6
分子式: C5H13N3
分子量: 115.18
沸点: 160-162℃
熔点: -30-54℃
中文名称: 
N,N,N',N'-四甲基胍
N,N,N,N-四甲基胍
1,1,3,3-四甲基胍
四甲基胍
英文名称: 
1,1,3,3-Tetramethyl guayyniaine
N,N'-Tetramethyl guanidine
1,1,3,3-tetramethyl-guanidine
N,N,N',N'-Tetramethyl-guanidine
Guanidine,N,N,N',N'-tetramethyl-
N,N,N',N'-tetramethyl-Guanidine
n,n,n',n'-tetramethyl-guanidin
1,1,3,3-tetramethylguanidine
N,N,N',N'-Tetramethylguanidine
TMG
tetramethylguanidine
展开更多英文名
性质描述: 该品为无色透明液体。
用途: 广泛应用于医药及化工原料合成。在医药中主要应用于头孢类抗生素生产中。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
T819032MACKLIN1,1,3,3-四甲基胍99%32元/25ml;   75元/100ml;   299元/500ml;   1288元/2.5L;   3745元/10L;   展开
储存:2~8°C
状态:无色至淡黄色至浅橙色至棕色澄清液体
折射率:n20/D 1.469
T0148TCI1,1,3,3-Tetramethylguanidine>99.0%(GC)(T)135元/25ML;   310元/100ML;   755元/500ML;   展开

基本信息

纯度/分析方法>99.0%(GC)(T)
分子式/分子量C5H13N3 = 115.18
外观与形状(20℃)液体
储存在惰性气体下存放于惰性气体之中
应避免的情况空气,湿气 (吸湿)
Reaxys-RN969608
PubChem物质ID87576150
SDBS (AIST Spectral DB)10085
MDL编号MFCD00008323

技术规格

AppearanceColorless to Light yellow to Light orange clear liquid
Purity(GC)min. 99.0 %
Purity(Nonaqueous Titration)min. 99.0 %

物性(参考值)

熔点-30 ℃
沸点163 ℃
闪点60 ℃
比重0.92
折射率1.47

安全信息

图形或危害标志
信号词危险
危险性说明H302 + H312 + H332 : 吞咽、皮肤接触或吸入有害。
H314 : 造成严重皮肤灼伤和眼损伤。
H226 : 易燃液体和蒸气。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P261 : 避免吸入粉尘/烟/气体/烟雾/蒸气/喷雾。
P270 : 使用本产品时不要进食、饮水或吸烟。
P240 : 容器和装载设备接地/等势联接。
P210 : 远离热源/火花/明火/热表面。禁止吸烟。
P233 : 保持容器密闭。
P243 : 采取防止静电放电的措施。
P241 : 使用防爆的电气/通风/照明设备。
P242 : 只能使用不产生火花的工具。
P271 : 只能在室外或通风良好之处使用。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
P370 + P378 : 火灾时:使用干砂、干粉或抗醇泡沫灭火。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P303 + P361 + P353 : 如皮肤(或头发)沾染:立即脱掉所有沾污的衣物。用水清洗皮肤/淋浴。
P301 + P330 + P331 : 如误吞咽:漱口。不要诱导呕吐。
P301 + P312 + P330 : 如误吞咽:如感觉不适,呼叫急救中心/医生。漱口。
P304 + P340 + P310 : 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。立即呼叫急救中心/医生。
P305 + P351 + P338 + P310 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。立即呼叫急救中心/医生。
P403 + P235 : 存放在通风良好的地方。保持低温。
P405 : 存放处须加锁。

运输信息

UN编号UN2920
类别8 / 3
包装类别 II
监管条件代码(*)
432690J&K1,1,3,3-Tetramethylguanidine99%60元/5G;   232元/100G;   665元/500G;   展开

基本信息

分子式C5H13N3
分子量115.18
熔点<-30
沸点52-54
闪点60
密度0.918
折光率(n20D)1.4670 - 1.4690
MDL编码MFCD00008323
Beilstein969608
EINECS 编号201-302-7

安全信息

图形或危害标志
提示语Danger
危险说明H226
H302
H314
防范说明P280
P305+P351+P338
P310
UN号码2920
危险分类8
次要危险性3
包装等级II
WGK1
TSCA
A12314Alfa Aesar1,1,3,3-Tetramethylguanidine99%236元/25ml;   500元/100ml;   1930元/500ml;   展开

应用
1,1,3,3-Tetramethylguanidine is employed as a polyurethane foam catalyst, as an accelerator for the syntheses of polysulfured rubber. It is also used as a strong base in the photochemical (couplers) and in the pharmaceutical (steroids) industries. It is essential for the preparation of alkyl nitriles from alkyl halides and 3'-alkylthymidines from 3'-nitrothymidines. It serves as an efficient and selective catalyst for the benzoylation of alcohols. It replaces the expensive bases 1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) and 1,5-Diazabicyclo[4.3.0]non-5-ene (DBN) in organic synthesis.

备注
Air sensitive. Incompatible with strong oxidizing agents, mineral and organic acids, carbon dioxide. Keep away from sources of ignition.

基本信息

MDL
MFCD00008323

EINECS
201-302-7

分子式
C5H13N3

分子量
115.18

熔点
<-30°

沸点
162°

闪点
60°(140°F)

密度
0.918

折射率
1.4690

灵敏度
Air Sensitive. Store under Argon. Ambient temperatures.

形态
Liquid

溶解性
Miscible with water.

Beilstein
969608

GHS危害和防范说明

GHS符号

Hazard Statements
H226-H302-H314-H318
Flammable liquid and vapour.Harmful if swallowed.Causes severe skin burns and eye damage.Causes serious eye damage.

Precautionary Statements
P210-P260h-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.Keep away from heat/sparks/open flames/hot surfaces. - No smoking.IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
8

包装组
II

危险类别
22-34
Harmful if swallowed.Causes burns.

安全等级
20-23-26-36/37/39-45-60
When using do not eat or drink.Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer).In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).This material and its container must be disposed of as hazardous waste

欧盟危险品标志

TSCA

C22129Alfa Aesar1,1,3,3-Tetramethylguanidine99%1537元/100g;   4409元/500g;   9518元/2kg;   展开

基本信息

Ref#
22129

MDL
8323

分子式
C5 H13 N3

分子量
115.18

闪点
50

密度
0.91

安全信息

危险等级
8

包装组
II

8.21897Sigma-AldrichN,N,N′,N′-Tetramethylguanidinefor synthesis310.95元/100 ML;   457.01元/250 ML;   展开

产品说明

分析说明

Assay (GC, area%): ≥ 98.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.915 - 0.917
Identity (IR): passes test

基本信息

线性分子式[(CH3)2N]2C=NH
分子量115.18
MDL编号MFCD00008323
EC索引号201-302-7

产品性质

质量水平200
蒸汽压2.9 hPa ( 20 ℃)
测定≥98.0% (GC)
自燃温度222 ℃
效能835 mg/kg LD50, oral (Rat)
expl. lim.1.0-7.5 % (v/v)
折射率n20/589 1.4659
pH值(酸碱度)12.7 (25 ℃, 10 g/L in H2O)
bp162 ℃/1013 hPa
mp<-80 ℃
转变温度flash point 50 ℃
密度0.92 g/cm3 at 20 ℃
储存温度2-30℃
InChI1S/C5H13N3/c1-7(2)5(6)8(3)4/h6H,1-4H3
InChI keyKYVBNYUBXIEUFW-UHFFFAOYSA-N

安全信息

象形图GHS02GHS05GHS07
警示用语:Danger
危险声明H226 - H290 - H302 - H314
预防措施声明P210 - P233 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Met. Corr. 1 - Skin Corr. 1B
储存分类代码3 - Flammable liquids
WGKWGK 1
闪点(F)122.0 °F - closed cup
闪点(C)50 ℃ - closed cup
011899FluorochemN,N-1,1,3,3-Tetramethylguanidine98+%286元/25g;   616元/100g;   2574元/500g;   展开

基本信息

CAS Number80-70-6
MDL NumberMFCD00008323
Boiling Point158.4℃
Melting Point-80℃
Density0.919

安全信息

图形或危害标志
危险性说明 H226: Flammable liquid and vapour.
H302: Harmful if swallowed.
H314: Causes severe skin burns and eye damage.
防范说明 P210: Keep away from – No smoking.
P233: Keep container tightly closed.
P240: Ground/bond container and receiving equipment.
P241: Use explosion-proof ./ equipment.
P242: Use only non-sparking tools.
P243: Take precautionary measures against static discharge.
P260: Do not breathe .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P301 + P330 + P331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303 + P361 + P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P310: Immediately call a POISON CENTER or doctor/physician.
P321: Specific treatment (see . on this label).
P330: Rinse mouth.
P363: Wash contaminated clothing before reuse.
P370 + P378: In case of fire: Use sand, CO2 or extinguishing powder for extinction.
P403 + P235: Store in a well-ventilated place. Keep cool.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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